Protein Alignment sev and csk

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: NP_001071067.1
• Gene: csk / 556454
• ZFINID: ZDB-GENE-061103-493
• Length: 450
• Species: Danio rerio
• Alignment Length: 285
• Identity: 96/285 - (33%)
• Similarity: 152/285 - (53%)
• Gaps: 29/285 - (10%)

  Fly  2204 INWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASEFAELLQEAQLMSNFKHEN 2268
            :|..:|||::.:|.|.||:|..|..:      .::||:|.::..|:..| .:.||.:|:..:|.|
Zfish   190 LNRKELKLIQTIGKGEFGDVMVGDYR------GKKVAVKCIKHDATAQA-FVAEASVMTQLRHNN 247

  Fly  2269 IVCLVGICFDTE-SISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCS 2332
            :|.|:|:..:.: |:.::.|:|..|.|:.|||:...|.         :....|:...:||.....
Zfish   248 LVQLLGVIVEEKGSLYIVTEYMAKGSLVDYLRSRGRTV---------IGGDRLINFSMDVCKAME 303

  Fly  2333 YLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPE 2397
            |||..:|||||||.||.||:|.       ...|:.||||.::...:....|     |||:|.|||
Zfish   304 YLEANNFVHRDLAARNVLVSED-------NIAKVSDFGLTKEASSTQDTAK-----LPVKWTSPE 356

  Fly  2398 SLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLL 2462
            :|.:..|:|:||||::|:|.|||.:.|:.||......||:..|::|.::..|..|...:|.::..
Zfish   357 ALREKKFSTKSDVWSYGILLWEIYSFGRVPYPRIPLKEVVPRVEKGYKMDSPDGCPPVVYDIMKQ 421

  Fly  2463 CWRTDPWERPSFRRCYNTLHAISTD 2487
            ||..|...|||||.....|..|.|:
Zfish   422 CWTLDAVVRPSFRDLREKLQDIITN 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495
		fn3	1800..1891	CDD:394996
		FN3	1993..2111	CDD:238020
		PTKc_c-ros	2213..2483	CDD:270640	90/270 (33%)
csk	NP_001071067.1	SH3_CSK	11..67	CDD:212703
		SH2_csk_like	78..175	CDD:198190
		PTKc_Csk	188..443	CDD:133213	94/280 (34%)