Protein Alignment Hsp60A and CCT5

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_307669.4
• Gene: CCT5 / 1269082
• VectorBaseID: AGAMI1_003337
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 608
• Identity: 132/608 - (21%)
• Similarity: 239/608 - (39%)
• Gaps: 137/608 - (22%)

  Fly     1 MFRLPVSLARSSISRQ-LAMRGYAKDVRF-GPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQS 63
            |..||.:.|.....|. :.:|......|. |.|.....:.....:|..:..::||||.:.::...
Mosquito     1 MMSLPGTFACDEYGRPFIVLRDQENQKRLTGNEAIKSHILAAKQIASIIRSSLGPKGLDKMMVSG 65

  Fly    64 WGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKIS 128
            .|...:|.||.|:.|   |.|....|| ||:..::.:.::|.|||||...|||.|:.::....:.
Mosquito    66 DGEVTVTNDGATIMK---LMDVDHEIG-KLMVQLSQSQDDEIGDGTTGVVVLAGALLEQAESLLD 126

  Fly   129 KGANPVEIRRGVMLAVETVKDNLKTMSRPV----STPEEIAQVATISANGDQAIGNLISEAMKKV 189
            :|.:|:.|..|..||.:....:|.|::.|.    ...|.:.:|| ::..|.:.: |.....|.::
Mosquito   127 RGIHPIRIADGFELAAQCAVKHLDTIAHPFPVSRDNKEPLIRVA-MTTLGSKIV-NKCHRQMAEI 189

  Fly   190 GRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALL---LLSEKKISSVQ 251
            ..|.|:||.|.:......|:|:             :....|.::|  |..|   ::.:|.:|..|
Mosquito   190 AVDAVLTVADLEKKDVNFELIK-------------LECKVGGRME--DTCLVKGVVVDKTMSHSQ 239

  Fly   252 --SIIPALELA-----------NAQRKPLVIIAEDID-----------------GEALSTLVV-- 284
              :::..::||           ..:.|..|..|:|..                 .:|.:||.:
Mosquito   240 MPTVLKDVKLAILTCPFEPPKPKTKHKLDVTSADDYRKLREYEQEKFLQMVKQVKDAGATLAICQ 304

  Fly   285 -------NRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVG 342
                   |.|.:..|:.||:..|..:     :..:|||:||.:      :.:.|::....||..|
Mosquito   305 WGFDDEANHLLLQQQLPAVRWVGGPE-----IELIAIATGGRI------VPRFEELSPDKLGTAG 358

  Fly   343 EV-----VITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRV 402
            .|     ..|||..|:                    |||..:              ...|.:|..
Mosquito   359 VVRELSFGTTKDKMLV--------------------IEDCLN--------------TRAVTVLIR 389

  Fly   403 GGSSEVEVNEKKDRVHDALNATRAAVEEG-IVPGGGTALLRCIEKLEGVETTNEDQKLGV--EIV 464
            ||:..|.. |.|..:||||...|:.:.:. ||.|||.|.:.|     .:....|..:|..  :..
Mosquito   390 GGNQMVTA-EAKRSIHDALCVVRSLIRDSRIVYGGGAAEISC-----SLAVAREADQLSTLEQYA 448

  Fly   465 RRALRMPC----MTIAKNAGVDGAMVVAKVENQAG-----DYGYDALKGEYGNLIEKGIIDPTKV 520
            .||..:..    :.:|:|:|:.....:::::.:.|     .:|.|.:.....::.|..:|:....
Mosquito   449 FRAFSVALESIPLALAENSGLSPIETLSELKARQGTENSSTFGVDCMLTGNSDMKEHHVIESLHS 513

  Fly   521 VRTAITDASGVASLLTTAEAVVT 543
            .:..|..|:.:..::...:.|.|
Mosquito   514 KKQQIVLATQLVKMILKIDDVRT 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	126/584 (22%)
CCT5	XP_307669.4	None