Protein Alignment Hsp60A and cct-3

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_494218.2
• Gene: cct-3 / 173581
• WormBaseID: WBGene00018782
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 135/595 - (22%)
• Similarity: 236/595 - (39%)
• Gaps: 154/595 - (25%)

  Fly    29 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKL 93
            |.:|:...:.....:||.:..::||:....::....|...:|.||..:.:.|.:|    :..||.
 Worm    21 GHQVQIGNINACKTIADVIRTSLGPRAMLKMLMDPMGGIVMTNDGNAILREITVK----HPAAKS 81

  Fly    94 VQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETV---KDNLKTMS 155
            :.::|...:||.|||||:..:||..:.......:.:..:|..|.:....|:|.:   .:|..:.:
 Worm    82 MIEIARTQDEETGDGTTSVIILAGEVMAHAQTYLEQKTHPTLIIKAYRQALEDMIQWSENKFSKT 146

  Fly   156 RPVSTPEEIAQVA-------TISANGDQAIGNLISEAMK--KVGRDGV--ITVK--------DGK 201
            ..::...|||:|.       .||...|.|: |:..:|:|  :|.:.||  |.:|        .|.
 Worm   147 VDITDDAEIAKVVKSCLGTKMISKWMDLAV-NISIQAVKTIRVEKAGVREIDIKRYCRIEKIPGG 210

  Fly   202 TLTDELEVIEGM---------KFDRGYISPYFI------NSSKGAKVEFQDALLLLSEKKISSVQ 251
            .:.|. :|::|:         |..|...:|..:      ...||   |.|.:|.::.|:.||
 Worm   211 RIEDS-QVVKGIVVNKDILHAKMRRRIENPRIVLLDCNLEYKKG---ESQTSLEIMREEDIS--- 268

  Fly   252 SIIPALELANAQR-------KPLVIIAEDIDGEALSTLVVN-RLKIGLQVAAVKAPGFGDNRKST 308
            :|:...|.|..::       ||.::..|    :.:|.|..: .||.|  :..::.....||.:
 Worm   269 AILEQEEQAIRKQCDEIIKLKPDLVFTE----KGISDLAQHFLLKAG--ITCLRRLKKTDNNR-- 325

  Fly   309 LTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVITKDD-------------TLLLKGKGKK 360
               :|...|..|..|.:|   |.|..|....|:.|||...|:             |::|:|..|
 Worm   326 ---LARVCGARVVHDTSD---LRDEDVGTKAQLFEVVKIADEYYTYVTAETTTACTVVLRGPSK- 383

  Fly   361 DDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATR 425
             ||                                              :||.:..:.|:|:..|
 Worm   384 -DV----------------------------------------------INEVERNLQDSLHVVR 401

  Fly   426 -AAVEEGIVPGGGT---ALLRCIE----KLEGVET-TNEDQKLGVEIVRRALRMPC--MTIAKNA 479
             ..:...:|||||.   ||.|.||    |::||:. ..:...|.:|::.|.|...|  .||.|..
 Worm   402 NIMINPKLVPGGGALEMALSREIEQQGAKMDGVKKWPYKAIGLALEVIPRTLIQNCGGSTIRKMT 466

  Fly   480 GVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIIDP----TKVVRTAITDASGVASLLTTAEA 540
            .: .|:.....||..  :|.|...|:..::.:..|.||    .:|::|||.    .:.:|...:.
 Worm   467 EL-RAIHAQNAENWT--FGVDGTSGDLVDMNKLEIWDPLAVRIQVLKTAIE----TSVMLLRIDD 524

  Fly   541 VVTEIPKEDG 550
            :|:...|..|
 Worm   525 IVSGTKKAVG 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	133/587 (23%)
cct-3	NP_494218.2	TCP1_gamma	8..528	CDD:239453	133/587 (23%)