DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-4 and SmydA-3

DIOPT Version :9

Sequence 1:	NP_572675.1	Gene:	SmydA-4 / 32034	FlyBaseID:	FBgn0030257	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_001260366.1	Gene:	SmydA-3 / 34502	FlyBaseID:	FBgn0262599	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	163/491 - (33%)
Similarity:	256/491 - (52%)	Gaps:	20/491 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 VEHSDIYGRYLVANRQLEAGETLIREEPLAIGPCVSGDPVCLGCYHPVSLKADQYRCPGCAWPLC 115
            |:.|.:.||||||...:.....||.|.|.|:||..:|..||||||.| :...::..|..|.||||
  Fly    14 VQWSPVCGRYLVAKGAIRGHGLLIEELPFAVGPKCNGPVVCLGCYEP-NPDPEEELCSECGWPLC 77

  Fly   116 GSTCAGLKHRHGHTETECQLYAERRAVAGELLTERAGPAEVRDLYEL--VMIVRILLLRQHDPEQ 178
             ..|| .:..:.|...||....:.||....|      |:..|...:|  :|.:|:||.::.:||:
  Fly    78 -VECA-QQADNAHFRLECSQLKDARARFFRL------PSGSRHCPQLDCIMPLRVLLAKEANPER 134

  Fly   179 F-ALIARMESHTEERRQNAVLWRHYEEKVVQRLRVTWQLEDLEAEQ-VHEVCGILDVNCFEI-GQ 240
            : ..:|.||.|.|||:::|.:|......:.|.||...||.:..:|: :.:|.|:|:||.||. ..
  Fly   135 WDNEVAPMEHHKEERQRDADVWHADRVNIAQYLRGPCQLANRFSEELIMQVVGVLEVNAFEARSP 199

  Fly   241 NGAKARTLYPSAFLLAHDCTPNTAHTDDPS-SFEILLRTSRRVREREALTLSYAYTLQGTLKRRA 304
            .|...|.|:|...:|||:|.|||:.:..|| .::|.||....:.|.:.|..||.|||.||.:|:.
  Fly   200 KGYPLRCLFPYTGILAHNCVPNTSRSIYPSEGYKIRLRAMVDLEEGQPLHHSYTYTLDGTAQRQK 264

  Fly   305 FMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRTGSVRAVDPLQQTGDWACDRCAHKMGATEVE 369
            .:.:||.|.|.|.||.||.||||..|:|.|..|..|......|.:....|.|..|.......:..
  Fly   265 HLKQGKFFTCQCERCLDPTELGTHFSSLKCGQCAEGFQVPRQPTEPDTSWNCANCGSDTSNADAL 329

  Fly   370 RQLDRINNDLEDID-----VHDIPGLENFLLRYRDVLRPNHYLLLSAKYSLCQIYGRTEGYLLPQ 429
            ..|..:.:::..:.     ...:..:|..|.:|:.:|.|.|::....:..|.::|||.:||.:.|
  Fly   330 AMLQSLQSEVNAVQALPMAAKRLEEIERLLRKYKSLLHPLHFIATGLRQLLIEMYGRVQGYEMVQ 394

  Fly   430 MSPEDIARKESYCREFLEIVDVLDPGLTRLRGLIMYELHAPVMVLAQSAFQSGQISRQEFQRRLK 494
            :....:.||...||:.|.:::..:|||:|.|.:.:||||.|:::||:|.|.:|::...|.:.||.
  Fly   395 LPDHQLERKAELCRQVLRVLNTFEPGLSRTRAMNLYELHVPLVLLAKSGFIAGKLKGGELRARLV 459

  Fly   495 EVVKLLQVSRDILLMEPEGSTENAMGQAAADALSKM 530
            :.:.||:...:||..|.:.|.|..:...|..||.::
  Fly   460 DAIDLLKECVEILEFEDKSSQEGVLCVVAKQALKQL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-4	NP_572675.1	None
SmydA-3	NP_001260366.1	SET	<207..252	CDD:250181	16/44 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I1875
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D199835at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46455
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
	6	5.970