Protein Alignment sev and R09D1.12

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: NP_496025.2
• Gene: R09D1.12 / 174501
• WormBaseID: WBGene00011168
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 103/301 - (34%)
• Similarity: 150/301 - (49%)
• Gaps: 44/301 - (14%)

  Fly  2213 RFLGSGAFGEVYEGQL-----KTEDSEEPQRVAIKSLRKGASEFAELL--QEAQLMSNF-KHENI 2269
            |.||.|.||.:.:|.|     ||.:..: ..||:|.:.....|..:.|  .|.:||... ||.|:
 Worm   130 RKLGKGKFGIINKGLLTLRICKTNEVVQ-VNVAVKKMVDPTDEKQDKLIYDEIKLMCAIGKHPNV 193

  Fly  2270 VCLVGICFDTESIS------LIMEHMEAGDLLSYLRAARATSTQE---PQPTAG----------L 2315
            :.:||.....|.:|      .:.|.:|.|||.|.||.:..|...|   .:.|.|          :
 Worm   194 LAIVGAITKKEKVSGREYNQAVSEFIEGGDLRSVLRNSPYTFQDEITSRERTGGQNVDAEVFDTI 258

  Fly  2316 SLSELLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDY 2380
            |.|:|.:....:|||..||..:..||||||.||..|       .:.:.::||||||||.....||
 Worm   259 STSDLFSFAYQIANGMEYLASLPCVHRDLALRNVFV-------KKNKIIRIGDFGLARHNGDKDY 316

  Fly  2381 YRKE--GEGLLPVRWMSPESLVDGL-FTTQSDVWAFGVLCWEILTLGQQPYAA--RNNFE----V 2436
            |:.:  .|..||:.|::||...||. ||..:|||::||..:|:.:||..||..  :|.|:    |
 Worm   317 YKVKYSPETPLPIFWLAPECFDDGTSFTEMTDVWSYGVCLFELFSLGASPYLEEFQNFFDPIYYV 381

  Fly  2437 LAHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFRRC 2477
            :|.::.|.||..|..|...:|:.:|.||.:|..:||.|.:|
 Worm   382 VAFLESGKRLSSPKYCRSDIYNFMLECWNSDAKQRPRFTKC 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495
		fn3	1800..1891	CDD:394996
		FN3	1993..2111	CDD:238020
		PTKc_c-ros	2213..2483	CDD:270640	103/301 (34%)
R09D1.12	NP_496025.2	TyrKc	127..426	CDD:197581	103/301 (34%)