Protein Alignment Hsp60A and mcp60

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_592894.1
• Gene: mcp60 / 2543131
• PomBaseID: SPAC12G12.04
• Length: 582
• Species: Schizosaccharomyces pombe
• Alignment Length: 572
• Identity: 325/572 - (56%)
• Similarity: 432/572 - (75%)
• Gaps: 9/572 - (1%)

  Fly     3 RLPVSLARSSISRQLA---MRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSW 64
            |||:.:|...|..:.|   :|.||||::||.:.||.:|.|||.||.||:||:|||||||:|:|.:
pombe    11 RLPLRIAGRRIPGRFAVPQVRTYAKDLKFGVDARASLLTGVDTLARAVSVTLGPKGRNVLIDQPF 75

  Fly    65 GSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISK 129
            |||||||||||||:|:.|||||:|:||:||||||:.|||.|||||||||||.|||..|....::.
pombe    76 GSPKITKDGVTVARSVSLKDKFENLGARLVQDVASKTNEVAGDGTTTATVLTRAIFSETVRNVAA 140

  Fly   130 GANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGV 194
            |.||:::|||:.|||:.|.:.|:...|.::|.|||:||||||||||..||.|:::||::||::||
pombe   141 GCNPMDLRRGIQLAVDNVVEFLQANKRDITTSEEISQVATISANGDTHIGELLAKAMERVGKEGV 205

  Fly   195 ITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALEL 259
            ||||:|:|::|||||.|||||||||||||||...|..||||::.|:||||||:|:||.|:|:|||
pombe   206 ITVKEGRTISDELEVTEGMKFDRGYISPYFITDVKSQKVEFENPLILLSEKKVSAVQDILPSLEL 270

  Fly   260 ANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDD 324
            |..||:||||||||:|||||:..::|:|:..|||.|:|||||||||::.|.|:|:.:...||.|:
pombe   271 AAQQRRPLVIIAEDVDGEALAACILNKLRGQLQVVAIKAPGFGDNRRNMLGDLAVLTDSAVFNDE 335

  Fly   325 ADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQIED-TTSEYEKEKLQE 388
            .| |.:|..:...||..|.|.:||:||:::||.|....|..|..||:..:.| ..:|||||||||
pombe   336 ID-VSIEKAQPHHLGSCGSVTVTKEDTIIMKGAGDHVKVNDRCEQIRGVMADPNLTEYEKEKLQE 399

  Fly   389 RLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVETT 453
            |||:|:.|:|:::|||||||||||||||:.|||||.:|||.||::||.||:.::...:|..:.|.
pombe   400 RLAKLSGGIAVIKVGGSSEVEVNEKKDRIVDALNAVKAAVSEGVLPGAGTSFVKASLRLGDIPTN 464

  Fly   454 NEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAG---DYGYDALKGEYGNLIEKGII 515
            |.||||||||||:|:..|..||.:|||::|.::|.|::...|   :.|||..|..:.:|.|.|::
pombe   465 NFDQKLGVEIVRKAITRPAQTILENAGLEGNLIVGKLKELYGKEFNIGYDIAKDRFVDLNEIGVL 529

  Fly   516 DPTKVVRTAITDASGVASLLTTAEAVVTEIPKEDGAPA-MPGMGGMGGMGGM 566
            ||.|||||.:.||||||||:.|.|..:.:.|:|..||| .|||||||||.||
pombe   530 DPLKVVRTGLVDASGVASLMGTTECAIVDAPEESKAPAGPPGMGGMGGMPGM 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	300/523 (57%)
mcp60	NP_592894.1	GroEL	35..558	CDD:239460	300/523 (57%)