Protein Alignment Hsp60A and CCT2

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_318752.5
• Gene: CCT2 / 1279082
• VectorBaseID: AGAMI1_012123
• Length: 534
• Species: Anopheles gambiae
• Alignment Length: 573
• Identity: 140/573 - (24%)
• Similarity: 242/573 - (42%)
• Gaps: 120/573 - (20%)

  Fly    29 GPEVRAMMLQGVDVLADAVAVTMGPKGRNVII---EQSWGSPKITKDGVTVAKSIELKDKFQNIG 90
            |...|.....|...:.:.|..|:||||.:.|:   .::.|..::|.||.|:.:::.:    .|..
Mosquito    19 GEIARLSSFVGAIAIGELVKSTLGPKGMDKILVANGRNAGQIEVTNDGATILRAVGV----DNPA 79

  Fly    91 AKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVK------- 148
            ||::.|::...::|.|||||:.||.|..:.:|..:.:.:..:|..|..|...|.:..:
Mosquito    80 AKILVDMSRVQDDEVGDGTTSVTVFAAELIREAEKLVEQKLHPQTIIAGWRQAADVARTALQGAA 144

  Fly   149 -DNLKTMSRPVSTPEEIAQVA--TISANGDQAIGNLISEAMKKVGRDGVITVKDGKTLT------ 204
             ||.....|   ..|::..:|  |:|:.    |.:...|...|:..|.|:.:|...:|:
Mosquito   145 ADNSANQER---FREDLLNIARTTLSSK----ILSQHKEHFAKLAVDAVLRLKGSGSLSAIQRIK 202

  Fly   205 ------DELEVIEGMKFDR--GYISPYFINSSKGAKVEFQDALLLLSEKKI--SSVQ----SIIP 255
                  :|..:.||...|:  |...|   .|.|.|.:...:..:...:.|:  ||::    |.|.
Mosquito   203 KLGGCLEESFLDEGFLLDKKPGVHQP---KSVKNANILIANTPMDTDKIKVFGSSIKVDSMSKIA 264

  Fly   256 ALELANAQR---KPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASG 317
            .||:|..::   |...|:|.:|:      :.:||..|                 ....:...|..
Mosquito   265 ELEVAEKEKMKEKVDKILAHNIN------VFINRQLI-----------------YNYPEQLFADA 306

  Fly   318 GIVFGDDADLVKLEDVKVSDLGQVGEVVITKDDTLLLKGKGKKDDVLRRANQIKDQI---EDTTS 379
            |::..:.||...:|.:.   |...||:|.|.|:..|:| .||.|        :.:|:   |||..
Mosquito   307 GVMAIEHADFDGIERLA---LVTGGEIVSTFDNPDLVK-LGKCD--------LIEQVMIGEDTLL 359

  Fly   380 EYEKEKLQERLARLASGVAL-----LRVGGSSEVEVNEKKDRVHDALNATRAAVEEG-IVPGGG- 437
            .:             |||.|     :.:.|:::..::|.:..:||||....|.|:|. :|.|||
Mosquito   360 RF-------------SGVPLGEACTVVIRGATQQIIDEAERSLHDALCVLAATVKESRVVYGGGC 411

  Fly   438 --TALLRCIEKLEGVETTNEDQKLGVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAG----- 495
              |.:...:.|| ..||..: :.:.:|...|||......||.|||.|.|.:|:  |.:||
Mosquito   412 SETLMATAVFKL-AAETAGK-EAMAIESFGRALMQLPTIIADNAGYDSAQLVS--ELRAGHSQGK 472

  Fly   496 -DYGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVASLLTTAEAVVTEIPK 547
             ..|.|...|:.|.:.|.||.:...|.|..:..|:..|.::...:.::...|:
Mosquito   473 STMGLDMNNGKVGCMKELGITESFAVKRQVLMSAAEAAEMILRVDNILKSAPR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	139/568 (24%)
CCT2	XP_318752.5	None