Protein Alignment Rab9Fb and RAB6A

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002860.2
• Gene: RAB6A / 5870
• HGNCID: 9786
• Length: 208
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 73/204 - (35%)
• Similarity: 112/204 - (54%)
• Gaps: 22/204 - (10%)

  Fly     8 FKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDERFKSL 72
            ||::.||:..|||:.|:.||..:.|...:..|:|:||..:.:.|..|.:.||:|||||.|||:||
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSL 78

  Fly    73 LPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRMEQGFN 137
            :|||.|.:...::|||||:..||:....|:.::|......|.:||||||.|..|.|||.:|:|..
Human    79 IPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGER 143

  Fly   138 YANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTA----------EP 192
            .|....:.|.|.|||:|.||..:|..::..            |.|.:.|:|.:          :|
Human   144 KAKELNVMFIETSAKAGYNVKQLFRRVAAA------------LPGMESTQDRSREDMIDIKLEKP 196

  Fly   193 PDEPINLAG 201
            .::|::..|
Human   197 QEQPVSEGG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	66/156 (42%)
RAB6A	NP_002860.2	Rab6	14..174	CDD:206654	66/171 (39%)
		Switch 1. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	32..50		5/17 (29%)
		Switch 2. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	69..88		12/18 (67%)