Protein Alignment Hsp60A and Mkks

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001008354.1
• Gene: Mkks / 311456
• RGDID: 1308814
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 586
• Identity: 104/586 - (17%)
• Similarity: 193/586 - (32%)
• Gaps: 173/586 - (29%)

  Fly    40 VDVLADAVAVTMGPKGRNVIIEQSWGS-PKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNE 103
            :.||...:|...||.||...:....|. ...|.....:.:::.:......:   |...|.|:...
  Rat    26 LSVLKGIIASCYGPSGRLKQLHNGLGGCVCTTSQSSALLRNLSVTHPILKV---LTSSVQNHVCC 87

  Fly   104 EAGDGTTTATVLARAIAKEGFEKISKGANP---VEIRRGVM-LAVETVKDNLKTMSRPV---STP 161
            .:..|..||.:....|  |..::|  |..|   :::.:.:: |::..:|....:...||   ||.
  Rat    88 FSDCGLFTAILCCNLI--ENIQRI--GLTPTTAIKLNKYLLGLSISYLKSEACSCRIPVDFRSTH 148

  Fly   162 EEIAQVATISANGDQA---------IGNLI-----------SEAMKKVGRDGVITVKDGKTLTDE 206
            ..:..|.:|..:....         ||.||           :|....:|:..::.:| |:.:||.
  Rat   149 TFLNLVHSILTSKPACMLTRKEIDHIGALILKAFLLTIPESAEERMVLGKSIIVPLK-GQQVTDS 212

  Fly   207 LEVIEGMKFDRGYI-----------------------SPYFINSSKGA-----KVEFQDA----L 239
             .|:.|:..:...:                       |..|.|:.:|.     :|..::|    |
  Rat   213 -TVLPGLLIEASEVQLRRLLPTQKSSTLRVALFCASLSGDFSNAGEGTLVVHYQVSLENAVLEQL 276

  Fly   240 LLLSEKKISSVQSIIPALELANAQRKPLV----IIAEDIDG----EALSTLVVNRLKIGL----- 291
            |.|..:.:|....::...::.:...|..:    |||.|..|    |.||. |.....||.
  Rat   277 LNLGRQLVSDHVDLVLCQKVIHPSLKQFLSEHQIIAIDRVGVTLMEPLSK-VTGATPIGSLYPIV 340

  Fly   292 -----QVAAVKAPGFGDN-------RKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEV 344
                 .|..|::..||..       .::|:..:.:.|.    .|.|    .|::|::....:..:
  Rat   341 STTYGSVKDVRSARFGSKYFFHLLPNEATICSLLLCSR----NDTA----WEELKLTCQTAMHVL 397

  Fly   345 VITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVE 409
            .:|..:..:|.|.|              .:|...:.|.:.|:..      ...|::|..|.|:.|
  Rat   398 QLTIKEPWVLLGGG--------------CVETHLAAYIRHKVHN------EAEAIVRDDGCSQAE 442

  Fly   410 VNEKKDRVHDALNATRAAVEEGIVPGGGTALL-------------------------RCIEKLEG 449
            ::...:....||.:...::|.    .||..|:                         ||     |
  Rat   443 LHIATEAFCSALESAAVSLEH----DGGEILIDMKYGHFWSCPADSASVGNWPDTLSRC-----G 498

  Fly   450 VETTNEDQKLGVEIVRRALR----MPCMTIAKNAGV------------DGAMVVAKVENQAGDYG 498
            ....|..::|...::|....    ..|:..|.:..|            .|..|..:..|...|..
  Rat   499 CGLYNSQEELSWSVLRSTYHPFAPQTCLPQAASGSVSNLTVDSFTAKLSGLQVAVETANLILDLS 563

  Fly   499 Y 499
            |
  Rat   564 Y 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	104/586 (18%)
Mkks	NP_001008354.1	Cpn60_TCP1	29..569	CDD:395068	103/583 (18%)