Protein Alignment Rab9Fb and RAB1A

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_004152.1
• Gene: RAB1A / 5861
• HGNCID: 9758
• Length: 205
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 93/212 - (43%)
• Similarity: 135/212 - (63%)
• Gaps: 13/212 - (6%)

  Fly     3 QYDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDE 67
            :||||||:|::||.||||||||:||:|:.:||.::.|:|:||::|.:||.|:.:.||||||||.|
Human     7 EYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71

  Fly    68 RFKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRM 132
            ||:::..|||||||||::|||:|..:||.|:..||:||.|.:||:||.:|||||||....:.|..
Human    72 RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDY 136

  Fly   133 EQGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEPI 197
            .....:|:...:.|.|.|||:..||...|..::..|..|:   .|...:||.| :...:....|:
Human   137 TTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRM---GPGATAGGAE-KSNVKIQSTPV 197

  Fly   198 NLAGKDRQRAKDSNTCC 214
            ..:|         ..||
Human   198 KQSG---------GGCC 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	79/156 (51%)
RAB1A	NP_004152.1	Rab1_Ypt1	10..175	CDD:206661	82/164 (50%)
		Switch 1. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL	34..48		4/13 (31%)
		Switch 2. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL	66..83		10/16 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..205		6/36 (17%)