Protein Alignment sev and Matk

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: XP_006513357.1
• Gene: Matk / 17179
• MGIID: 99259
• Length: 506
• Species: Mus musculus
• Alignment Length: 315
• Identity: 102/315 - (32%)
• Similarity: 162/315 - (51%)
• Gaps: 44/315 - (13%)

  Fly  2201 LPQINW----SQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQRVAIKSLRKGASEFAELLQEAQLM 2261
            |.:..|    ..|.|...:|.|.||.|.:|:..      .|:||:|:::...:..| .|.|..:|
Mouse   222 LAKAGWLLDLQHLTLGAQIGEGEFGAVLQGEYL------GQKVAVKNIKCDVTAQA-FLDETAVM 279

  Fly  2262 SNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCID 2326
            :..:|.|:|.|:|:... ..:.::|||:..|:|:::||.         :..|.:|.|:||...:.
Mouse   280 TKLQHRNLVRLLGVILH-HGLYIVMEHVSKGNLVNFLRT---------RGRALVSTSQLLQFALH 334

  Fly  2327 VANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGL--- 2388
            ||.|..|||....||||||.||.||:|..       ..|:.|||||         :.|.:||
Mouse   335 VAEGMEYLESKKLVHRDLAARNILVSEDL-------VAKVSDFGLA---------KAERKGLDSS 383

  Fly  2389 -LPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPPMC 2452
             |||:|.:||:|.:|.|:::||||:||||.||:.:.|:.||...:..||...|::|.|::.|..|
Mouse   384 RLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGC 448

  Fly  2453 TEKLYSLLLLCWRTDPWERPSFRRCYNTLHAISTDLRRTQMASATADTVVSCSRP 2507
            ...:::|:..||..:|..||.||:   .:..:..:||...:::.........|.|
Mouse   449 PGSVHTLMGSCWEAEPARRPPFRK---IVEKLGRELRSVGVSAPAGGQEAEGSAP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495
		fn3	1800..1891	CDD:394996
		FN3	1993..2111	CDD:238020
		PTKc_c-ros	2213..2483	CDD:270640	94/273 (34%)
Matk	XP_006513357.1	SH3	49..107	CDD:473055
		SH2_csk_like	117..214	CDD:198190
		Protein Kinases, catalytic domain	227..480	CDD:473864	97/288 (34%)