DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment sev and Ack

DIOPT Version :10

Sequence 1:NP_511114.2 Gene:sev / 32039 FlyBaseID:FBgn0003366 Length:2554 Species:Drosophila melanogaster
Sequence 2:NP_647859.1 Gene:Ack / 38489 FlyBaseID:FBgn0028484 Length:1073 Species:Drosophila melanogaster


Alignment Length:447 Identity:128/447 - (28%)
Similarity:195/447 - (43%) Gaps:81/447 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly  2140 CVLALVLVRKVQKRRLRAKKLLQQSRPSIWSNL----STLQTQQQLMAVRNRA------FSTTLS 2194
            |.|....:|::.: .:|.|| ..|.|.:|.|.|    ....:::|..|.|..:      .:..:.
  Fly    57 CGLGKPAIRRLME-AVRKKK-AHQWRKNILSKLIGGGKQPSSKKQSSAARESSQGNGTQLTCLIH 119

  Fly  2195 DADIALLPQINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRK------GASEFAE 2253
            :.||.:       .||    ||.|:||.|..|:.....:.:...||:|.|:.      |..:  :
  Fly   120 EKDITM-------GLK----LGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIID--D 171

  Fly  2254 LLQEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLR-AARATSTQEPQPTAGLSL 2317
            ..:|.|.|....|.|:|.|.|:.. ::.:.:|.|..|.|.||..|| ..|.|           ||
  Fly   172 FFREVQAMHALDHANLVRLYGVVL-SQPMMMITELAERGSLLDTLRKQCRHT-----------SL 224

  Fly  2318 SELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLAR------DIY 2376
            :.:....:.:..|.:|||...|:||||||||.|:...       ..:|||||||.|      |.|
  Fly   225 TIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAG-------NKIKIGDFGLMRALPQEDDCY 282

  Fly  2377 KSDYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHV- 2440
            ....::|     :|..|.:||||....|:..||.|.|||..||:.:.|:.|:...|..::|..: 
  Fly   283 VMSEHKK-----VPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKID 342

  Fly  2441 KEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQ--------MASAT 2497
            :||.||.||..|...:|:::|.||...|.|||:|......|.::|..:.|..        :....
  Fly   343 REGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVMRASRSHHESKGLQIEP 407

  Fly  2498 ADTV-VSCSRPEFKVRFDGQPLEEHREHNERPEDENLTLREVPLKDKQLYANEGVSR 2553
            .||: :...|.|.|: ..||        |:|..|..:..|.:..:.|...|.:.|.|
  Fly   408 GDTIAIIDGRHELKL-IKGQ--------NQRTFDIGIFPRNLLEQRKVGAAGDVVMR 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sevNP_511114.2 fn3 439..520 CDD:394996
FN3 826..921 CDD:238020
Vgb 992..>1118 CDD:443399
LY 993..1026 CDD:214531
FN3 1292..1374 CDD:214495
fn3 1800..1891 CDD:394996
FN3 1993..2111 CDD:238020
PTKc_c-ros 2213..2483 CDD:270640 93/283 (33%)
AckNP_647859.1 SAM_TNK-like 14..75 CDD:188938 4/18 (22%)
PTKc_Ack_like 128..385 CDD:270636 94/286 (33%)
UBA_TNK1 1031..1070 CDD:270513
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.