Protein Alignment Myo10A and VIIIA

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_175453.2
• Gene: VIIIA / 841458
• AraportID: AT1G50360
• Length: 1153
• Species: Arabidopsis thaliana
• Alignment Length: 979
• Identity: 345/979 - (35%)
• Similarity: 508/979 - (51%)
• Gaps: 138/979 - (14%)

  Fly    35 VQALIKGKMRIVRFHLEPWQRGGGGSVTPSPAQSPSLALLSPHVLRRQRPASLEDFEDLPNLSAK 99
            |::::.|:...:         |.|.|:.|.| :|........:|..|::  .|:.:..|||.:.
plant    67 VRSILNGERSSI---------GDGDSILPLP-ESNDRKWSDTNVYARKK--VLQFWVQLPNGNW- 118

  Fly   100 HPALPSSRLRRLKCRYPQVVKRLSTLCSD--VIARHPQTFALQPGEGSLRARQDLGSSGVEDMTL 162
                             ::.|.:||...:  ::....:...:: .|..:.|..|: ..||:|:..
plant   119 -----------------ELGKIMSTSGEESVIVVTEGKVLKVK-SETLVPANPDI-LDGVDDLMQ 164

  Fly   163 LDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGSLPPHLFA 227
            |..|:|.::|:||..||::.:|||.||.:|:||||:|..| .||....:.|..|...|  ||::|
plant   165 LSYLNEPAVLYNLEYRYNQDMIYTKAGPVLVAVNPFKEVP-LYGNRNIEAYRKRSNES--PHVYA 226

  Fly   228 IGAAAHAALPSPQV---VVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQILEAAPLLE 289
            |...|...:...:|   ::||||||:||||:.|:.||||||:  ||||.   |..:||:..|:||
plant   227 IADTAIREMIRDEVNQSIIISGESGAGKTETAKIAMQYLAAL--GGGSG---IEYEILKTNPILE 286

  Fly   290 AFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQYLLEKSRIVTQAPGERNYHVFYELLGGL 353
            |||||:|.||||||||||.:|::| ::|.|.||:|..:||||||:|....|||:||:||:|..|.
plant   287 AFGNAKTLRNDNSSRFGKLIEIHFSETGKISGAQIQTFLLEKSRVVQCTEGERSYHIFYQLCAGA 351

  Fly   354 SETERSKYGLLEADKYFYLNQGATDCAS-GRVD----WESLQGAMQVLGVSEGEREGIVRVLAAV 413
            |.|.|.|..|..|.:|.||.|  ::|.| ..||    :.:::.|:.::.||:.::|.:..:||||
plant   352 SPTLREKLNLTSAKQYNYLKQ--SNCYSINGVDDAERFHAVKEALDIVHVSKEDQENVFAMLAAV 414

  Fly   414 LHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHTPLGID 478
            |.||||.|   .:...:..||...|..:...|.|:..:.:.|..||:.|......:.:...|.:.
plant   415 LWLGNVSF---TIIDNENHVEPEPDESLSTVAKLIGCNINELKLALSKRNMRVNNDTIVQKLTLS 476

  Fly   479 QALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENSFEQLCINYAN 543
            ||:|||||.||::||.||:|||.:||..:..|.......||||||:|||...:|||||.||||||
plant   477 QAIDARDALAKSIYACLFDWLVEQINKSLAVGKRRTGRSISILDIYGFESFNKNSFEQFCINYAN 541

  Fly   544 ENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFPRATDLS 608
            |.||.:||:|:|||||.||.::.::||.:.::||...:.|..|||:|:..|||:||.||..|||:
plant   542 ERLQQHFNRHLFKLEQEEYIQDGIDWTRVDFEDNQECLSLFEKKPLGLLSLLDEESTFPNGTDLT 606

  Fly   609 FLEKC--HYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLAS---- 667
            ...|.  |.|.  :..:...|  .:.|.|.||||:|.|...|||:||||.|..|.::||:|
plant   607 LANKLKQHLND--NSCFRGDR--GKAFTVAHYAGEVTYETTGFLEKNRDLLHSDSIQLLSSCSCH 667

  Fly   668 ------------SRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQQLL 720
                        |..||||.|.|       ||     |::.:.:       :||.:|...|.||:
plant   668 LPQAFASSMLIYSEKPLVGPLHK-------AG-----GADSQRL-------SVATKFKGQLFQLM 713

  Fly   721 QSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRH 785
            |.:|...|.|:||||||..:.|...:...||||||..|:|:.::|.:.|:|.|:....|..||..
plant   714 QRLGNTTPHFIRCIKPNNVQSAGLYEQGLVLQQLRCCGVLEVVRISRSGFPTRMFHHKFARRYGF 778

  Fly   786 LLPSPLARGTPYRELCRALL---EAMPRTGVEGPDYQLGATRVFLREALHRALESGRTERLRRAA 847
            ||...:|...|. .:..|:|   ..:|..      ||:|.|::|.|......||..|
plant   779 LLLENIAAKDPL-SVSVAILHQFNILPEM------YQVGYTKLFFRTGQIGVLEDTR-------- 828

  Fly   848 VSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQARRRVQQL 912
               .|.:.|:|             |||:.:||.:|:.|.:.|:.|....|...||.:.|:...:|
plant   829 ---NRTLHGIL-------------RLQSYFRGHQARCRLKELKTGITILQSFVRGEKMRKEYTEL 877

  Fly   913 RSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHG------DR 971
            ...||.....:...:| |.|.:..:|.::.|.:....|..||....:...||....|      |.
plant   878 LQRHRASAAIQSHVKR-RIASQQYKATVDASAVIQSAIRGELVRRCAGDIGWLSSGGTKRNESDE 941

  Fly   972 HLVK 975
            .|||
plant   942 VLVK 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	281/688 (41%)
		PTZ00121	<828..>943	CDD:173412	27/114 (24%)
		MyTH4	1014..1171	CDD:470587
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
VIIIA	NP_175453.2	MYSc_Myo8	171..817	CDD:276834	281/688 (41%)
		MAD	848..>1029	CDD:461677	25/99 (25%)