Protein Alignment Rab9Fb and RAB1B

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_112243.1
• Gene: RAB1B / 81876
• HGNCID: 18370
• Length: 201
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 92/212 - (43%)
• Similarity: 133/212 - (62%)
• Gaps: 14/212 - (6%)

  Fly     3 QYDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDE 67
            :||||||:|::||.||||||||:||:|:.:||.::.|:|:||::|.:||.|:.:.||||||||.|
Human     4 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68

  Fly    68 RFKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRM 132
            ||:::..|||||||||::|||:|..:|:.|:..||:||.|.:||:||.:|||||.|....:.|..
Human    69 RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDN 133

  Fly   133 EQGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEPI 197
            .....:|:...:.|.|.|||:..||...|..::..|..|:   .|...|||:  ....:....|:
Human   134 TTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRM---GPGAASGGE--RPNLKIDSTPV 193

  Fly   198 NLAGKDRQRAKDSNTCC 214
            ..||         ..||
Human   194 KPAG---------GGCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	77/156 (49%)
RAB1B	NP_112243.1	Rab1_Ypt1	7..172	CDD:206661	80/164 (49%)
		Switch 1. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	30..45		5/14 (36%)
		Switch 2 region, required for interaction with REP1/CHM	64..83		12/18 (67%)
		Switch 2. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	65..80		8/14 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		7/37 (19%)