Protein Alignment sev and AT1G18160

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: NP_173254.2
• Gene: AT1G18160 / 838395
• AraportID: AT1G18160
• Length: 992
• Species: Arabidopsis thaliana
• Alignment Length: 1227
• Identity: 252/1227 - (20%)
• Similarity: 421/1227 - (34%)
• Gaps: 362/1227 - (29%)

  Fly  1338 ISCWVGSELHEELRLNQSALEAR-----VEHLQPDQTYHFQVEARVAATGAAAGAASHALHVAPE 1397
            :|.|:.|..|.:...:.:|..::     :||..|           |.:.....|..|.:....||
plant    58 LSNWLSSVTHRKSPSSSNATNSKEDDTTMEHGGP-----------VGSESGMQGLGSSSNSKDPE 111

  Fly  1398 VQAVPRVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAP 1462
            |:...::..|       |:|..|....    |:.:|.:     :|..|             ||.|
plant   112 VEEEYQIQLA-------LELSAREDPE----AAQIEAM-----KQFSL-------------GSRP 147

  Fly  1463 AKLARMRAEVLALAVDWIQRIVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLK 1527
            :......||::|..        ||              ..:...::.||:.|           ..
plant   148 SAPENTPAELMAYR--------YW--------------NYNCLGYDDKIVDG-----------FY 179

  Fly  1528 DLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGSELEWATVQPLIRLHAGSLEPGSETLNLVDN 1592
            ||..:....||      :..|....|:|..::||  :.|..|          |...|:..||:
plant   180 DLCGVMNESSL------KRIPPLVDLQGTLVSDG--VTWDAV----------LVNSSKDSNLL-- 224

  Fly  1593 QGKLCVYDVARQLCTASA-------LRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSIRAYGRRRQ 1650
            :.:....|:|.:..:||:       |..||.:|..|.:.|.:......|.|.  ||:
plant   225 RLEQMALDIAAKSKSASSSGFVNSELVRQLAVLVADYMGGPVLDPDSTLRAW--WSL-------- 279

  Fly  1651 QLEYTVELEPEEVRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLHLPMITASEDCPL 1715
                               :|........::||.  |||  .......|.|| ..::..|...|.
plant   280 -------------------SYSLKATLRSMVLPL--GSL--TIGLARHRALL-FKVLCDSVGVPC 320

  Fly  1716 PI-PGVRYQLNLTLAKEPGSEEHDHGMEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKK 1779
            .| .|.:|..:..:|.  .|.:.|.|.|.:.. |:|...:|...|        .:|:...|
plant   321 RIVKGQQYTGSDDVAM--NSIKTDDGREYIVD-LMGDPGTLIPAD--------AAGLQMDF---- 370

  Fly  1780 LALPTLVLAPLELLTASATPSPPRNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGEN 1844
                                    :.||...|||:::.|.:.......||              :
plant   371 ------------------------DDSVYSASPRDVDSSHVASSSSGVES--------------S 397

  Fly  1845 VQDRRE-WEAHERRLETAGTHRLTGIKPGSGYSL------WVQAHATPTKSNSSERLHVRSFAEL 1902
            :::..| |.| |.|..|.|: |......|.|..:      .|.:...|.:..||:..|..:.|..
plant   398 IEEHTESWSA-EHRSRTKGS-REENQSAGGGDLMIPNIREAVGSQKAPVQHLSSKPTHSFTHARS 460

  Fly  1903 PELQLLELGPYSLSLTWA-GTPDPLGSLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRYQCRL 1966
            |              :|. |...|.|             ||....:.::.:::..:...:...:|
plant   461 P--------------SWTEGVSSPAG-------------RRMKVKDVSQYMIDAAKENPQLAQKL 498

  Fly  1967 ---LLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAE---EVFRVTWTAARGNGAPIAL 2025
               ||.........|:   :|||     :.|.....:::.:||   |..:...|..:|....
plant   499 HDVLLESGVVAPRNLF---SEVY-----SESMEATGEIKSVAESNDEKGKDFGTIQQGRNQS--- 552

  Fly  2026 YNLEALQARSDIRRRRRRR-----RRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLH 2085
             ||..::....:.|.:.:.     |.:||..|..|.             :.||...        |
plant   553 -NLGPVRFLPPLPRPQSKAITHDLREHSGSGLGHLS-------------EHCNIDG--------H 595

  Fly  2086 SSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSPEKRGSLVLAIIAPAAIVSSCVLALVLVRKV 2150
            |.                   |..||      .|.:...::.:|:.|.|.:.||.|:|.......
plant   596 SD-------------------SSHSE------TSTDYPRNVPVAVAAAAVVASSMVVAAAKSANS 635

  Fly  2151 QKRRLRAKKLLQQSRPSIWSNLSTLQTQQQLMAVRN--------------------RAFSTTLSD 2195
            ....|   :|...:..::.:..:.:..|.:|.::.|                    |:.....|.
plant   636 DSSTL---ELSAAAAAAVMATAAAVSRQFELDSLSNGDAGSGGLHGVDSGGERISDRSIGNESSK 697

  Fly  2196 ADIALLP----QINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIK-----SLRKGASEF 2251
            :|.|:..    :|.|.::.:...:|.|::||||.|..      ....||:|     .:...|.|
plant   698 SDAAIDDVAECEILWEEITVAERIGLGSYGEVYRGDW------HGTAVAVKKFIDQDITGEALE- 755

  Fly  2252 AELLQEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLS 2316
             |...|.::|...:|.|||..:|......::|::.|.:..|.|...:.          :|...|.
plant   756 -EFRSEVRMMRRLRHPNIVLFMGAVTRPPNLSIVTEFLPRGSLYRLIH----------RPNNQLD 809

  Fly  2317 LSELLAMCIDVANGCSYLEDMH--FVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSD 2379
            ..:.|.|.:|.|.|.:||...:  .|||||...|.||       |:...||:.||||:|  .|..
plant   810 ERKRLRMALDAARGMNYLHSCNPVIVHRDLKSPNLLV-------DKNWVVKVCDFGLSR--MKVS 865

  Fly  2380 YYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVK-EG 2443
            .|...........||:||.|.:.....:.||:::||:.||:.|| |||:...|..:|:..|. :.
plant   866 TYLSSKSTAGTAEWMAPEVLRNEPADEKCDVYSYGVILWELFTL-QQPWGKMNPMQVVGAVGFQH 929

  Fly  2444 GRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQMASATADT 2500
            .||..|......:..::..||:|||..||||....::|..:...::|..:.|::|.|
plant   930 RRLDIPEFVDPGIADIIRKCWQTDPRLRPSFGEIMDSLKQLQKPIQRAAVPSSSALT 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495	8/40 (20%)
		fn3	1800..1891	CDD:394996	20/97 (21%)
		FN3	1993..2111	CDD:238020	19/125 (15%)
		PTKc_c-ros	2213..2483	CDD:270640	83/277 (30%)
AT1G18160	NP_173254.2	EDR1	154..358	CDD:433922	58/293 (20%)
		STKc_MAP3K-like	721..967	CDD:270901	82/273 (30%)