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Protein Alignment sev and LYN

DIOPT Version :10

Sequence 1:	NP_511114.2	Gene:	sev / 32039	FlyBaseID:	FBgn0003366	Length:	2554	Species:	Drosophila melanogaster
Sequence 2:	NP_002341.1	Gene:	LYN / 4067	HGNCID:	6735	Length:	512	Species:	Homo sapiens

Alignment Length:	461	Identity:	126/461 - (27%)
Similarity:	203/461 - (44%)	Gaps:	137/461 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  2120 PEKRGSLVLAI-----IAPAAIVSSCVLALVLVRKVQKRRL--------RAKKLLQQSRPSIWSN 2171
            ||::|.:|:|:     |.|..:         ..:|.:|.::        :||.||.:....|.||
Human    61 PEEQGDIVVALYPYDGIHPDDL---------SFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSN 116

  Fly  2172 ----LSTLQTQQ-------------QLMAVRNRA--------------FSTTLSDAD-------- 2197
                |:||:|::             ||:|..|.|              ||.::.|.|
Human   117 YVAKLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIK 181

  Fly  2198 ---------------------------------------------IALLPQINWSQ--------- 2208
                                                         |:..||..|.:
Human   182 HYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPWDKDAWEIPRES 246

  Fly  2209 LKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASEFAELLQEAQLMSNFKHENIVCLV 2273
            :||::.||:|.||||:.|.....     .:||:|:|:.|.......|:||.||...:|:.:|.|.
Human   247 IKLVKRLGAGQFGEVWMGYYNNS-----TKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLY 306

  Fly  2274 GICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLEDMH 2338
            .:....|.|.:|.|:|..|.||.:|::...         ..:.|.:|:.....:|.|.:|:|..:
Human   307 AVVTREEPIYIITEYMAKGSLLDFLKSDEG---------GKVLLPKLIDFSAQIAEGMAYIERKN 362

  Fly  2339 FVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSPESLVDGL 2403
            ::||||...|.||:||.       ..||.||||||.|..::|..:|| ...|::|.:||::..|.
Human   363 YIHRDLRAANVLVSESL-------MCKIADFGLARVIEDNEYTAREG-AKFPIKWTAPEAINFGC 419

  Fly  2404 FTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDP 2468
            ||.:||||:||:|.:||:|.|:.||..|.|.:|:..:.:|.|:.:...|.::||.::.:||:...
Human   420 FTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEKA 484

  Fly  2469 WERPSF 2474
            .|||:|
Human   485 EERPTF 490

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.