DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42339 and RSPO4

DIOPT Version :9

Sequence 1:	NP_572674.3	Gene:	CG42339 / 32033	FlyBaseID:	FBgn0259241	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_016883328.1	Gene:	RSPO4 / 343637	HGNCID:	16175	Length:	266	Species:	Homo sapiens

Alignment Length:	196	Identity:	48/196 - (24%)
Similarity:	76/196 - (38%)	Gaps:	61/196 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLLLL------LLAVILPQRQLLPFVSGGSCREAQLCC--NGRDSSC------VVQKAPINAII 51
            :.||||      :||:...::|:...: ||:|....:|.  || .|:|      .:::..|....
Human     5 LCLLLLVAHAVDMLALNRRKKQVGTGL-GGNCTGCIICSEENG-CSTCQQRLFLFIRREGIRQYG 67

  Fly    52 EDLSD-KPCYCD------HACLKLGDCCDD----------------FKDHC------GVL----- 82
            :.|.| .|.|..      :.|.|.|..|:.                :|..|      |.|
Human    68 KCLHDCPPGYFGIRGQEVNRCKKCGATCESCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNT 132

  Fly    83 -----DCQVGDWGAWSEC---DRSCGT--GMMTRNRQILQAAQNGGKHCPTLQQKRSCQGYR-CH 136
                 :|::|.||.||.|   .::||:  |:.:|.|:..:|.......|..|.:.|.|...| |.
Human   133 RECQGECELGPWGGWSPCTHNGKTCGSAWGLESRVREAGRAGHEEAATCQVLSESRKCPIQRPCP 197

  Fly   137 G 137
            |
Human   198 G 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42339	NP_572674.3	Somatomedin_B	<53..79	CDD:279385	9/48 (19%)
CG42339	NP_572674.3	TSP1	86..136	CDD:214559	17/55 (31%)
RSPO4	XP_016883328.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910