|
Fly 37 ALIKGKMRIVRFHLEPWQRGGGGSVTPSPAQSPSL--ALLSPHVLRR--QRPASLEDF------- 90
||:...:|..|:.|........|...|: ||.| ||.:|::.:. |.|:.:..:
Zfish 1877 ALLNQNLRNARYRLPDGSVLTQGFAVPT---SPDLIDALKNPNLKKASYQLPSGISSYMTSSGQV 1938
Fly 91 -------------------------------EDLPNLSAKHPALPSSRLRRL-KCRYPQVVKRLS 123
:...:|.|....||...::.| |....:..|.:.
Zfish 1939 IIGPDGRYAIVPPRQKGPGPEEHWAQNAREGQTAEDLWASEKVLPHDTVQNLIKWSMYRDEKMMD 2003
Fly 124 TLCSDVIARHPQTFALQPG----------EG-----------SLRA------RQDLGSSGVEDMT 161
.|. |....|:|| || |:|: |......|.||||
Zfish 2004 FLT-------PPPTVLRPGQTEPQWVPDREGEPRGTWYDKMYSIRSLPTVSYRVKRKGDGTEDMT 2061
Fly 162 LLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGSLPPHLF 226
.::.|.|.::|.||::|:|:.||||:.||||::||||::| :.||.::..||.|..:...|||||
Zfish 2062 QMEQLTEPAVLINLKIRFDQELIYTYIGSILVSVNPYQLF-NIYGTDMVLQYEGHAMADNPPHLF 2125
Fly 227 AIGAAAHAA---LPSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQILEAAPLL 288
||...|:.. :...|.::|||||||||||:||||::||.|: .....||:|||||.|||
Zfish 2126 AIANVAYTTMMDIKQNQCIIISGESGSGKTEATKLVLRYLTAI-----HHKRNITQQILEATPLL 2185
Fly 289 EAFGNARTARNDNSSRFGKYLEVYFKSGAIVGAKITQYLLEKSRIVTQAPGERNYHVFYELLGGL 353
|:||||:|.||||||||||::|::.:.|.|.||..:||||||||||.||..|||||:|||:|.||
Zfish 2186 ESFGNAKTVRNDNSSRFGKFVEIFLEEGVISGAITSQYLLEKSRIVFQAKDERNYHIFYEMLAGL 2250
Fly 354 -SETERSKYGLLEADKYFYLNQGATDCASGRVDWES---LQGAMQVLGVSEGEREGIVRVLAAVL 414
|.|:|:.| |.||:.|:|||||.....:|:.|.|. ||.||.:|..|..::..|.|||:::|
Zfish 2251 PSHTKRAFY-LQEAETYYYLNQGGNCGITGKDDGEDFRRLQSAMDILHFSTEDQSSIFRVLSSIL 2314
Fly 415 HLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTEARAERLHTPLGIDQ 479
|||||:|||.: ...||...|.|..||:..|.||.||.:||.:|:|.:.|||..|:::|||.::.
Zfish 2315 HLGNVFFHRVE-TEVQETAGVVSTQEIRAVADLLQISPEGLQKAITFKVTEAMREKIYTPLSVES 2378
Fly 480 ALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENSFEQLCINYANE 544
|:|||||.||.||:.|||||..|||..|.. .::|..||:|||:|||.|..|||||||||||||
Zfish 2379 AVDARDAVAKILYSLLFNWLTDRINGRVYP--RNEALSISLLDIYGFESLVFNSFEQLCINYANE 2441
Fly 545 NLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFPRATDLSF 609
.||.:|:|.:||.||.||.||::.|..|.:.||...|.|::.||.|:..:|||:|.||:|||.:|
Zfish 2442 TLQFFFSKIIFKQEQEEYIREQINWKELTFTDNQACIDLISAKPHGLLRILDDQSCFPQATDNTF 2506
Fly 610 LEKCHYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLASSRLPLVG 674
|:||||:|..:.||::|::...||.|.||||:|.|.|..|||||.|.:|.:||:|...|:...|.
Zfish 2507 LQKCHYHHGNNPLYSKPKMPLPEFTVYHYAGRVTYQVHKFLDKNFDQVRQEVLDLFMQSQNRTVS 2571
Fly 675 EL----TKQLRAQRDAGKTLPKGSNGR--FVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRC 733
.| ::.|..| ||:..| .||.:.:..||||:|..|||:||..|.||:|:||||
Zfish 2572 NLFIKHSEMLNQQ--------KGAMNRSSTVTRRYQPSTVAAKFQQSLQELLDKMERCNPFFVRC 2628
Fly 734 IKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRHLL----PSPLARG 794
||||..|.....|...|..||||.|:||||:||:.|||:|:.|..|:.||:.|| |.| :.|
Zfish 2629 IKPNNNKEPGIFDPELVATQLRYSGILDTIRIRKEGYPIRVPFHKFLNRYKALLGMKKPPP-SDG 2692
Fly 795 TPYRELCRALLEAMPRTGVEGPDYQLGATRVFLREALHRALESGRTERLRRAAVSVQRHVRGMLV 859
:.|..:|..: ..:...|||:|.:::||:|.:::.|||.|...:..||:::||:||....
Zfish 2693 ----DNCVMMLTKL--CPINKGDYQVGVSKLFLKEEVYQLLESKRDRVMHIAALTLQRYVRMFFA 2751
Fly 860 RRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQ---RLWRGRQARRRVQQLRSDHRRRQE 921
||:..:.:...|.|||..:|..|:||:.|:|...:..: ||...|:...|:..|.: ||.:|
Zfish 2752 RRKFLKFRLTMTHLQAHCKGFMARQRFLRMRINLIRHRAMIRLIVNRKRYIRINVLLA--RRAEE 2814
Fly 922 AREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHGDRHLVKVLGTVPGP--- 983
.|...:..|.:|| |:..:||. |||||..:.....|....|.| .|..|..|
Zfish 2815 ERRRLELERISRE----VVNVTQLV---IPAELGGLLQATAGGRERHSD-----CLALVQAPRIQ 2867
Fly 984 PSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPL---LTRAASRDQDFQDALAVFKLIL 1045
....:.||.|:......|:...:...|.. ..:|||| |||. .|...|||:.||.|||
Zfish 2868 TDPQLTLPLDINNHLMTKYIRTHFRELLF----GMLTAPLENSLTRL--EDDLKQDAVDVFILIL 2926
Fly 1046 RWSNDKALEGAKEKLLADYIVHKALSSRGLRDEILVQLCNQVHGLPPNSGEATRLWQLLGQCLCC 1110
|:..|..|.||:|.|..:||:.:.|::..:|||||.|:.||| ....||..|.|.|.|:..||..
Zfish 2927 RFMGDPNLNGAQENLFGNYIIQRGLATPPIRDEILAQIANQV-WRNENSRNAERGWLLMAACLSS 2990
Fly 1111 FQPSAAFSKYLMRFVDDEAPESLRPLLLRQLLRQQGGGTSSGAVGAGACRSFVPAWLEWRAWTRG 1175
|.||....|||::||.|.|....:.|...:||: ......:...|.|::.|:.|||.|..:.
Zfish 2991 FAPSEKMEKYLLKFVSDYALNGFKALCQHKLLQ----AMQKSYLVPEASRTYPPSLLEWTATRKK 3051
Fly 1176 CDMALPLTLPDEASQTVAVDSWTSCEEAAALAVSSLGVASR---GWTLVLDDGQQLTDSCGLDYV 1237
..|.|.:...|..|....|.|||:.|..|...:...||::. ||::::.:..|..:..|.|||
Zfish 3052 AHMVLQVHCFDGVSFLCPVHSWTNGEGLAGDVLQHRGVSAESRWGWSVLMKEPAQWVELEGHDYV 3116
Fly 1238 MDLIAEKELCPAFPAPRSDLLRSGAKFARTTLPDAVKRPAVPPPAPPTSSGKEDVPRERRSSREL 1302
:||:.:.||.|.||..::..:.|... |..|.|.:|
Zfish 3117 LDLVCDLELLPDFPKQKTYFIISTED---------------PSKARPNAS--------------- 3151
Fly 1303 LSRSSALNERYFEREPSPGPGQGSSTGQAKSRSKSLDDLLAGDIVPVPTDCDSQEPLHTLGLSES 1367
.|.....:.|.|..|.. .|..:..||| ::|.:||.
Zfish 3152 ---ISLFGSGFDEDEDGPLS-------------------YANRMSAVPT--------NSLPISEG 3186
Fly 1368 RLNDRYHSAERLAPVGKDTGPRYQKSQHAGRRSHAASHGSHSSKYADKAEYATRSSAMSDTSEAP 1432
..: .|:.|.|..:|..
Zfish 3187 HYS-------------LDSEPSYDATQRG------------------------------------ 3202
Fly 1433 SLASHVRRVRVPSQASDVDQFLDDLFSPVLDGSLDELSDARSLAASIRGGSYEQENEAESEIDDL 1497
:|::||.||.|||..:..:. ||..|:..::||.....:||:.
Zfish 3203 -----------------MDRYLDSLFDPVLSDAAGDF-DASVLSGRMKGGGGVGGDEAQH----- 3244
Fly 1498 DDYINDIFQPIPLVQNLEKLTSKDQLAAIIKGGGVASKPEERDEESEIEDLDDYINELFEPIPVA 1562
|:|....|.::.|.|...| |:|..
Zfish 3245 --------------------TAKVTPLAALQPGAVRVLP---------------------PMPPM 3268
Fly 1563 EGLDKLTSKEHLAVSIRGGGSTDSNGADPLLHQLMQLPGETESGPALYQQQVQRAFLQSAMAQNL 1627
.| .|::..|..:| |.....|
Zfish 3269 PG-------------------------SPIMPSLPAVP------PVPVPDQ-------------- 3288
Fly 1628 QIQQQLLAQNQALQTLLSQQA----------AAAAANNSTSPPPAPPILSSLSISPPPPQSPMRM 1682
|..:|||.| ||:|:||| |.|...:..|.||..|:.|..:..||.|.|.:
Zfish 3289 --QHAVLAQQQ--QTILNQQAVIMAQQMTMQAMAMVTSPVSSPPMSPLTSPPTSPPPTPYSTL-- 3347
Fly 1683 KATRSSLVVMESLQPPPPPPPPPMPPPLECKDPSETRHFLDPYGRAKTVRIGKWRWPPPQDEPQF 1747
||.|.|.:|| .||... ||
Zfish 3348 ----------------PPSPYPAIPP--------------SPYANI-----------PP------ 3365
Fly 1748 QTEEDFFAFKMRQHQRKTTPQAQHHQMTSNGGMMESGPGARGASATAIEWEEFEIESPTPPPMSG 1812
:|.|.....:| ||:
Zfish 3366 ------------------SPYAPMSAYSS-------------------------------PPV-- 3379
Fly 1813 QLMRSSIRLETTTTTTTSAVNNRDRDRETQDVGQPMQSVVTTKLAKKSFEIGADRPPPGSVGKLK 1877
|.|.|.::..|.:...|| |.||| .||.:
Zfish 3380 -----------TPTQTFASTPNYNASSET--------------LKKKS-------SPPNT----- 3407
Fly 1878 LSSEMRQRLEQVTAGHSVRSTVSTKSEQRAPAKLEDTRKLMLQQQLGGLFASVSGGNSGPGGVVD 1942
..||...| |..|:| |.|
Zfish 3408 ----------------QPRSNTKT---QATPSK-------------GSL---------------- 3424
Fly 1943 SHATVRTQIERMEGKLSPPPAPPSGGWPGVLLPPAPSVPAPPPPIRPPSMAPPAPPPAPQSPPTA 2007
||...|.|| :.|...|:....|..:..|..:.|||
Zfish 3425 -------------GKKQAPAAP-------IKLDSRPAKRHAPVAVTGPMRSTPAP---------- 3459
Fly 2008 RSPEPEPDYRTSSSQVVKEHVPAFIQRQERDTFGAVRQQQMISSHHLHLEDHSASSSPAVAAWEQ 2072
.::||| :.....:.::.||::
Zfish 3460 ------------GTEVVK--------------YSVSNSEHIVPSHNI------------------ 3480
Fly 2073 AERERSRSRSRSRD-REDYSESVWDRAEVEGPASGSGSEKEREKRERERERLYEIRQVERERESH 2136
:| .:.|.....:.|.::....|.|..|::...: |..|:.:.:..:
Zfish 3481 ------------KDIIKQYQTPTPEPAPLKQKRDGKGFVKKKNPHD-------EAMQILKTQMDN 3526
Fly 2137 KVYQPAPPRVIQASMDTTGGHRREDRTGGLATFRTHMAQKYEHERKRKSSASSGMREELDSMHMT 2201
|.|| |....|.....|:: || :..||| :::.....:|
Zfish 3527 ----PPPP---QRHAPTPAAVSRDE---GL--------------KPTKSS-----KKKAPEPPLT 3562
Fly 2202 TPPPVIVPAPVPPPSSTSPGLGVVSGVLMGSGSGGSTACLTYNRVPWKLRVRKEVFQPHEPIGPP 2266
.||||....||...|..:| ....|:....||..||||:.:|||||.|.:.....
Zfish 3563 LPPPVSRDLPVETESIQTP-----------LHRSGTEEHYTYTNVPWKIYLRKEVFYPKDSWNHL 3616
Fly 2267 VALDLLFAQVLGDVFGVTPCLRITPQEKSSALNMLHGHGVSVDT-LSNRNGSGAGGGGNGGQVRA 2330
:.|||:|.|::.|.| ...|:|||.:|:....::...:|:..:| :.:.:
Zfish 3617 LVLDLIFKQIVNDTF-TEACVRITKEERQKMKSLFAQYGIEPNTDVQDES--------------- 3665
Fly 2331 LVKRHLVDMARD-WPLYFARLFAVQGAPLYPDVSIMGVSHSGLYLAR------RDADYLIVVQAI 2388
||:.::..||: |.:||:|||...|: :...|.::.|||:|:.|.: ...||..|::..
Zfish 3666 -VKKTVIAAARESWEIYFSRLFPASGS-VGTGVQVLAVSHTGIKLLKTVKSSTAAPDYFRVLRPY 3728
Fly 2389 SFGEIQSAVTLPRPAALQLNLRNGKHLALHAARAAAIQSMVTTFVQEFRKSQSKASTLSSGARAA 2453
|:.:| ..||:|.|..|:.||.|.| |.|.:|:|..|:.||..|:...:|
Zfish 3729 SYLDI-LFVTIPSPNMLEFNLMNEK-LILFSAKAPQIKQMVDLFISHLKK--------------- 3776
Fly 2454 AQTLNVPLERLESRQAHAQRNEHGVDGGSRQNEQLQQSELHHHLQQQQQQQQQQQHHQQQQQQQQ 2518
:|....|:||....| :|.|: .|:....:.|
Zfish 3777 -----------DSEYVVAERNFITED----------RSLLN--------------FHKGDIIRLQ 3806
Fly 2519 LEDAMEEQHMATDHQQQQQQQLGQQQG-----------QQQRFLKQQSYLHSARKSNAGQQP--- 2569
..|.:|| ||..| :.:|......:.:.|.:..:|..|
Zfish 3807 AMDGLEE---------------GQSYGCVVKKKVIYLEELKRGTPDFGWRYGAVQGRSGAFPMEC 3856
Fly 2570 ------SSLTNGQVHHQEQMLQQQQQQSQS----------LPHHDLDANYLQDESNG-------- 2610
..........:::...:|.:.:.| ...|:||.:. ||:|
Zfish 3857 VVPVAAPDFLGLPAERRDEPRDRQGRVAASGAIALAVASTAAAHELDPSL---ESDGFGDFGDSE 3918
Fly 2611 --GTPPSVTKYSLLQFAMQHFR------NDQLRDADRHHERHQSAANRSYAELVKWQGHAIRLPL 2667
|.....::|::::||.::|| :|..||..: :...::..||:||:..:.|...|
Zfish 3919 AEGNVVLDSQYNMVEFARKYFRTSDGSKSDSFRDKSK-----KGKGSKDPAEMVKFNKNPILESL 3978
Fly 2668 LRL--PNDLAPLALECFDCILRYCGDIPLDPDLTEVKCVYTVLMHCHKYLALRDEVYCQLMKQTT 2730
:.. || :..:|.|.|..|:::.||.||... :|...|.|.|....:|..::||.|||::||.|
Zfish 3979 IDFTDPN-MNRVASEIFLAIMKFMGDHPLRGQ-SEQFVVCTFLKLTGEYGLMKDEAYCQVLKQIT 4041
Fly 2731 ANRSPCPDSSQRAWRLLSILAAYFGCSDALRPYLMEHLTSAASDRRRSCHGTAAVCLTNLRKTAR 2795
||.|..|||.|:.||||.||.|::.||:.|:|:|::.|...........||.|..|..|||||.:
Zfish 4042 ANTSSKPDSCQKGWRLLYILTAFYRCSEVLKPFLLKFLRDVCRSPEVHFHGIAKTCEQNLRKTFQ 4106
Fly 2796 CGGRKNVPSVEEVTAVSAGRSARRQIYRLPGGAERVVNTRCSTVVADVIAELCALLGVESEAEQQ 2860
.|||...||..|:.|:.||||::||::..|||.||.:..:..:|..|||.|||..:.::......
Zfish 4107 FGGRSVYPSSMELKAIMAGRSSKRQLFLFPGGIERHLKIKTCSVALDVIEELCYEMALQRLEAMD 4171
Fly 2861 EFSLYCIVQGDAFTMPLAADEYILDVTTELLKSGQPFYLIFCRSVWHFALKREPAPMPLYVEVLF 2925
|::::.:........||...|||||:.||..:....:...|.|.:|...||.: ..|.|.:.:
Zfish 4172 EYTVFIVTNRGQNVRPLNKREYILDIATEAEQIDANYSFWFRRVIWAHPLKFD---NELCVTMHY 4233
Fly 2926 NQVAPDYLEGLLLELPGNGVPVPEMVRDMARIAALLHRAADLSHVPAMKEIKFLLPKPALGIREI 2990
|||.||||:|||..:| .|....:.....|::|||.|||.|..:.|.:.|:...:|....| |:|
Zfish 4234 NQVLPDYLKGLLNIVP-QGKISEQQFNQFAKLAALQHRAKDSLYTPTIHELMEYIPVEIFG-RQI 4296
Fly 2991 RPAQWVGLVQSAWPQVANLSPGQVKAQFLNVLATWPLFGSSFFAVKRIWAEEGPHVEDNHSPMWR 3055
|.||:.||......|.:|:|.|.::|||.::..:|:||||||.:: ..:::.:..
Zfish 4297 -PQQWMQLVAQHVHAVQSLNPHQARSQFLGLVCAFPMFGSSFFYIQ----------SSSNNTISA 4350
Fly 3056 DLILALNRRGVLFLDPNTHETLQHWSFMEVISTRKVRSEDGAL--FLDMKVGNLMQQRVIRVQTE 3118
..|||:|:.|:.||..:|||........:|.|....|...|:. ::|:.:|:|...||.::|.|
Zfish 4351 PCILAVNQNGLHFLHKDTHEVQVKVQLKQVQSAHTQRPSAGSSYPYVDVLIGDLTNHRVTQLQLE 4415
Fly 3119 QAHEISRLVRQYITMAQISQRDKR 3142
|..|:.|::..:|. ..:|.|:||
Zfish 4416 QGLELCRVIAMHIE-NMLSVREKR 4438
| 
