Protein Alignment sev and zap70

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: NP_001006825.1
• Gene: zap70 / 448557
• XenbaseID: XB-GENE-956409
• Length: 609
• Species: Xenopus tropicalis
• Alignment Length: 265
• Identity: 87/265 - (32%)
• Similarity: 142/265 - (53%)
• Gaps: 27/265 - (10%)

  Fly  2215 LGSGAFGEVYEGQLKTEDSEEPQRVAIKSLR----KGASEFAELLQEAQLMSNFKHENIVCLVGI 2275
            ||||.||.|.:|..|.:..:..  ||||.|:    |...:  |:::||::|....:..||.::|:
 Frog   332 LGSGNFGCVKKGVYKLKKRQID--VAIKVLKVQDEKNVRD--EMMKEAEIMHQLDNPYIVRMIGV 392

  Fly  2276 CFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLEDMHFV 2340
            | :.|::.|:||....|.|..:|.|.:..          :.:|.::.:...|:.|..|||..:||
 Frog   393 C-EAENLMLVMEMASGGPLNKFLGAKKDV----------IPMSNIVELMHQVSIGMKYLEGKNFV 446

  Fly  2341 HRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSD-YYRKEGEGLLPVRWMSPESLVDGLF 2404
            |||||.||.|:.       .:...||.||||::.:...| ||:.:..|..|::|.:||.:....|
 Frog   447 HRDLAARNVLMV-------NQHYAKISDFGLSKALAADDSYYKAKSFGKWPLKWYAPECINYRKF 504

  Fly  2405 TTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPW 2469
            :::||||::|:..||..|.||:||......||::.::...||..|..|..::|.::|.||.....
 Frog   505 SSRSDVWSYGITMWEAFTYGQKPYKKLKGTEVMSFIERNERLACPAGCPPEMYQVMLDCWIFKME 569

  Fly  2470 ERPSF 2474
            :||:|
 Frog   570 DRPNF 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495
		fn3	1800..1891	CDD:394996
		FN3	1993..2111	CDD:238020
		PTKc_c-ros	2213..2483	CDD:270640	87/265 (33%)
zap70	NP_001006825.1	SH2_N-SH2_Zap70_Syk_like	8..111	CDD:198191
		SH2_C-SH2_Zap70	152..256	CDD:198265
		Protein Kinases, catalytic domain	321..589	CDD:473864	87/265 (33%)