Protein Alignment Myo10A and myo1hb

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: XP_073808376.1
• Gene: myo1hb / 796782
• ZFINID: ZDB-GENE-070705-355
• Length: 1090
• Species: Danio rerio
• Alignment Length: 925
• Identity: 325/925 - (35%)
• Similarity: 482/925 - (52%)
• Gaps: 125/925 - (13%)

  Fly    71 LALLSPHVLRRQRPASLED---FEDLPNLSAKHPALPSSRLRRLKCRYPQ----VVKRLSTLCSD 128
            ::|:|   ||...|..|.:   :|:...|..|:|.|......:..|...:    :.|.|...|..
Zfish     1 MSLIS---LRIACPVRLYERFVYENSRTLKKKYPILYQESAVKHVCGAAELSDCINKSLEERCQR 62

  Fly   129 VIARHPQTFALQPGEGSLRARQDLGSSGVEDMTLLDD-LHEASLLWNLRLRYDKGLIYTFAGSIL 192
            :         ||..||||.||..:   |::|..|||. ..|.:.:.||:.|:::.||||:.|::|
Zfish    63 I---------LQEMEGSLTARDRV---GIQDFVLLDAYTSETAFMDNLKKRFNENLIYTYIGTLL 115

  Fly   193 IAVNPYKMFPDAYGLEVAKQ---YAGRPLGSLPPHLFAIGAAAHAAL---PSPQVVVISGESGSG 251
            ::|||||    ..|:...||   |.|.....||||:||:....:..:   .|...::||||||:|
Zfish   116 VSVNPYK----ELGIYTKKQMDIYMGVNFFELPPHIFALADNVYRTMISETSNHFILISGESGAG 176

  Fly   252 KTESTKLVMQYLAAVVPGGGSASAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KS 315
            |||::|.|:|:.|...|.......| .:::|.:.|:|||||||:|.:||||||||||:::.| ..
Zfish   177 KTEASKKVLQFYAVSCPSTRLLDNV-RDRLLLSNPVLEAFGNAKTLKNDNSSRFGKYMDIQFDHQ 240

  Fly   316 GAIVGAKITQYLLEKSRIVTQAPGERNYHVFYELLGGLSETERSKYGLLE--ADKYFYLNQGATD 378
            ||.||..|..|||||||:|.|..||||:|:||:|:.| .|.|..::..||  ...|.||.||  :
Zfish   241 GAAVGGHILSYLLEKSRVVHQNHGERNFHIFYQLVEG-GEDELLRWLGLERNCQSYRYLIQG--E 302

  Fly   379 CA-----SGRVDWESLQGAMQVLGVSEGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSD 438
            ||     :.:.||:::|.|:.::..||.:.|.:..::|:|||||||:|...    .|....:.|.
Zfish   303 CAKVSSINDKSDWKTVQKALTIIEFSEKDIEHLFAIIASVLHLGNVHFEAT----FQGYARLNSS 363

  Fly   439 AEIKWAAHLLHISADGLHRALTSRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRI 503
            .||.|.:.||.|.:|.|...||.|..||:||.:.:|...:.|..||||.|||:|...|:|||::|
Zfish   364 GEIHWLSKLLGIPSDMLQEGLTHRKIEAKAEEVLSPFTAEHAKYARDALAKAIYGRTFSWLVNKI 428

  Fly   504 N-SIVQKGGTHDAHRISILDIFGFEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERL 567
            | |:..|..|... .|.:|||:|||....|||||.|||:.||.||..|.:...|.||.||..|.:
Zfish   429 NESLANKDSTRKT-VIGLLDIYGFEVFDVNSFEQFCINFCNEKLQQLFIQLTLKSEQEEYEMEGI 492

  Fly   568 EWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFP-RATDLSFLEKC--------HY-NHALSEL 622
            ||.|:.:.:|..:..|:.:|..||..:||:|...| .|||.:||||.        |: .|.|::.
Zfish   493 EWEPVPYFNNKIICDLVEEKHRGIISVLDEECLRPGEATDFTFLEKLEGKMSGHPHFVTHKLADQ 557

  Fly   623 YARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLASSRLPLVGELTKQLRAQRDAG 687
            ..|..:...:|.:.||||:|.|.|.||||||.|.|..::.|::..|:..::......:.
Zfish   558 KTRKTLERGDFRLLHYAGEVTYSVVGFLDKNNDLLYRNIKEVMRQSKNSIIQHCFHTIE------ 616

  Fly   688 KTLPKGSNGRFVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQ 752
               |.|        |.|..|||.:|.:||..|.:.:....||:|||:|||..|...|.|...|..
Zfish   617 ---PDG--------KKRPETVATQFKNSLAGLTEILMTKEPWYVRCLKPNHCKQPDRFDDVMVRH 670

  Fly   753 QLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRHLLPS--PLARGTPYRELCRALLEAMPRTGVEG 815
            |::|||:::.:::|:.|:..|.|::.|::||:.|.|.  |..:|||...:.|.:    ...|.:.
Zfish   671 QVKYLGLMEHLRVRRAGFAYRRRYEVFLKRYKALCPDTWPHWKGTPAEGVQRLI----KHLGYKT 731

  Fly   816 PDYQLGATRVFLREALHRALESGRTERLRRAAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQ 880
            .:|::|.|::|:|..        ||......|..|.:|              ..|||:||:::|.
Zfish   732 DEYKMGRTKIFIRHP--------RTLFATEDAFEVCKH--------------ELATRIQAKYKGY 774

  Fly   881 RAQQRYERLRKGALTAQRLWRGRQARRRVQQLRSDHRRRQEAREAAQRAREAREAKQAV---LER 942
            |.:..|.|.|:.|...:..|||.|||                ||..:||...:..|:.:   :.|
Zfish   775 RVKGDYLRQREAATKIETCWRGLQAR----------------RERERRAWAVKVIKKFIKGFMNR 823

  Fly   943 SQLSYLDIPAELAFI 957
            :|...:|....|||:
Zfish   824 NQPVSMDNSEYLAFV 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	262/685 (38%)
		PTZ00121	<828..>943	CDD:173412	28/117 (24%)
		MyTH4	1014..1171	CDD:470587
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
myo1hb	XP_073808376.1	None