Protein Alignment Hsp60A and cct-2

DIOPT Version :9

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_741031.1
• Gene: cct-2 / 174421
• WormBaseID: WBGene00000378
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 619
• Identity: 135/619 - (21%)
• Similarity: 244/619 - (39%)
• Gaps: 162/619 - (26%)

  Fly     4 LPVSLARSSISRQLAMRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVII----EQSW 64
            |||.:.:.:          |::.| |...|.....|...:.|.|..|:||||.:.|:    .:|.
 Worm     2 LPVQILKDN----------AQEER-GESARLSSFVGAIAIGDLVKSTLGPKGMDKILISGNPESA 55

  Fly    65 GSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISK 129
            |..|:|.||.|:.|||.:    .|..||::.|::...:.|.|||||:.||||..:.||..:.:::
 Worm    56 GGIKVTNDGATILKSIGV----DNPAAKVLVDMSMTQDHEVGDGTTSVTVLAAELLKEAEKLVNQ 116

  Fly   130 GANPVEI----RRGVMLAVETVK-------DNLKTMSRPVSTPEEIAQVATISANGDQAIGNLI- 182
            ..:|..|    ||.:.:|.|::|       ||::         :::.::|..:      :|:.|
 Worm   117 RIHPQTIISGYRRALGIAQESLKKSSIESGDNIR---------DDLLKIARTT------LGSKIL 166

  Fly   183 ---SEAMKKVGRDGVITVKDGKTLTDELEVI-------------EGMKFDR--GYISPYFINSSK 229
               .|...::..|.|:.:|....| |.:::|             ||...::  |...|..:..:|
 Worm   167 SQHKEHFAQLAVDAVLRLKGSGNL-DAIQIIKKLGGSMNESYLDEGFLLEKLPGMFQPRRVEKAK 230

  Fly   230 ----GAKVEFQDALLLLSEKKISSVQSI--IPALELANAQRKPLVIIAEDIDGEALSTLVVN--- 285
                ...::.....:..|..::..|..:  :.|.|....:.|...|:|.:.:......|:.|
 Worm   231 ILIANTPMDTDKVKVFGSRVRVDGVAKVAELEAAEKLKMKEKVDKILAHNCNVFINRQLIYNYPE 295

  Fly   286 RLKIGLQVAAVKAPGF-GDNRKSTLTDMAIASGGIV-----------FGDDADLVKLEDVKVSDL 338
            :|....:|.|::...| |..|      :|:..||.:           || ..||::
 Worm   296 QLFADAKVMAIEHADFEGIER------LALVLGGEIVSTFDSPQTAQFG-SCDLIE--------- 344

  Fly   339 GQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVG 403
                |::|.:|..|...|                                  .:|....:::..|
 Worm   345 ----EIMIGEDRLLRFSG----------------------------------VKLGEACSVVLRG 371

  Fly   404 GSSEVEVNEKKDRVHDALNATRAAVEEG-IVPGGG-------TALLRCIEKLEGVETTNEDQKLG 460
            .:.:: ::|.:..:||||......|:|. .|.|.|       :|:....:|:.|.|.      |.
 Worm   372 ATQQI-LDESERSLHDALCVLVTHVKESKTVAGAGASEILMSSAIAVEAQKVAGKEA------LA 429

  Fly   461 VEIVRRALRMPCMTIAKNAGVDGAMVVAKVE----NQAGDYGYDALKGEYGNLIEKGIIDPTKVV 521
            ||...|||......|..|||:|.|.:|.::.    |...:.|.|..|||..::.:.|:|:...|.
 Worm   430 VEAFGRALAQLPTIICDNAGLDSAELVTRLRAEHANGRHNMGIDIEKGEVADVTKLGVIESYNVK 494

  Fly   522 RTAITDASGVASLLTTAEAVVTEIPK---EDGAP 552
            ...::.|:.....:...:.::...|:   :|..|
 Worm   495 LCMVSSAAEATEQILRVDDIIKAAPRARAQDNRP 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	130/606 (21%)
		GroEL	24..544	CDD:239460	128/586 (22%)
cct-2	NP_741031.1	chap_CCT_beta	5..522	CDD:274082	130/608 (21%)
		TCP1_beta	6..520	CDD:239452	129/605 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810