Protein Alignment Myo10A and myo1ca

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: NP_001418059.2
• Gene: myo1ca / 567536
• ZFINID: ZDB-GENE-070705-190
• Length: 1045
• Species: Danio rerio
• Alignment Length: 1017
• Identity: 323/1017 - (31%)
• Similarity: 509/1017 - (50%)
• Gaps: 165/1017 - (16%)

  Fly   143 EGSLRARQDLGSSGVEDMTLLDDLH-EASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYG 206
            |.:|.||..:   ||:|..||::.: ||:.:.|||.||.:|||||:.||:|::|||||.. :.|.
Zfish    19 ESALSARDRV---GVQDFLLLENHNSEAAFIENLRRRYREGLIYTYIGSVLVSVNPYKEL-EIYS 79

  Fly   207 LEVAKQYAGRPLGSLPPHLFAIGAAAHAALPS---PQVVVISGESGSGKTESTKLVMQYLAAVVP 268
            .:..:::.|.....:.||:||:...::.||.:   .|.::||||||:||||::|.::||...:.|
Zfish    80 KQNMERHRGVNFYEISPHIFALADNSYRALRTERRDQCILISGESGAGKTEASKKILQYYTHICP 144

  Fly   269 GGGSASAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYFK-SGAIVGAKITQYLLEKSR 332
            ...: :..|.|::|::.|:|||||||:|.|||||||||||:::.|. .||.:|..|..|||||||
Zfish   145 TRNN-THTIRERLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDIQFDYKGAPIGGHILNYLLEKSR 208

  Fly   333 IVTQAPGERNYHVFYELLGGLSETERSKYGLLEADK-----YFYLNQGATDC-----ASGRVDWE 387
            :..|..||||:|:||:||.|..:....:.||   ||     |.||.:|  :|     .|.:..|:
Zfish   209 VAHQNHGERNFHIFYQLLEGGEDLLLKRLGL---DKTNPQHYHYLIKG--NCPRVSSISDKNGWK 268

  Fly   388 SLQGAMQVLGVSEGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEG-VEVGSDAEIKWAAHLLHIS 451
            .::.|:.::|..:.|.:.::.::|:||||||.     |....:|| ..:.::|::::.:.||.:.
Zfish   269 VVRNALTIIGFEDEEIQALMEIVASVLHLGNT-----QFGEDEEGETHITTEAQLQFLSQLLGVD 328

  Fly   452 ADGLHRALTSRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRIN-SIVQKGGTHDA 515
            ...|..|||.:...|:.|.:.:||.::|||.|||:||||:|...|.|||.::| |:..|...:.:
Zfish   329 GSVLKAALTHKKIVAKGEEMISPLSLEQALSARDSFAKAIYGRAFTWLVQKLNQSLAFKDEIYYS 393

  Fly   516 HR----ISILDIFGFEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDD 576
            .:    |.:|||:|||....|||||.||||.||.||..|.:...|.||.||..|.:.|..:.:.:
Zfish   394 SKCSSVIGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGVVWERVEYFN 458

  Fly   577 NLPVIHLLAKKPVGICHLLDDES-NFPRATDLSFLEK--------CHY-NHALSELYARPRIGAQ 631
            |..:..|:.:|..||..:||:|. ....|:|::||||        .|: .|.::....|..||.:
Zfish   459 NKIICDLVEEKHKGIIAILDEECLRRGDASDITFLEKLEDTLGGHAHFITHKMANGKIRKAIGRE 523

  Fly   632 EFGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLASSRLPLVGEL--TKQLRAQRDAGKTLPKGS 694
            ||.:.||||:|.|.|:||||||.|.|...:.|:|..|...:|.:.  ..:|..||
Zfish   524 EFRLVHYAGEVNYNVNGFLDKNNDLLYRHLKEVLCQSTNHIVSQCFHADELMDQR---------- 578

  Fly   695 NGRFVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGM 759
                     |..|.|.:|..||.:|:..:....|.:|||||||..|...|.|...|..|::|||:
Zfish   579 ---------RPETAATQFKLSLAKLMDILMSKEPSYVRCIKPNDGKQPGRFDEVLVRHQVKYLGL 634

  Fly   760 LDTIQIRQRGYPVRLRFQHFVERYRHLLPS--PLARGTPYRELCRALLEAMPRTGVEGPDYQLGA 822
            ::.:::|:.|:..|..::.|:|||:.|.|.  |...|    .|...:...:.....:..:::||.
Zfish   635 MENLRVRRAGFAYRRSYEAFLERYKSLCPDTWPNWHG----NLPEGVATLVKHLNYKPEEFKLGR 695

  Fly   823 TRVFLREALHRALESGRTERLRRAAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYE 887
            :::|:|        ..||..:...|:.              |::|..|..||..|||.|.:..|.
Zfish   696 SKIFIR--------FPRTLFITEDALE--------------AQKQTIAVTLQKSWRGYRERANYH 738

  Fly   888 RLRKGALTAQRLWRGRQARRRVQQLRSDHRRRQEAREAAQRAR----------EAR-EAKQAVLE 941
            |:|...:..|..|||.:.||:.:     ||     |:||...|          |.| ...:..|:
Zfish   739 RIRHAVIVIQSWWRGVKGRRKAK-----HR-----RQAADTIRNFIKGFILRNEPRCPDNEYFLD 793

  Fly   942 RSQLSYL-----DIPAELAFIYSKLQGWSPPHGDRHLVKVLGTVPGPPSSAVQLPEDLGQFSFGK 1001
            ..:.|:|     ::|..:..     :.|                |.||.|..:..|.:.:.....
Zfish   794 HVRFSFLMKVKRNLPKSVLD-----KSW----------------PKPPPSLTEASEHIHRICIRN 837

  Fly  1002 FSSVYCNGLRLQPR-REPITAPLLTRAASRDQDFQDALAVFKLILRWSNDKALEGAKEKLLADYI 1065
            ..:.||.  |:||. |:.:...::.....:.|....:.:|.||.:           ..:|.|:.|
Zfish   838 LVNDYCR--RIQPEWRKQLEQKVVASGIFKGQKDGYSRSVPKLFV-----------ATRLEAEEI 889

  Fly  1066 VHKALSSRGLRDEILVQLC---NQVHGLPPNSGEATRLWQLL 1104
            ..|.|.:.|..:::...:.   ...||..|      |:.|||
Zfish   890 NLKVLQTLGSDNKVKYGIAVTKYDRHGFRP------RVRQLL 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	250/692 (36%)
		PTZ00121	<828..>943	CDD:173412	31/125 (25%)
		MyTH4	1014..1171	CDD:470587	19/95 (20%)
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
myo1ca	NP_001418059.2	None