Protein Alignment Myo10A and si:ch211-18i17.2

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: XP_700015.5
• Gene: si:ch211-18i17.2 / 571341
• ZFINID: ZDB-GENE-030131-5404
• Length: 761
• Species: Danio rerio
• Alignment Length: 796
• Identity: 157/796 - (19%)
• Similarity: 268/796 - (33%)
• Gaps: 244/796 - (30%)

  Fly  2510 HQQQQQQQQLEDAMEEQHMATDHQQQQ---QQQLGQQQG--------QQQRFLKQQSYLHSARKS 2563
            |.::::::..|...:::|..|...|.:   .|......|        :::|.|..|.     .|.
Zfish    23 HGEKEEEESFELRNQDEHTHTGRGQLEVTLSQPTRSANGTPCLSGVPEEKRSLITQK-----TKM 82

  Fly  2564 NAGQQPSSLTNGQVHHQEQ--MLQQQQ----QQSQSLPHH---DLDANYLQDESNGGT------- 2612
            ...:.|..:..|.:..:.|  .|:|::    ..|.||.::   |.||..|      ||
Zfish    83 TMDEDPEVVVKGWLLREVQGGWLRQRRFWFVLTSDSLDYYSGPDRDARRL------GTLVLTSLC 141

  Fly  2613 ----PPSVT-----KYSLLQFAMQHFRNDQLRDADRHHER--HQSAA------------------ 2648
                |...|     .:||..:..:|.    .|...:|:..  |.:.|
Zfish   142 SVLWPDKHTYKQTGYWSLTVYGRKHC----YRLFTKHYNEAVHWACAVQKVIDSKAPVETPTQLL 202

  Fly  2649 ------NRSYAELV----------KWQGHAIRLPLLRLP--------------NDLAPLALECFD 2683
                  |:...|:|          ::....:..|||..|              ..:...|:..|:
Zfish   203 IRDIEENKFNPEVVEHIYQHNPILRYTQSPLYAPLLPFPYGSLHHTHMASKGYTSIREEAVRLFN 267

  Fly  2684 CILRYCGDIPLDPDLTEVKCVYTVLMHCHKYLALRDEVYCQLMKQTTANRSPC-----PDSSQRA 2743
            |:.:      |:.....:..:..:|..|.....||||:||||:|||:...|..     |:...|.
Zfish   268 CLQQ------LESAREPIPLIQGILQTCLDLRPLRDELYCQLIKQTSTTSSRVQTQTNPNPQLRY 326

  Fly  2744 WRLLSILAAYFGCSDALRPYLMEHLTSAAS-------DRRRSCHGTAAVCLTNLRKTARCGGRKN 2801
            |:||:.::..|..|..:..||..||....|       :...|..|.|      |.||.   ||:.
Zfish   327 WQLLTCMSCTFLPSCGILRYLRFHLKRVQSLSVDPEVESYASFIGQA------LEKTR---GREC 382

  Fly  2802 VPSVEEVTAVSAGRSARRQI-----YRLPGGAERVVNTRCSTVVADVIAELCALLGVESEAEQQE 2861
            |||.||:    .|...|::|     |..||..:..:.:.  |...:|:.::...||::.  .:..
Zfish   383 VPSWEEI----QGLMGRQEILCTVHYPGPGCCQIPITSH--TTANEVVRKMAERLGLQD--SRNT 439

  Fly  2862 FSLYCIVQGDAFTMPLAADEYILDVTT--ELLKSGQPFYLIFCRSVWHFALKREPAPMPLYVEVL 2924
            |.|:  .|...:...:.....|.||.|  |.|.:..|.....||..:           .||..:.
Zfish   440 FGLF--EQNACWEKAIGGSTIIADVITRFENLSAKDPDSDCQCRLCF-----------KLYCLLD 491

  Fly  2925 FNQVAPDYLEGLLL-----ELPGNGVPVPEMVRDMARIAA-----LLHRAADLSHVPAMKEI--- 2976
            ...::.|.:|.|.|     |:...| .:|....|:..:||     ||...:.||..||::::
Zfish   492 TENISTDSIEYLFLYEQCHEMVVRG-QLPACEEDLLSLAALRLQYLLGDFSALSPYPALEQLFPA 555

  Fly  2977 ------KFLLPKPALG-----------------------------IREIRPAQWVGLVQSAWPQV 3006
                  ..|.|....|                             :|| ..|..:..:...|..:
Zfish   556 EVVEARALLAPVDPPGCPSFPGGLLAGTLWGHKRRQEQDQRLRARLRE-EGAVVMSTILERWKAL 619

  Fly  3007 ANLSPGQVKAQFLNVLATWPLFGSSFFAVKRIWAEEGPHVEDNHSPMWRDL---ILALNRRGVLF 3068
            ...|.....|.:|.:...|..||.:.:.|....:..|...:    .:|..:   .:.|.|:|
Zfish   620 VGYSGRDSMAAYLTIARQWSGFGCTLYEVDFYISSTGSFSQ----KLWLGVAASCVTLYRQG--- 677

  Fly  3069 LDPNTHETLQHWSFMEVIS-------TRKVRSEDGALFLDMKVGNLMQQRVIRVQTEQAHEISRL 3126
                ..|.|:.....::.|       |.::.:.|               |.:..:|.:..||.:|
Zfish   678 ----EAEALESLPITQICSYGVSDSNTFRITAGD---------------RDLLFETTKLTEIMQL 723

  Fly  3127 VRQYI--TMAQISQRD 3140
            :..|.  |..|:.:.|
Zfish   724 MNAYFSATRRQLGKDD 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838
		PTZ00121	<828..>943	CDD:173412
		MyTH4	1014..1171	CDD:470587
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939	39/117 (33%)
		FERM_B-lobe	2920..3025	CDD:271216	27/152 (18%)
		FERM_C_MyoXV	3029..3138	CDD:270022	20/120 (17%)
si:ch211-18i17.2	XP_700015.5	PH-like	86..199	CDD:473070	23/122 (19%)
		MyTH4	282..390	CDD:459939	39/120 (33%)
		FERM_F1_PLEKHH3	395..490	CDD:340727	23/111 (21%)
		B41	400..646	CDD:214604	50/264 (19%)
		PH-like	642..733	CDD:473070	19/116 (16%)