Protein Alignment Rab9Fb and RAB7B

DIOPT Version :10

• Sequence 1: NP_727472.1
• Gene: Rab9Fb / 32029
• FlyBaseID: FBgn0052670
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_796377.3
• Gene: RAB7B / 338382
• HGNCID: 30513
• Length: 199
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 69/210 - (32%)
• Similarity: 110/210 - (52%)
• Gaps: 24/210 - (11%)

  Fly     9 KILVLGDIGVGKSCLLMRFSDNRFTEKHVCTVGMDFRVRNVELAGRMVMLQIWDTAGDERFKSLL 73
            |::::|.|||||:.||.::....|.|::..|:|.....:.:.|....:.||||||.|.|||:|::
Human    10 KLIIVGAIGVGKTSLLHQYVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTGGQERFRSMV 74

  Fly    74 PSYYRGAHGILLVYDITSSKSFRNIDGW----LKEIRRMSSESVNVMLVGNKCDDLDNRQVRMEQ 134
            .::|:|:.|.:|.:|:|..:||..:|.|    |.:|..| .:|..::|:|||. ||.:|:|..|.
Human    75 STFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPM-EQSYPMVLLGNKI-DLADRKVPQEV 137

  Fly   135 GFNYANHRALGFYEVSAKSGANVNDVFNMLSVGIYNRLVIHTPNRLSGGQETEDTAEPPDEPINL 199
            ...:...:.:.::|||||:..||...|.||:....:|......|.|     ||.....||:
Human   138 AQGWCREKDIPYFEVSAKNDINVVQAFEMLASRALSRYQSILENHL-----TESIKLSPDQ---- 193

  Fly   200 AGKDRQRAKDSNTCC 214
               .|.|      ||
Human   194 ---SRSR------CC 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Fb	NP_727472.1	Rab	8..165	CDD:206640	57/159 (36%)
RAB7B	NP_796377.3	Rab	9..169	CDD:206640	58/160 (36%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51149	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51149	67..82		6/14 (43%)