Protein Alignment CG2076 and GHITM

DIOPT Version :10

• Sequence 1: NP_572681.1
• Gene: CG2076 / 32041
• FlyBaseID: FBgn0030263
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_055209.2
• Gene: GHITM / 27069
• HGNCID: 17281
• Length: 345
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 166/346 - (47%)
• Similarity: 221/346 - (63%)
• Gaps: 20/346 - (5%)

  Fly    13 AGAIKILAQSPAQLFR---ANANPNLN---------LSTVRTYARRVVRTREPVEEMR-APSLKE 64
            |..:..|...|:::|.   ..|:|.:.         |:..|.||   .:||..:...| ...|||
Human     3 AARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYA---TKTRIGIRRGRTGQELKE 64

  Fly    65 KLMGPPSANAY---SMGKGAAAGAAAVGLGALCYYGVGLGKQTSIADNAIMWPQFVRDRIQSTYA 126
            ..:.|.....:   .||:...||.||||||||||||:||..:....:.|::|||:|:|||.|||.
Human    65 AALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYM 129

  Fly   127 FFGGSCVLTAAAAAATFRSHRLLELASRGGILATIASLALVIGSGAVARSIEYQPGLGAKHLAWA 191
            :..||..|||.:|.|..|:..|:....||..:....:.|.::|:|.:.|||.|....|.|||||.
Human   130 YLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWL 194

  Fly   192 VHCAILGAVIAPICFMGGPILTRAALYTGGIVGGLSTIAACAPSDKFLYMGGPLAIGLGVVFASS 256
            :|..::|||:||:..:|||:|.|||.||.||||||||:|.||||:|||.||.||.:|||:||.||
Human   195 LHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSS 259

  Fly   257 LASMWLPPTTALGAGLASMSLYGGLVLFSGFLLYDTQRMVRRAEVYPQYSYTPYDPINASMSIYM 321
            |.||:|||||..||.|.|:::||||||||.|||||||::::||||.|.|....|||||:.:||||
Human   260 LGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYM 324

  Fly   322 DVLNIFIRIVTIL-SGGQRRK 341
            |.||||:|:.|:| :||.|:|
Human   325 DTLNIFMRVATMLATGGNRKK 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2076	NP_572681.1	GHITM	93..341	CDD:198413	137/248 (55%)
GHITM	NP_055209.2	GHITM	81..344	CDD:198413	146/262 (56%)