Protein Alignment Hsp60A and cct-4

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_495750.1
• Gene: cct-4 / 174330
• WormBaseID: WBGene00000379
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 139/584 - (23%)
• Similarity: 245/584 - (41%)
• Gaps: 95/584 - (16%)

  Fly     5 PVSLARSSISRQLAM---RGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGS 66
            |...|.::.:||.|.   |.: ||......||...:.....:||||..::||:|.:.:|:...|.
 Worm     3 PAVPAAAATARQSASGRERNF-KDKDKPESVRNSNIVAAKAVADAVRTSLGPRGMDKMIQSGNGD 66

  Fly    67 PKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGA 131
            ..||.||.|:...:.:    .:..||::.:::...:.||||||||..|:|.|:.......:|||.
 Worm    67 VTITNDGATILNQMSV----IHPTAKMLVELSKAQDIEAGDGTTTVVVMAGALLDAAQNLLSKGI 127

  Fly   132 NPVEIRRGVMLAVETVKDNLKTMSRPVSTPEE--IAQVATISANG------DQAIGNLISEAMKK 188
            :|..|......|....:..|..||.||....:  :.::||.|.|.      ...:..:...|:||
 Worm   128 HPTTISESFQSAAAEAEKILDEMSSPVDLSNDALLNKMATTSLNSKVVSQHSWLLAPMAVNAVKK 192

  Fly   189 V---GRDGVITVKDGKTL------TDELEVIEGMKFDR---GYISPYFINSSKGAKVEFQDALLL 241
            :   ..|..:.:|..|.:      .:|.|:|||...|:   |..:|..|..:|...::||
 Worm   193 IINSENDSNVNLKMIKIIKKMGDTVEESELIEGALIDQKTMGRGAPTRIEKAKIGLIQFQ----- 252

  Fly   242 LSEKKISSVQSII----PALELA-NAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGF 301
            :|..|......:|    ..::.| ..:|:.|:.|.:.|.....:.|::
 Worm   253 ISPPKTDMENQVIITDYAQMDRALKEERQYLLEICKQIKAAGCNVLLI----------------- 300

  Fly   302 GDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRR 366
               :||.|.| |:....:.|.....::.::|::..|:.....:       |..:.....|.....
 Worm   301 ---QKSILRD-AVNELALHFLAKMKIMCIKDIEREDIEFYSRI-------LGCRPVASVDHFNAD 354

  Fly   367 ANQIKDQIEDTTSEYEKEKLQERLARLASGV--------ALLRVGGSSEVEVNEKKDRVHDALNA 423
            |....|.:|:..:..:.:.::      .:||        .|||  ||:::.:.|....:||||..
 Worm   355 ALGYADLVEEIPTGGDGKVIK------VTGVQNPGHAVSILLR--GSNKLVLEEADRSIHDALCV 411

  Fly   424 TRAAV-EEGIVPGGGTALLRCIEKLEGVETTNEDQKLGVEIVRR----ALRMPCMTIAKNAGVDG 483
            .|..| ::.::||||...:....||..:..|   |....:...|    ||.:...|:|:|||:..
 Worm   412 IRCLVKKKALLPGGGAPEMEIAVKLRNLAQT---QHGATQYCWRAFADALELIPYTLAENAGLSP 473

  Fly   484 AMVVAKVENQAGD----YGYDALKGEYGNLIEKGIIDPTKVVRTAITDASG-VASLLTTAEAVV 542
            ...|.::.|...:    ||.:..||...:::|:.::.|..|..:||..||. |.|:|...:.|:
 Worm   474 IHTVTELRNNHANGNSSYGVNVRKGYVTDMVEEDVVQPLLVTASAIKQASECVRSILKIDDIVM 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	133/562 (24%)
cct-4	NP_495750.1	chap_CCT_delta	23..539	CDD:274083	133/564 (24%)