Protein Alignment Myo10A and MYA1

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_173201.2
• Gene: MYA1 / 838333
• AraportID: AT1G17580
• Length: 1520
• Species: Arabidopsis thaliana
• Alignment Length: 1028
• Identity: 336/1028 - (32%)
• Similarity: 506/1028 - (49%)
• Gaps: 166/1028 - (16%)

  Fly   154 SSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPL 218
            |.||:|||.|..|||..:|.||..||:...|||:.|:|||||||::..|..|..::.:||.|..|
plant    58 SGGVDDMTKLSYLHEPGVLRNLETRYELNEIYTYTGNILIAVNPFQRLPHIYETDMMEQYKGIAL 122

  Fly   219 GSLPPHLFAIGAAAHAALPSP---QVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQ 280
            |.|.||:||||.||:.|:.:.   ..:::|||||:||||:||::|:|||.:....|.....:.:|
plant   123 GELSPHVFAIGDAAYRAMINEGKNNSILVSGESGAGKTETTKMLMRYLAFLGGRSGVEGRTVEQQ 187

  Fly   281 ILEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQYLLEKSRIVTQAPGERNYH 344
            :||:.|:|||||||:|.||:|||||||::|:.| |:|.|.||.|..||||:||:...:..|||||
plant   188 VLESNPVLEAFGNAKTLRNNNSSRFGKFVEIQFDKNGRISGAAIRTYLLERSRVCQISDPERNYH 252

  Fly   345 VFYELLGGLSETERSKYGLLEADKYFYLNQGA------TDCASGRVDWESLQGAMQVLGVSEGER 403
            .|| ||......:..||.|....|:.||||.:      .|.||   ::...:.||.|:|:|..|:
plant   253 CFY-LLCAAPPEDIKKYKLENPHKFHYLNQSSCYKLDGVDDAS---EYLETRRAMDVVGISNEEQ 313

  Fly   404 EGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSD--------AEIKWAAHLLHISADGLHRALT 460
            |.|.||:||:|||||:.|.:        |.|:.|.        :.:..||.||..:|..|..||.
plant   314 EAIFRVVAAILHLGNIDFGK--------GEEIDSSVIKDKDSRSHLNMAAELLMCNAQSLEDALI 370

  Fly   461 SRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFG 525
            .|......|.:...|..|.|:.:||..||.:|:.||:|:|::||:.:.: .......|.:|||:|
plant   371 RRVMVTPEEIITRTLDPDNAIASRDTLAKTIYSHLFDWIVNKINTSIGQ-DPRSKSIIGVLDIYG 434

  Fly   526 FEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVG 590
            ||....|||||.|||:.||.||.:||:||||:||.||.:|.:.|:.:.:.||..|:.|:.|||.|
plant   435 FESFKCNSFEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEEIAWSYIEFIDNQDVLELIEKKPGG 499

  Fly   591 ICHLLDDESNFPRATDLSFLEKCHYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRD 655
            |..|||:...||::|..:|.:|........|.:|:|::...:|.::||||:|.|..:.|:|||:|
plant   500 IISLLDEACMFPKSTHETFSQKLFQTFKEHERFAKPKLSRTDFTISHYAGEVTYQSNHFIDKNKD 564

  Fly   656 ALRGDVLELLASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQQLL 720
            .:..:...|..:|....|..|...|  ..|:.::             .:..::.:||...|..|:
plant   565 YIVAEHQALFTASNCKFVAGLFHAL--HEDSSRS-------------SKFSSIGSRFKQQLHSLM 614

  Fly   721 QSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRH 785
            :|:....|.::||||||........:...|:.|||..|:|:.|:|...|||.||.|..|::|:..
plant   615 ESLNGTEPHYIRCIKPNNVLKPGIFENFNVIHQLRCGGVLEAIRISCAGYPTRLAFYDFLDRFGL 679

  Fly   786 LLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLREALHRALESGRTE--------- 841
            |.|..|......:..|:.:|:....|     |||:|.|::|||......|::.|.|
plant   680 LAPEVLEGNYDDKVACQMILDKKSLT-----DYQIGKTKIFLRAGQMAELDARRAEVLGNAARVI 739

  Fly   842 --------------RLRRAAVSVQRHVRGMLVRR------------------------------- 861
                          .:|.||:.:|..:||.:.|.
plant   740 QRQFRTCMARKNYRSIRNAAIVLQSFLRGEIARAVHKKLRIEAAALRVQKNFRRYVDRKSFVTTR 804

  Fly   862 -------------------QLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQARR 907
                               :|.|::.||..|||.|||::|...|.||:|.|:..|..||.|.|||
plant   805 SSTIVLQTGLRAMIARSEFRLRRQRKAAIVLQAHWRGRQAFSYYTRLQKAAIVTQCAWRCRLARR 869

  Fly   908 RVQQLRSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHGDRH 972
            .::.|:...|.....::|..:..:..|.....|...:....|:........:|||  ...|..|.
plant   870 ELRMLKMAARDTGALKDAKNKLEQRVEELSLRLHLEKRLRTDLEEAKVQEVAKLQ--EALHTMRL 932

  Fly   973 LVKVLGTVPGPPSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPLLTRAASRDQDFQDA 1037
            .:|       ..::.|...::..:.:..:.|||         .:||:..        .|.:..|:
plant   933 QLK-------ETTAMVVKEQEAARVAIEEASSV---------NKEPVVV--------EDTEKIDS 973

  Fly  1038 LAVFKLILRWSNDKALEGAKEKLLADYIVHKALSSRGLRDEILVQ---LCNQV 1087
            |         ||:  ::..|..|.::  .|||..::......|||   ||.::
plant   974 L---------SNE--IDRLKGLLSSE--THKADEAQHAYQSALVQNEELCKKL 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	258/676 (38%)
		PTZ00121	<828..>943	CDD:173412	39/187 (21%)
		MyTH4	1014..1171	CDD:470587	17/77 (22%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
MYA1	NP_173201.2	Myosin_N	8..47	CDD:460670
		MYSc_Myo11	73..717	CDD:276835	258/676 (38%)
		sbcc	<718..>1117	CDD:129705	66/335 (20%)
		COG1340	<868..1047	CDD:440951	35/185 (19%)
		MyosinXI_CBD	1099..1486	CDD:271259