Protein Alignment Rab9Fb and RAB25

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_065120.2
• Gene: RAB25 / 57111
• HGNCID: 18238
• Length: 213
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 76/211 - (36%)
• Similarity: 118/211 - (55%)
• Gaps: 9/211 - (4%)

  Fly     4 YDYLFKILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDER 68
            |:::||::::|:.||||:.||.||:.|.|:.....|:|::|..|.|.|....|..|||||||.||
Human     9 YNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAGLER 73

  Fly    69 FKSLLPSYYRGAHGILLVYDITSSKSFRNIDGWLKEIRRMSSESVNVMLVGNKCDDLDNRQVRME 133
            ::::..:|||||.|.|||:|:|..:::..::.||||:...:..::.|||||||.|....|:|..|
Human    74 YRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREVPTE 138

  Fly   134 QGFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEPIN 198
            :...:|.:..|.|.|.||....||...|..:...|:.::.....|.:.....|..:|:...||
Human   139 EARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQRQNSIRTNAITLGSAQAGQEP-- 201

  Fly   199 LAGKDRQRAKDSNTCC 214
              |...:||     ||
Human   202 --GPGEKRA-----CC 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	64/156 (41%)
RAB25	NP_065120.2	Rab11_like	11..174	CDD:206660	64/162 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	35..49		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	67..84		8/16 (50%)