DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42339 and AgaP_AGAP012307

DIOPT Version :9

Sequence 1:	NP_572674.3	Gene:	CG42339 / 32033	FlyBaseID:	FBgn0259241	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	XP_320234.3	Gene:	AgaP_AGAP012307 / 1280387	VectorBaseID:	AGAP012307	Length:	860	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	50/252 - (19%)
Similarity:	79/252 - (31%)	Gaps:	101/252 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 CCNGRDSSCVVQKAPINAIIEDLSDK-----PCY-----CDHACLKLGDCCDDFKDHCGVLDCQV 86
            |..|:.:...:.|.|:.|...:...|     ||.     ||:...::.:......      :|:|
Mosquito   423 CGKGKQTRRRIYKHPMKAKQAECKKKLFDRRPCVGTDRDCDYNSQEIEEAYQSDP------ECEV 481

  Fly    87 GDWGAWSECDRSCGTGMMTRNRQILQAAQNGGKHC------PTLQQKRSCQGYRCHGHHDKKIL- 144
            .:||.||||...||.|..||:|:..:  :...|.|      |.|||...|. ..|.|...:.:|
Mosquito   482 TEWGPWSECSSPCGKGNKTRSRKYKK--KGARKKCERLPNPPMLQQTVPCD-EDCGGDISQPVLS 543

  Fly   145 ------------------------------------------------------REMALLLPAAL 155
                                                                  |:|...:|
Mosquito   544 SDVTIKTMAGGEGLCDANPSSSSSLACRLLQINPKCKMTQWSEWSPCSVTCGLGRKMRTRMP--- 605

  Fly   156 THNHHVNESGDLRHNLRTRYR------DTYKHNHDQ-EYCVEFEVIKSSKACNKLPP 205
                 :|:|      :||.::      |...|..|| :.|...|.::.....:.|||
Mosquito   606 -----INKS------MRTHHKRFDMGDDNDLHITDQNDPCYGVETVEEVTCGHDLPP 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42339	NP_572674.3	Somatomedin_B	<53..79	CDD:279385	5/35 (14%)
CG42339	NP_572674.3	TSP1	86..136	CDD:214559	20/55 (36%)
AgaP_AGAP012307	XP_320234.3	Reeler	24..151	CDD:280232
		Spond_N	184..371	CDD:283999
		TSP1	412..455	CDD:214559	6/31 (19%)
		TSP1	481..532	CDD:214559	20/53 (38%)
		TSP1	581..>607	CDD:214559	3/33 (9%)
		Kunitz_BPTI	662..712	CDD:278443
		TSP1	734..781	CDD:214559
		TSP1	809..856	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810