Protein Alignment Hsp60A and Tcp1

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_036802.1
• Gene: Tcp1 / 24818
• RGDID: 3832
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 138/588 - (23%)
• Similarity: 240/588 - (40%)
• Gaps: 139/588 - (23%)

  Fly    29 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKL 93
            |..:|:..:.....:|:.|..::||.|.:.::....|...||.||.|:.|.:|:    ::..||:
  Rat    14 GEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV----EHPAAKV 74

  Fly    94 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVML----AVETVKDNLKTM 154
            :.::|:..::|.|||||:..::|..:.|...|.:.:..:|..:..|..|    ||..:.:||
  Rat    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENL--- 136

  Fly   155 SRPVSTPEEIAQVATISA------------NGDQAIGNLISEAMKKVGRDGVITVKDGKTLTD-- 205
               :...:|:.:...|:|            ||| ...|::.        |.|:.||    .||
  Rat   137 ---IINTDELGRDCLINAAKTSMSSKIIGINGD-FFANMVV--------DAVLAVK----YTDIR 185

  Fly   206 --------ELEVIEG---MKFDRGYISPYFIN---SSKG-------AKVEFQDALLLLSEKKISS 249
                    .:.:::.   .:.:...|:.|.:|   .|:|       ||:...|..|..::.|: .
  Rat   186 GQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKL-G 249

  Fly   250 VQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAA---------VKAPGFGDNR 305
            ||.:|...|..:..|:.    ..||..|.:..::.....:.|....         |:|......|
  Rat   250 VQVVITDPEKLDQIRQR----ESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRR 310

  Fly   306 --KSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITK--DDTLLLKGKGKKDDVLRR 366
              |..|..:|.|||..:....|:|...|..:.:.|||..|||..:  ||.|:|
  Rat   311 VLKRDLKRIAKASGASILSTLANLEGEETFEATMLGQAEEVVQERICDDELIL------------ 363

  Fly   367 ANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVE-E 430
                   |::|.            ||.::.: :||  |:::...:|.:..:||||...:..:| :
  Rat   364 -------IKNTK------------ARTSASI-ILR--GANDFMCDEMERSLHDALCVVKRVLESK 406

  Fly   431 GIVPGGGTALLRCIEKLEGVETT--NEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKV--- 490
            .:|||||.........||...|:  :.:|....|..|..|.:| .|:|.||..|...:|||:
  Rat   407 SVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIP-NTLAVNAAQDSTDLVAKLRAF 470

  Fly   491 --ENQAGD-------YGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIP 546
              |.|...       .|.|.:.|:..:..:.|:.:|| :|:        |.||....||.:|.:.
  Rat   471 HNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPT-IVK--------VKSLKFATEAAITILR 526

  Fly   547 KED 549
            .:|
  Rat   527 IDD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	136/581 (23%)
Tcp1	NP_036802.1	TCP1_alpha	9..535	CDD:239451	138/588 (23%)