DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42339 and spon-1

DIOPT Version :9

Sequence 1:	NP_572674.3	Gene:	CG42339 / 32033	FlyBaseID:	FBgn0259241	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_495473.2	Gene:	spon-1 / 174169	WormBaseID:	WBGene00006893	Length:	819	Species:	Caenorhabditis elegans

Alignment Length:	117	Identity:	34/117 - (29%)
Similarity:	52/117 - (44%)	Gaps:	21/117 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FVSGGSCREAQLCCNGRDSSCVVQKAPINAIIEDLSDKPCYCDHACLKLGDCCDDFKDHCGVLDC 84
            |.:...|:  |:|..|.:.|  ....|.|.::||..:..             .||..:.   :||
Worm   662 FETEEECK--QICLPGYEKS--KSLIPNNQLLEDFGNTE-------------VDDGGER---VDC 706

  Fly    85 QVGDWGAWSECDRSCGTGMMTRNRQILQAAQNGGKHCPT-LQQKRSCQGYRC 135
            :|..|.||..|..|||.|..:|:|.:::.|:|||..|.. |.|:..|:...|
Worm   707 EVSKWTAWGSCSVSCGRGKKSRSRHVVKLARNGGHQCSEHLMQELQCRLRPC 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42339	NP_572674.3	Somatomedin_B	<53..79	CDD:279385	3/25 (12%)
CG42339	NP_572674.3	TSP1	86..136	CDD:214559	20/51 (39%)
spon-1	NP_495473.2	Reeler	36..171	CDD:260081
		Spond_N	197..381	CDD:283999
		TSP1	435..481	CDD:214559
		TSP1	499..551	CDD:214559
		TSP1	562..610	CDD:214559
		Kunitz_BPTI	621..672	CDD:278443	3/11 (27%)
		TSP1	708..759	CDD:214559	20/51 (39%)
		TSP1	766..816	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810