DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2061 and Lancl3

DIOPT Version :9

Sequence 1:	NP_001259437.1	Gene:	CG2061 / 32042	FlyBaseID:	FBgn0027498	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001178657.1	Gene:	Lancl3 / 302540	RGDID:	1563642	Length:	420	Species:	Rattus norvegicus

Alignment Length:	438	Identity:	170/438 - (38%)
Similarity:	246/438 - (56%)	Gaps:	44/438 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RRYLKNPFPDFAGGENTPFASDEEHIKNLICTYVDAILEHCHPNSDDEDNR----------GDLY 57
            :|...|.|.|:.|  :......||.:..|:.:.::.||:...|.....:.|          |.||
  Rat     4 KRCFANRFDDYQG--SLLAGQCEEAVAPLVTSTIERILQELPPLGGGAEARGATAAGSSCQGGLY 66

  Fly    58 VGNAGIAFMFWKLNSCEQTRDLYPALDHAASFIRNAK------VNANRYKKRSAE-RYSFLCGNA 115
            .|.||:|:|.:.::.    ..|:.|.  ...::|:||      ..|..:.:..|: |.:||.|.|
  Rat    67 SGVAGVAYMLYHVSQ----SPLFAAA--RERYLRSAKRLIDACSRAEEWGETDADTRAAFLLGGA 125

  Fly   116 GIYAVSAAISQALKETEELSDDLANFKSGIPCSKEFMHTKYGCDEVLVGRAGYLSGCYWLNDVLP 180
            |:|||:..:..||..::.: ..|:.|::...........:.|.||:.|||||||.....|...|.
  Rat   126 GVYAVATLVYHALGRSDYV-QPLSKFRALCAVCAPVSFLECGSDELFVGRAGYLCAALVLKQKLA 189

  Fly   181 EKKITDDDLVSICQLIVTSGREYSKQNNSPCPLMYQYHGTEYLGAAHGLCAILHMLLD-----SP 240
            ::.:|...:.:|||.|:.||::|:.:...|.||||.|:|||||||||||.:||.|||.     .|
  Rat   190 QEVLTPAQIKAICQAILDSGKQYALKKRKPFPLMYSYYGTEYLGAAHGLSSILQMLLSYHEHLKP 254

  Fly   241 WFRTLPISAPAAELRDIKRSIDFFLELQDSDGNFPVALEDLRSGRDKRLVHWCHGAPGAVYVLAK 305
            ..|.|           :.:|:||.:| |:.:.|:|..|.:... |:..||||||||||..|:.||
  Rat   255 SDREL-----------VWQSVDFLME-QEQNCNWPPELGETIE-RENELVHWCHGAPGIAYLFAK 306

  Fly   306 AYLIFKEEKYLASLRRCADMVWKKGFLRKGPGICHGVAGNGYVFLLLFRLTNEMRYLYRAHKFME 370
            ||||.|:.:||.:..||.::.|:||.|:|||||||||||:.||||||:|||...:|:|||.:|.:
  Rat   307 AYLISKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVFLLLYRLTGNSKYIYRAQRFAQ 371

  Fly   371 LLTNAEFKLRARTPDRPHSLYEGVAGTVCYLVDLLEPEQAYFPFMDVF 418
            .|...|||..:|..:..:|||||.:||||:|:|||:|.||.||...||
  Rat   372 FLFTEEFKAGSRVLESIYSLYEGFSGTVCFLIDLLQPNQAEFPLFSVF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2061	NP_001259437.1	euk_LANCL	56..413	CDD:271202	153/368 (42%)
Lancl3	NP_001178657.1	euk_LANCL	65..414	CDD:271202	153/368 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335024
Domainoid	1	1.000	275	1.000	Domainoid score	I1692
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13421
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2756
OMA	1	1.010	-	-		QHG49990
OrthoDB	1	1.010	-	-		D316897at33208
OrthoFinder	1	1.000	-	-		FOG0007580
OrthoInspector	1	1.000	-	-		oto97550
orthoMCL	1	0.900	-	-		OOG6_101476
Panther	1	1.100	-	-	LDO	PTHR12736
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X807
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910