Protein Alignment Rab9Fb and RAB3B

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002858.2
• Gene: RAB3B / 5865
• HGNCID: 9778
• Length: 219
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 76/193 - (39%)
• Similarity: 116/193 - (60%)
• Gaps: 3/193 - (1%)

  Fly     4 YDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDER 68
            :||:||:|::|:..|||:..|.|::|:.||...|.|||:||:|:.|....:.|.||||||||.||
Human    19 FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQER 83

  Fly    69 FKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRME 133
            ::::..:|||||.|.:|:||||:.:||..:..|..:|:..|.::..|:|||||||..:.|.|..|
Human    84 YRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTE 148

  Fly   134 QGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRL---VIHTPNRLSGGQETEDTAEPP 193
            :|...|......|:|.|||...:|...|..|...|.:::   :...|:.|...:.|..:..||
Human   149 KGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTPP 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	67/156 (43%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	69/163 (42%)
		Switch 1. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	45..58		6/12 (50%)
		Switch 2. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	78..96		9/17 (53%)