DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42339 and thsd7aa

DIOPT Version :9

Sequence 1:	NP_572674.3	Gene:	CG42339 / 32033	FlyBaseID:	FBgn0259241	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_009292626.1	Gene:	thsd7aa / 557991	ZFINID:	ZDB-GENE-060503-709	Length:	1702	Species:	Danio rerio

Alignment Length:	442	Identity:	89/442 - (20%)
Similarity:	167/442 - (37%)	Gaps:	116/442 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EAQLC-CN-------GRDSSCVVQKAPINAII-----EDLSD---------KPCY-CDHACLKLG 69
            |.|.| ||       |..|.|::.:..:..::     .|:.:         ..|| .|:..::..
Zfish   980 ETQYCPCNKYNAQPVGNWSDCILPEGRVEGLLGMKVQGDIKECGQGYRYQAMVCYDQDNRLVETS 1044

  Fly    70 DCCDD--FKDHCGV---LDCQVGDWGAWSECDRSCGTGMMTRNRQILQAAQNGGKHCPTLQQKRS 129
            .|...  .::.|.:   .||::.:|..||.|.:|||:|:..|::.:.:...|||:.||.|.....
Zfish  1045 RCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQ 1109

  Fly   130 CQGYRCHGHHDKKILREMALLLPAALTHNHHV----------NESGDLRHN----LRTRYRDTYK 180
            .|.|.               ::|.....:.:|          ..:.||:.|    ::||.....:
Zfish  1110 AQVYE---------------VVPCLSDCSQYVWVAEPWSVWKVSNVDLKENCGEGVQTRKVRCMQ 1159

  Fly   181 HNHD------QEYCVEFEVIKSSKACNKLP-PYN-LMTE---GDRITVRCDLEALIQDSAGSSTT 234
            :..|      ::|..:.|.:......:||| |.: ::|:   ..|..:.|::.:..|.||  |..
Zfish  1160 NTVDGPSDPVEDYLCDPEEMPLGARESKLPCPEDCVLTDWGSWSRCPLPCNVNSTRQRSA--SPI 1222

  Fly   235 ARTPQGPTTPSTT-----TVSSAASAFGQRTDDLEEERLQRET-------SSEEEATNQDGEAEE 287
            .:..:....||||     |::|....:.....|....:|....       :...:....|.::.:
Zfish  1223 RQPSERKQCPSTTEKEICTLNSNCFHYSYNITDWSTCQLSERAVCGVGFKTRMLDCVRSDSKSVD 1287

  Fly   288 ----EDEEPEQDEQDDLQNALDSDSN-ESTDYRHQRQSQMSQMSHSRRTAGK----RSAVPATPS 343
                |:...|:..|.:....::...| :.:|:     |..|:.||:...|||    |:.:.|:
Zfish  1288 LKFCEELGLEKKWQMNASCVVECPVNCQLSDW-----SSWSECSHTCGLAGKLWRRRTVIQAS-- 1345

  Fly   344 PTLPPTYHCRGEG--LAGRTTRWSALPAPSCRGKWLRLTVGPPKK-----CG 388
                     :|:|  .:.:..:|...|...| ..| |.:|..|.|     ||
Zfish  1346 ---------QGDGRPCSSQLEQWKPCPVKPC-FSW-RYSVWSPCKSEGARCG 1386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42339	NP_572674.3	Somatomedin_B	<53..79	CDD:279385	5/37 (14%)
CG42339	NP_572674.3	TSP1	86..136	CDD:214559	17/49 (35%)
thsd7aa	XP_009292626.1	TSP1	186..236	CDD:214559
		TSP1	388..440	CDD:214559
		TSP1	660..716	CDD:214559
		TSP1	1067..>1105	CDD:214559	14/37 (38%)
		TSP1	1317..1367	CDD:214559	14/65 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910