Protein Alignment CG42249 and AgaP_AGAP005457

DIOPT Version :9

• Sequence 1: NP_001259438.1
• Gene: CG42249 / 32043
• FlyBaseID: FBgn0259101
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_315460.4
• Gene: AgaP_AGAP005457 / 1276150
• VectorBaseID: AGAP005457
• Length: 543
• Species: Anopheles gambiae
• Alignment Length: 557
• Identity: 225/557 - (40%)
• Similarity: 346/557 - (62%)
• Gaps: 27/557 - (4%)

  Fly     7 RLTWSLVVVVAVMAVMCSSAEAADKEG--FPVAIIHINDLHARFEATDTSGGTCDEGEECIGGYP 69
            :||.:|||.||::     |...|.::|  ||:.:||.|||:||:...:..|.||...|.|.||||
Mosquito     6 QLTVALVVAVALV-----SFAQAQQDGPLFPLTVIHFNDLYARYNQVNLEGFTCVGQERCQGGYP 65

  Fly    70 RTVYTVKRLLQEQAELNPIYINAGDSFQGTLWYNIGRWNVTQQLLNLLPADVMTLGNHEFDHGVE 134
            |.| :|.|.||.:|| |.:|:|:|.||:|||||.:.||.|...:||:||||.||||..:|.||:|
Mosquito    66 RQV-SVVRQLQAEAE-NSLYVNSGGSFKGTLWYTVHRWEVVAAMLNVLPADAMTLGRFDFFHGLE 128

  Fly   135 GVVPFLETVDTNMLVANMDCAHEPTMEGKYNKSMIIERSGRKIGVIGVILETTYDLANTGKVIFR 199
            |:.||:|..:|.:::.|:|.:.|.:.. .:.:|:::|||||:||::|||......:.|.|.:.|.
Mosquito   129 GLNPFMEASETPIVLTNVDNSAEQSFV-NFERSVVVERSGRRIGILGVIRPDVSAIGNPGNLTFS 192

  Fly   200 NESDTIREEAQLLKAQGANIIIVVSHCGYDVDQQIAANAGDWIDVIVGSHSHTFLYTGDPPG-PH 263
            :..:.:|||:..|.|.|.:|:||:|:.|::.::::|.|.|..:|:|||..|:|.|:.||... |.
Mosquito   193 DPVEAVREESARLAADGVDIVIVLSYYGHNSERRMARNCGPHVDLIVGGFSNTVLFNGDATDFPL 257

  Fly   264 TPSGDYPTEVIHSSGHRVLIVQASAYARYVGNLIVYFDDNGDVLDYEGDPLYMDQSVPEDDIVLQ 328
            ...|||||......|.|||:|||.:|.|.||||.::||::|::..:||:|:::|.:||||..|:.
Mosquito   258 EVEGDYPTVEFQPDGRRVLVVQAGSYGRLVGNLTLFFDEDGEIEQWEGNPVFLDANVPEDPAVMS 322

  Fly   329 AMVPWQLEMKPIAERTVGQSRVNLQQSQCSSGECNLGNFFTDAMLHAF--VKDASSSSEESWSNV 391
            |:.|::||::.:..|||..:.|::.:..|.:|||.||...||:|:.||  |.:|
Mosquito   323 ALEPFRLEVETLGNRTVAVAEVDMSRQDCVTGECLLGTLITDSMVRAFFPVYNA----------- 376

  Fly   392 TIALTSTGTFRVPIPAGNITYKQLFAMCPWQNRLVTLSLRGKHIVELLEHVVAPMNASSATPRSS 456
             |||.:.|..|..:.||.:||||||.:.|::|||.::.|||.||:.:||:.|:....|:.|.::.
Mosquito   377 -IALQNRGGIRGDLQAGTVTYKQLFEVLPFENRLYSMLLRGIHIMRVLEYSVSTATVSNGTVQAW 440

  Fly   457 RFLQVSGLRIRY--DLNADQRVFSVRVRCSKCLVPRYIPLDLEHKYRVVVMEYLANGKNGFSVIS 519
            ..|||||||..|  |....:|:.|:.|.|.:|....|.|::...:|||||.|:||.|.:.|:...
Mosquito   441 DLLQVSGLRATYRIDNPPGRRLVSLEVLCQQCSGEVYEPVNPFREYRVVVSEFLAEGGDLFATFP 505

  Fly   520 ENAEDPEFGPFDLDALMDYMNSTGPITTAIEQRIQFV 556
            .:..|.:.||.||:|..:|:....|:......||:|:
Mosquito   506 RDGMDLQQGPIDLEAFEEYVERRSPLRDEAGGRIRFI 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42249	NP_001259438.1	UshA	26..547	CDD:223808	214/527 (41%)
		MPP_CD73_N	36..316	CDD:277354	122/280 (44%)
		5_nucleotid_C	345..514	CDD:280945	67/172 (39%)
AgaP_AGAP005457	XP_315460.4	UshA	19..543	CDD:223808	218/539 (40%)
		MPP_CD73_N	32..310	CDD:277354	122/280 (44%)
		5_nucleotid_C	339..499	CDD:280945	67/171 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	289	1.000	Domainoid score	I3950
eggNOG	1	0.900	-	-		E1_COG0737
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52881
OrthoDB	1	1.010	-	-		D159192at33208
OrthoFinder	1	1.000	-	-		FOG0001036
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11575
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1114
TreeFam	1	0.960	-	-
	9	8.890