DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment C901 and dlb

DIOPT Version :9

Sequence 1:	NP_572673.1	Gene:	C901 / 32032	FlyBaseID:	FBgn0021742	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_571033.1	Gene:	dlb / 30141	ZFINID:	ZDB-GENE-980526-114	Length:	615	Species:	Danio rerio

Alignment Length:	382	Identity:	126/382 - (32%)
Similarity:	171/382 - (44%)	Gaps:	80/382 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLVTAITALKLEEMNAY---RRNFDARQSSNSNIPL---WKQ----------------------- 45
            |::.|..|...:|.:.|   :.|..:|.::...:.:   |.|
Zfish   102 LIIEAWNAESPKEHHDYTENQNNLISRLATRRRLAVGEDWSQDVHFGDQSELRYSYHVFCDEFYF 166

  Fly    46 -RACEKSQKQRQN--AHYVCDEKGDFKCLPGWQGDLCQVPMCRRGCDPMNGYCQRPGECRCRIGY 107
             .||....:.|.:  .||.|||.|:.:||.|||||.|..|:|...|...:|||:.||||:||:|:
Zfish   167 GEACSDYCRPRDDTLGHYTCDENGNKECLVGWQGDYCSDPICSSDCSERHGYCESPGECKCRLGW 231

  Fly   108 SGELCDKCIPLPGCQHGGCTKPFECICKPGWAGLFCTE--------PSCRTGCHSTRGYCEAPGE 164
            .|..|.:|:..|||.||.|::|::|:||.||.||||.:        ..|..|     ..|...|:
Zfish   232 QGPSCSECVHYPGCLHGTCSQPWQCVCKEGWGGLFCNQDLNYCTNHKPCANG-----ATCTNTGQ 291

  Fly   165 ----CRCRIGYAGRTC----SECATMPGCQHGTCN---KPLECLCLPGYTGLLCQ--TPICDPDC 216
                |.||.|:.|..|    :||...|....|:||   ....|.|..|:.|..|:  ...|..|.
Zfish   292 GSYTCTCRPGFGGTNCELEINECDCNPCKNGGSCNDLENDYSCTCPQGFYGKNCEIIAMTCADDP 356

  Fly   217 SKQHGYCRKPGE----CRCKVGWTGSQC----DKCFPYPGCANG----DCEAPWECNCHPGWGGM 269
            ....|.|.:...    |||...:|||.|    |:|...| ||||    |..|...|.|.||:.|.
Zfish   357 CFNGGTCEEKFTGGYVCRCPPTFTGSNCEKRLDRCSHKP-CANGGECVDLGASALCRCRPGFSGS 420

  Fly   270 LCDEKLTYCVEHPDTCENGGKCTSLSREDG--SYQCQCRQGFLGKNCEIRDDFLLTS 324
            .|:..:..|..:|  |:|.|.|     :||  .|.|.|..||.||||.:|.|..||:
Zfish   421 RCETNIDDCARYP--CQNAGTC-----QDGINDYTCTCTLGFTGKNCSLRADACLTN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
C901	NP_572673.1	DSL	<56..79	CDD:302925	13/24 (54%)
C901	NP_572673.1	EGF_CA	280..315	CDD:238011	15/36 (42%)
dlb	NP_571033.1	MNNL	21..75	CDD:284966
		DSL	141..203	CDD:279722	18/61 (30%)
		EGF_CA	270..308	CDD:238011	9/42 (21%)
		EGF_CA	311..346	CDD:238011	10/34 (29%)
		EGF_CA	392..423	CDD:238011	12/31 (39%)
		EGF_CA	425..460	CDD:238011	15/41 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910