Protein Alignment sev and src-1

DIOPT Version :10

• Sequence 1: NP_511114.2
• Gene: sev / 32039
• FlyBaseID: FBgn0003366
• Length: 2554
• Species: Drosophila melanogaster
• Sequence 2: NP_001364829.1
• Gene: src-1 / 171722
• WormBaseID: WBGene00005077
• Length: 537
• Species: Caenorhabditis elegans
• Alignment Length: 290
• Identity: 112/290 - (38%)
• Similarity: 154/290 - (53%)
• Gaps: 27/290 - (9%)

  Fly  2197 DIALLPQINW----SQLKLLRFLGSGAFGEVYEGQLK--TEDSEEPQRVAIKSLRKGASEFAELL 2255
            |::...|.||    :||.|.|.||.|.||||:.|:.:  .|       ||||:::.|.......|
 Worm   250 DLSHDTQQNWEIPRNQLHLKRKLGDGNFGEVWYGKWRGIVE-------VAIKTMKPGTMSPEAFL 307

  Fly  2256 QEAQLMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSEL 2320
            ||||:|....|.|:|.|..:|...|...:|.|:|..|.||.|||...:|          |.:..|
 Worm   308 QEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGST----------LGIQAL 362

  Fly  2321 LAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEG 2385
            :.|...:|||..|||:...||||||.||.||.:......   .||:.||||||.:.:.|.|....
 Worm   363 VDMAAQIANGMMYLEERKLVHRDLAARNVLVGDKISGVP---VVKVADFGLARKLMEEDIYEART 424

  Fly  2386 EGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVLAHVKEGGRLQQPP 2450
            ....|::|.:||:...|.||.:||||::|:|.:||:|.||.||...:|.||:..|:.|.|:..|.
 Worm   425 GAKFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR 489

  Fly  2451 MCTEKLY-SLLLLCWRTDPWERPSFRRCYN 2479
            .|.|::| .:||.||...|..||:|...|:
 Worm   490 GCPEQIYEEVLLKCWDKTPDRRPTFDTLYH 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sev	NP_511114.2	fn3	439..520	CDD:394996
		FN3	826..921	CDD:238020
		Vgb	992..>1118	CDD:443399
		LY	993..1026	CDD:214531
		FN3	1292..1374	CDD:214495
		fn3	1800..1891	CDD:394996
		FN3	1993..2111	CDD:238020
		PTKc_c-ros	2213..2483	CDD:270640	105/270 (39%)
src-1	NP_001364829.1	SH3_Src_like	79..130	CDD:212779
		SH2_Src_family	138..240	CDD:199827
		PTKc_Src_like	270..522	CDD:270630	105/270 (39%)