DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SmydA-4 and set-30

DIOPT Version :9

Sequence 1:	NP_572675.1	Gene:	SmydA-4 / 32034	FlyBaseID:	FBgn0030257	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_508850.2	Gene:	set-30 / 180772	WormBaseID:	WBGene00022499	Length:	560	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	65/324 - (20%)
Similarity:	113/324 - (34%)	Gaps:	91/324 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 SHTEERRQNAVLWRHYEE------------KVVQRLR------------VTWQLEDLEAEQVHEV 227
            ::.|.:|....:|.|..:            |...|::            ||:||........|.:
Worm   117 NNRESKRSVMEIWEHCADMKKDENAMKSFKKTYDRVKQFGDTNHLMDEEVTFQLHSRNFINRHSI 181

  Fly   228 CGILDVNCFEIGQNGAKARTLYPSAFLLAHDCTPNTAHTDDPSSFEILLRTSRRVREREAL---- 288
            ..:..:.  |||:.      ||.......|.|.||..:     |...::...|.:.:...|
Worm   182 SNVDYLR--EIGKG------LYLDLCKYDHSCRPNAIY-----SCNGIVAKLRALHDNVDLENVE 233

  Fly   289 TLSYAYTLQGTLK--RRAFMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRT-----------G 340
            |..|.|......|  ||..:.|...|.|.|.||.||.:  ...::::|..|.:           |
Worm   234 TTHYTYIELPPCKIQRRHMLKETWYFECHCERCDDPDD--NWLTSVLCPVCISKTEYRKTIKLHG 296

  Fly   341 SVRAVDPLQQTGDWACDRCAHKM----------GATEVERQLDRINNDLED-IDVHDIPGLENFL 394
            .....:|  :|.:..||||:..:          |...:.|.::...::.:| |::..|  .:..|
Worm   297 PEAYANP--ETLEIVCDRCSTTLDREYIFMALDGMRTIRRTVEGAEDETKDPIELLKI--YQGAL 357

  Fly   395 LRYRDVLRPNHYLLLSAKYSLCQIYGRTEGYLLPQMSPEDIARKESY---------CREFLEIV 449
            :.|..:|.      :|..| .||:...    ::|.:|...:.:||..         |..|:..|
Worm   358 MTYERILP------MSNAY-FCQLIAA----MIPLISRVSMTKKERLVASLDLHLKCETFVRYV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SmydA-4	NP_572675.1	None
set-30	NP_508850.2	zf-MYND	41..78	CDD:366792
set-30	NP_508850.2	SET_SMYD	<179..266	CDD:380997	23/99 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D981799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2203
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820