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Protein Alignment SmydA-4 and SMYD4

DIOPT Version :9

Sequence 1:	NP_572675.1	Gene:	SmydA-4 / 32034	FlyBaseID:	FBgn0030257	Length:	532	Species:	Drosophila melanogaster
Sequence 2:	NP_443160.2	Gene:	SMYD4 / 114826	HGNCID:	21067	Length:	804	Species:	Homo sapiens

Alignment Length:	656	Identity:	133/656 - (20%)
Similarity:	204/656 - (31%)	Gaps:	240/656 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QRGGQQSKDKQEQQDKEQSPSPT------------EEKELPYRVEHS------DIYGRYLVANRQ 66
            ||...:.|.|.:::|......|.            ||.|.......|      .:.||.|||.:.
Human   188 QRNLHRLKMKMQEKDSLTESFPAALAKTLEDAALREENEQLSNASSSIGLCVDPLKGRCLVATKD 252

  Fly    67 LEAGETLIREE-------PLAIGP------------CVSGDPVCLGCY-HPVSLKADQYRCPGCA 111
            :..||.|::|:       |..:.|            ..:||..|..|. |.::    ...|.||:
Human   253 ILPGELLVQEDAFVSVLNPGELPPPHHGLDSKWDTRVTNGDLYCHRCLKHTLA----TVPCDGCS 313

  Fly   112 W-PLCGSTCA----GLKHRHGHTETECQLYAERRAVAGEL------------LTERAGPAEVRD- 158
            : ..|...|.    .|.||     |||.|       .|.|            ||...|..:||.
Human   314 YAKYCSQECLQQAWELYHR-----TECPL-------GGLLLTLGVFCHIALRLTLLVGFEDVRKI 366

  Fly   159 --------------LYELVMIVRILLLRQHDPEQ-------------------------FALIAR 184
                          |.|....|:.|.....:.|:                         |.|:..
Human   367 ITKLCDKISNKDICLPESNNQVKTLNYGLGESEKNGNIVETPIPGCDINGKYENNYNAVFNLLPH 431

  Fly   185 MESHTEERR-----QNAVLWRHYEEKVVQRL---RVTWQLEDLEAEQVHEVC------GI----- 230
            .|:|:.|.:     ..:.|.|..|...:|.:   |:. ....|:|....|:|      |:
Human   432 TENHSPEHKFLCALCVSALCRQLEAASLQAIPTERIV-NSSQLKAAVTPELCPDVTIWGVAMLRH 495

  Fly   231 -LDVNC-----FEIGQNGAK------------ARTLYPSAFLLAHDCTPNTAHTDDPSSF---EI 274
             |.:.|     ..|...|.|            |..::|...||.|.|:|||:     .||   ..
Human   496 MLQLQCNAQAMTTIQHTGPKGSIVTDSRQVRLATGIFPVISLLNHSCSPNTS-----VSFISTVA 555

  Fly   275 LLRTSRRVREREALTLSYA--YTLQGTLKRRAFMHEGKLFWC---------------------CC 316
            .:|.|:|:|:.:.:...|.  .:..|..:|:..:.....|.|                     ||
Human   556 TIRASQRIRKGQEILHCYGPHKSRMGVAERQQKLRSQYFFDCACPACQTEAHRMAAGPRWEAFCC 620

  Fly   317 RRCSDPRELGTD---CSALVC---ATCRTGSVRAVDPLQQTGDWACDRCAHKM---GATEVERQL 372
            ..|..|.: |.|   |.:..|   |..|...|..:..|||.     .|.|.|:   |  |:||.:
Human   621 NSCGAPMQ-GDDVLRCGSRSCAESAVSRDHLVSRLQDLQQQ-----VRVAQKLLRDG--ELERAV 677

  Fly   373 DRINNDLEDIDVHDIPGLENFLLRYRDVLRPNHYLLLSAKYSLCQIYGRTEGYLLPQMSPEDIAR 437
            .|::....|        .|:||.....|:..    :.......|...|             |..:
Human   678 QRLSGCQRD--------AESFLWAEHAVVGE----IADGLARACAALG-------------DWQK 717

  Fly   438 KESYCREFLEIVDVLDPGLTRLRGLIMYELHAPVMV-LAQSAFQSGQISRQEFQRRLKEVVKLLQ 501
            ..::.:..|.:|:|               .|.|..| :....|:..||....|  .:.|.:..:|
Human   718 SATHLQRSLYVVEV---------------RHGPSSVEMGHELFKLAQIFFNGF--AVPEALSTIQ 765

  Fly   502 VSRDIL 507
            .:.::|
Human   766 KAEEVL 771

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.