Protein Alignment Hsp60A and Tcp1

DIOPT Version :9

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_038714.2
• Gene: Tcp1 / 21454
• MGIID: 98535
• Length: 556
• Species: Mus musculus
• Alignment Length: 588
• Identity: 140/588 - (23%)
• Similarity: 240/588 - (40%)
• Gaps: 139/588 - (23%)

  Fly    29 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKL 93
            |..||:..:.....:|:.|..:.||.|.:.::....|...||.||.|:.|.:|:    ::..||:
Mouse    14 GEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEV----EHPAAKV 74

  Fly    94 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVML----AVETVKDNLKTM 154
            :.::|:..::|.|||||:..::|..:.|...|.:.:..:|..:..|..|    ||..:.:||
Mouse    75 LCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENL--- 136

  Fly   155 SRPVSTPEEIAQVATISA------------NGDQAIGNLISEAMKKVGRDGVITVKDGKTLTD-- 205
               :...:|:.:...|:|            |||. ..|::.        |.|:.||    .||
Mouse   137 ---IINTDELGRDCLINAAKTSMSSKIIGINGDY-FANMVV--------DAVLAVK----YTDAR 185

  Fly   206 --------ELEVIEG---MKFDRGYISPYFIN---SSKG-------AKVEFQDALLLLSEKKISS 249
                    .:.:::.   .:.:...|:.|.:|   .|:|       ||:...|..|..::.|: .
Mouse   186 GQPRYPVNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKL-G 249

  Fly   250 VQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAA---------VKAPGFGDNR 305
            ||.:|...|..:..|:.    ..||..|.:..::.....:.|....         |:|......|
Mouse   250 VQVVITDPEKLDQIRQR----ESDITKERIQKILATGANVILTTGGIDDMYLKYFVEAGAMAVRR 310

  Fly   306 --KSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITK--DDTLLLKGKGKKDDVLRR 366
              |..|..:|.|||..:....|:|...|..:|:.|||..|||..:  ||.|:|
Mouse   311 VLKRDLKHVAKASGASILSTLANLEGEETFEVTMLGQAEEVVQERICDDELIL------------ 363

  Fly   367 ANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVE-E 430
                   |::|.            ||.::.: :||  |:::...:|.:..:||||...:..:| :
Mouse   364 -------IKNTK------------ARTSASI-ILR--GANDFMCDEMERSLHDALCVVKRVLELK 406

  Fly   431 GIVPGGGTALLRCIEKLEGVETT--NEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKV--- 490
            .:|||||.........||...|:  :.:|....|..|..|.:| .|:|.||..|...:|||:
Mouse   407 SVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIP-NTLAVNAAQDSTDLVAKLRAF 470

  Fly   491 --ENQAGD-------YGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIP 546
              |.|...       .|.|.:.|:..:..:.|:.:|| :|:        |.||....||.:|.:.
Mouse   471 HNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPT-IVK--------VKSLKFATEAAITILR 526

  Fly   547 KED 549
            .:|
Mouse   527 IDD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	139/586 (24%)
		GroEL	24..544	CDD:239460	138/581 (24%)
Tcp1	NP_038714.2	chap_CCT_alpha	5..540	CDD:274081	140/588 (24%)
		TCP1_alpha	9..535	CDD:239451	140/588 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900