Protein Alignment Hsp60A and Cct5

DIOPT Version :10

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 553
• Identity: 128/553 - (23%)
• Similarity: 216/553 - (39%)
• Gaps: 142/553 - (25%)

  Fly    33 RAMMLQGVDVL------ADAVAVTM----GPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQ 87
            |...|.|::.|      |.|||.||    ||.|.:.::....|...||.||.|:...:::..:.
Mouse    24 RKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTITNDGATILSMMDVDHQI- 87

  Fly    88 NIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLK 152
               |||:.:::.:.::|.|||||...|||.|:.:|..:.:.:|.:|:.|..|...|......:|.
Mouse    88 ---AKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARIAIQHLD 149

  Fly   153 TMSRPV----STPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVITVKD-------------- 199
            .:|..|    :.||.:.|.|..:. |.:.| |.....|.::..:.|:||.|
Mouse   150 KISDKVLVDINNPEPLIQTAKTTL-GSKVI-NSCHRQMAEIAVNAVLTVADMERRDVDFELIKVE 212

  Fly   200 GKT--LTDELEVIEGMKFDRGYISPYFINSSKGAK-----------------------VEFQDAL 239
            ||.  ..::.::|:|:..|:.:..|........||                       ||...||
Mouse   213 GKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTKHKLDVMSVEDYKAL 277

  Fly   240 LLLSEKKISSVQSIIPALELANAQRKPLVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDN 304
            ....::|.   :.:|..::...|.   |.|.....|.||...|:.|.|      .||:..|..:
Mouse   278 QKYEKEKF---EEMIKQIKETGAN---LAICQWGFDDEANHLLLQNGL------PAVRWVGGPE- 329

  Fly   305 RKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGEVVI--TKDDTLLLKGKGKKDDVLRRA 367
                :..:|||:||.:....::|.   ..|:...|.|.|:..  |||..|::
Mouse   330 ----IELIAIATGGRIVPRFSELT---SEKLGFAGVVQEISFGTTKDKMLVI------------- 374

  Fly   368 NQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEG- 431
                            ||.:.      |....:.:.|.:::.:.|.|..:||||...|..:.:.
Mouse   375 ----------------EKCKN------SRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNR 417

  Fly   432 IVPGGGTALLRCIEKLEGVETTNEDQK------LGVEIVRRALRMPCMTIAKNAGVDGAMVVAKV 490
            :|.|||.|.:.|     .:..:.|..|      ..:.....||.:..|.:::|:|::....:.:|
Mouse   418 VVYGGGAAEISC-----ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEV 477

  Fly   491 -------ENQAGDYGYDAL-KG----EYGNLIE 511
                   .|.|  .|.|.| ||    :|.::||
Mouse   478 RARQVKESNPA--LGIDCLHKGSNDMQYQHVIE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	GroEL	24..544	CDD:239460	128/553 (23%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	128/553 (23%)