Protein Alignment Hsp60A and CCT7

DIOPT Version :9

• Sequence 1: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_006420.1
• Gene: CCT7 / 10574
• HGNCID: 1622
• Length: 543
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 134/550 - (24%)
• Similarity: 230/550 - (41%)
• Gaps: 60/550 - (10%)

  Fly    37 LQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKDGVTVAKSIELKDKFQNIGAKLVQDVANNT 101
            :....|:|:||..|:||:|.:.:|....|...|:.||.|:.|.:::    .:..||.:.|:|.:.
Human    26 ISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDV----VHPAAKTLVDIAKSQ 86

  Fly   102 NEEAGDGTTTATVLARAIAKEGFEKISKGANPVEIRRGVMLAVETVKDNLKTMSRPVSTPEEIAQ 166
            :.|.|||||:.|:||....|:....:.:|.:|..|.|....|.:...:.:|.::..|...:::.|
Human    87 DAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAVTVKKADKVEQ 151

  Fly   167 VATISANGDQAIGN-LISEA---MKKVGRDGVITVKDGKTLTDELEVIEGMKFDRGYISPYFINS 227
            ...:......|:.: |||:.   ..|:..|.|:.:.|    ..:|::|...|...|.:....:.:
Human   152 RKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMMLDD----LLQLKMIGIKKVQGGALEDSQLVA 212

  Fly   228 SKGAKVEFQDALLLLSEKKISSVQSIIPALELA------NAQRKPLVIIAED----IDGEALSTL 282
            ....|..|..|...:..||..:.:..:..:||.      ||:.:  |...||    :|.|  ..:
Human   213 GVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIR--VHTVEDYQAIVDAE--WNI 273

  Fly   283 VVNRL-KI---GLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLEDVKVSDLGQVGE 343
            :.::| ||   |.:|...|.| .||.......|..:...|        .|..||:|.:.:. .|.
Human   274 LYDKLEKIHHSGAKVVLSKLP-IGDVATQYFADRDMFCAG--------RVPEEDLKRTMMA-CGG 328

  Fly   344 VVITKDDTLLLKGKGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLASGVALLRVGGSSEV 408
            .:.|..:.|       ..|||.|. |:   .|:|....|:........:..:...:||.|....:
Human   329 SIQTSVNAL-------SADVLGRC-QV---FEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFM 382

  Fly   409 EVNEKKDRVHDALNATRAAVE-EGIVPGGGTALLRCIEKLEGV-ETTNEDQKLGVEIVRRALRMP 471
            |..|:.  :|||:...|.|:: :.:|.|||...:...:.|... .|....|:|.:....:||.:.
Human   383 EETERS--LHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEII 445

  Fly   472 CMTIAKNAGVDGAMVVAKV---ENQAGD-YGYDALKGEYGNLIEKGIIDPTKVVRTAITDASGVA 532
            ...:..|||.|...::.|:   ..|.|. ||.|....:..:..|..:.:|..|...|:|.||..|
Human   446 PRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAA 510

  Fly   533 SLLTTAEAVVTEIPKEDGAPAMPGMG-GMG 561
            .|:.:.:..:........||...|.| |.|
Human   511 CLIVSVDETIKNPRSTVDAPTAAGRGRGRG 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	128/535 (24%)
		GroEL	24..544	CDD:239460	128/530 (24%)
CCT7	NP_006420.1	TCP1_eta	5..525	CDD:239456	128/533 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..543		5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810