Protein Alignment Rab9Fb and RAB2A

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 80/182 - (43%)
• Similarity: 117/182 - (64%)
• Gaps: 3/182 - (1%)

  Fly     4 YDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDER 68
            |.||||.:::||.||||||||::|:|.||...|..|:|::|..|.:.:.|:.:.||||||||.|.
Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    69 FKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRME 133
            |:|:..||||||.|.|||||||...:|.::..||::.|:.|:.::.:||:|||.|....|:|:.|
Human    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   134 QGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRL---VIHTPNRLSG 182
            :|..:|....|.|.|.|||:.:||.:.|...:..||.::   |....|..:|
Human   133 EGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANG 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	72/156 (46%)
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	80/182 (44%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		9/15 (60%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		2/4 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		5/8 (63%)