Protein Alignment Hsp60A and CCT2

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 135/563 - (23%)
• Similarity: 233/563 - (41%)
• Gaps: 120/563 - (21%)

  Fly    39 GVDVLADAVAVTMGPKGRNVII---EQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANN 100
            |...:.|.|..|:||||.:.|:   .::.|..::|.||.|:.:::.:    .|..||::.|::..
  Fly    30 GAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGV----DNPAAKILVDMSRV 90

  Fly   101 TNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEE-- 163
            .:||.|||||:.||||..:.:|..:.:.:..:|..|..|...|.:...:.|...::..|:.:|
  Fly    91 QDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKF 155

  Fly   164 ------IAQVATISA----NGDQAIGNLISEAMKKVGRDG-----VITVKDGKTLTDELEVIEGM 213
                  ||: .|:|:    .......||..:|:.::...|     .|..|.|.||.|.. :.||.
  Fly   156 RNDLLNIAR-TTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSF-LDEGF 218

  Fly   214 KFDR--GYISPYFINSSK----GAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKPLVIIAE 272
            ..|:  |...|..|.:::    ...::.....:..|..|:.|:..|.. ||:|..::     :.|
  Fly   219 LLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIAD-LEMAEKEK-----MKE 277

  Fly   273 DIDG--EALSTLVVNR---------LKIGLQVAAVKAPGF-GDNRKSTLTDMAIASGGIVFG--D 323
            .:|.  :....:.:||         |....:|.:::...| |..|      :|..:||.:..  :
  Fly   278 KVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIER------LAYCTGGEIVSTFE 336

  Fly   324 DADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQE 388
            :..||||.:..|.:...:||      ||||                          .:...||.|
  Fly   337 NPSLVKLGECDVIEQVMIGE------DTLL--------------------------RFSGVKLGE 369

  Fly   389 RLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEG-IVPGGG-------TALLRCIE 445
                    ...:.:.|:::..::|....:||||....|.|:|. |:.|||       ||:|:...
  Fly   370 --------ACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAA 426

  Fly   446 KLEGVETTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAG------DYGYDALKG 504
            :..|.|.      :.:|...|||......||.|||.|.|.:|:  |.:||      ..|.|...|
  Fly   427 ETPGKEA------IAIEAFARALLSLPTAIADNAGYDSAQLVS--ELRAGHAQGKQTLGLDMELG 483

  Fly   505 EYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIPK 547
            :..::.|.||.:...|.|..:..||..|.::...:.::...|:
  Fly   484 KVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	134/558 (24%)
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	135/563 (24%)