Protein Alignment Myo10A and XIE

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_175858.1
• Gene: XIE / 841898
• AraportID: AT1G54560
• Length: 1529
• Species: Arabidopsis thaliana
• Alignment Length: 1169
• Identity: 369/1169 - (31%)
• Similarity: 559/1169 - (47%)
• Gaps: 228/1169 - (19%)

  Fly   154 SSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPL 218
            :.||:|||.|..|||..:|.||::||:...|||:.|:||||:||::..|..|...:.:||.|.|.
plant    64 AGGVDDMTKLSYLHEPGVLQNLKIRYELNEIYTYTGNILIAINPFQRLPHIYDAHMMQQYKGAPF 128

  Fly   219 GSLPPHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSA---SAVI 277
            |.|.||:||:...|:.|:   .....:::|||||:||||:||::|:|||.:   ||.|   ...:
plant   129 GELSPHVFAVADVAYRAMINEGKSNSILVSGESGAGKTETTKMLMRYLAYL---GGRAVTEGRTV 190

  Fly   278 TEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQYLLEKSRIVTQAPGER 341
            .:|:||:.|:|||||||:|.||:|||||||::|:.| |.|.|.||.:..||||:||:...:..||
plant   191 EQQVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFDKQGRISGAAVRTYLLERSRVCQISDPER 255

  Fly   342 NYHVFYELLGGLSETERSKYGLLEADKYFYLNQ-------GATDCASGRVDWESLQGAMQVLGVS 399
            |||.|| ||....:.|..||.|.....:.||||       |.:|..    |:.:.:.||.::|:|
plant   256 NYHCFY-LLCAAPQEELEKYKLGHPKTFHYLNQSKCFELVGISDAH----DYIATRRAMDIVGMS 315

  Fly   400 EGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSDA--------EIKWAAHLLHISADGLH 456
            |.|:|.|.||:||:||||||.|        .:|.||.|..        .:...|.||......|.
plant   316 EKEQEAIFRVVAAILHLGNVEF--------TKGKEVDSSVPKDDKSKFHLNTVAELLMCDVKALE 372

  Fly   457 RALTSRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISIL 521
            .||..|......|.:...|....||.:||..||.:|:.||:|||.:||..:.:..| ....|.:|
plant   373 DALCKRVMVTPEEVIKRSLDPQSALISRDGLAKTIYSRLFDWLVEKINVSIGQDAT-SRSLIGVL 436

  Fly   522 DIFGFEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAK 586
            ||:|||....|||||.|||:.||.||.:||:||||:||.||.:|.::|:.:.:.||..|:.|:.|
plant   437 DIYGFESFKTNSFEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEAIDWSYIEFVDNQDVLDLIEK 501

  Fly   587 KPVGICHLLDDESNFPRATDLSFLEKCHYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLD 651
            ||.||..|||:...||::|..:|..|.:......:.:.:|::...:|.|.||||:|.|..|.|||
plant   502 KPGGIVALLDEACMFPKSTHETFANKLYQTFKTHKRFIKPKLSRTDFAVAHYAGEVQYQSDLFLD 566

  Fly   652 KNRDALRGDVLELLASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSL 716
            ||:|.:..:..:||.:|:.|.|..|...|..:               .:...:..::.:||...|
plant   567 KNKDYVIPEHQDLLGASKCPFVVGLFPPLPEE---------------TSKSSKFSSIGSRFKLQL 616

  Fly   717 QQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVE 781
            |||::::....|.::||:|||........:...::||||..|:|:.|:|...|||.|..|..|:.
plant   617 QQLMETLNSTEPHYIRCVKPNNLLKPAVFENVNIMQQLRCGGVLEAIRISCAGYPTRKPFFEFIN 681

  Fly   782 RYRHLLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLR------------------ 828
            |:..|.|..|......:...:.:|:   ..|::|  ||:|.|:||||
plant   682 RFGLLYPRALEGNYEEKAAAQKILD---NIGLKG--YQVGKTKVFLRAGQMAELDARRTMVLSAA 741

  Fly   829 -EALHRALESGRTER----LRRAAVSVQRHVRGML-------VRRQLA----------------- 864
             :.:.|.:.:.:.:|    ||:|.:|:|...||.|       :|||.|
plant   742 AKKIQRRIRTHQAQRRFILLRKATISLQALCRGRLSSKIFDNLRRQAAAVKIQKNARRLHSRKSY 806

  Fly   865 -------------------------RRQA-AATRLQARWRGQRAQQRYERLRKGALTAQRLWRGR 903
                                     |:|. |||.:||::|..||...:::|:||.:.:|..|||:
plant   807 KNLHVAALVVQTGLRAMAAHKQFRFRKQTKAATTIQAQFRCHRATLYFKKLKKGVILSQTRWRGK 871

  Fly   904 QARRRVQQLRSDHRRRQEAREAAQRAREAREAK-QAVLERSQL---SYLDIPAELAFIYSKLQGW 964
            .|||.::||:...|.....:|    |::..|.| :.:..|:||   |.:|:..|......|||
plant   872 LARRELRQLKMASRETGALKE----AKDMLEKKVEELTYRAQLEKRSRVDLEEEKNQEIKKLQ-- 930

  Fly   965 SPPHGDRHLVKVLGTVPGPPSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITA-----PLL 1024
                                ||..::.:.:.:          .|||.::.|.....|     |::
plant   931 --------------------SSLEEMRKKVDE----------TNGLLVKEREAAKKAIEEAPPVV 965

  Fly  1025 TRA---------------------ASRDQDFQ---DALAVFKLILRWSND--KALEGAKEKL--L 1061
            |..                     |:.:|:.|   ||...|......|.|  |.||..::|.  |
plant   966 TETQVLVEDTQKIEALTEEVEGLKANLEQEKQRADDATRKFDEAQESSEDRKKKLEDTEKKAQQL 1030

  Fly  1062 ADYIVHKALSSRGLRDEILVQLCNQVHGLPPN---SGEATRLWQL---LGQCLCCFQPSA----- 1115
            .:.:.........|..|..| |..|...:.||   ||.:..:.|.   .|......:||.
plant  1031 QESVTRLEEKCNNLESENKV-LRQQAVSIAPNKFLSGRSRSILQRGSESGHLSVDARPSLDLHSH 1094

  Fly  1116 AFSKYLMRFVDDEAPESL-------RPLLLRQLLRQQGGGTSSGAVGAGACRSFVPAWLEWRAW 1172
            :.::..:..|||:..:||       :.||:|.:::..|   ..|.....||..: ...|:||::
plant  1095 SINRRDLSEVDDKPQKSLNEKQQENQELLIRCIVQHLG---FQGKRPVTACIIY-KCLLQWRSF 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	258/680 (38%)
		PTZ00121	<828..>943	CDD:173412	42/188 (22%)
		MyTH4	1014..1171	CDD:470587	44/207 (21%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
XIE	NP_175858.1	COG5022	12..1406	CDD:227355	369/1169 (32%)
		MYSc_Myo11	79..723	CDD:276835	258/680 (38%)
		Myo5-like_CBD	<1330..1492	CDD:470793