|
Fly 145 SLRARQDLGSSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEV 209
:|:........||:||..|.||.||.||.||.||:.:|:|||:.||:|:|:|||:|.| .|..:.
Zfish 51 ALKPMHPTSVEGVDDMICLGDLSEAGLLRNLFLRHKQGIIYTYIGSVLVAMNPYEMLP-IYTADQ 114
Fly 210 AKQYAGRPLGSLPPHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGG 271
.:||.||.||.||||:|||..:.:..: ...|..:||||||:||||||||::|:|||| .
Zfish 115 VQQYHGRKLGELPPHIFAIADSCYFNMRRNKRNQCCIISGESGAGKTESTKLILQFLAAV----S 175
Fly 272 SASAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQYLLEKSRIVT 335
...:.|.:||::|.|:|||||||:|.|||||||||||:|::| |:|.|.||.:.||||||||:..
Zfish 176 GQHSWIEQQIIQANPILEAFGNAKTIRNDNSSRFGKYVEIFFNKAGVIEGAHMEQYLLEKSRVCH 240
Fly 336 QAPGERNYHVFYELLGGLSETERSKYGLLEADKYFYLNQGATDC--ASGRVD---WESLQGAMQV 395
||..|||||:||.:|.|:....:....|.:|.::.||.:| || ..||.| :..::.|::|
Zfish 241 QALQERNYHIFYCMLAGMQSDHKKTLSLGDASEFNYLTEG--DCLTCDGRDDADEFARIRSALKV 303
Fly 396 LGVSEGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALT 460
|..::.:...|.::|||:||:||:.| :..:.:..:..:|.|.:.....|.||.:....|.::||
Zfish 304 LTFTDRDCWEIFKLLAAILHMGNIDF-QSTIMNNMDSCDVLSSSHFSVIAKLLEVDDAALDKSLT 367
Fly 461 SRTTEARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGT----HDAHRISIL 521
.|:.....|.:..||..:||.|.|||||||||..||.|:.::|||.:.|..| :....|.:|
Zfish 368 HRSFMTNREMVTKPLSSEQATDIRDAFAKALYGRLFVWMFTKINSAIHKPQTDEPSYTRQSIGLL 432
Fly 522 DIFGFEDLAENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAK 586
||||||:..:|||||||||:|||:||.:|.:|||||||.||.:|.:.|..:|::||...:.|||.
Zfish 433 DIFGFENFPQNSFEQLCINFANEHLQQFFVRHVFKLEQDEYTKEGISWKRIAFNDNQKTLDLLAL 497
Fly 587 KPVGICHLLDDESNFPRATDLSFLEKCHYNHALSELYARPRIGAQ-EFGVTHYAGQVWYCVDGFL 650
||:.|..|:|:||:||:.||.:.|.|....|..::||...|...: .|||.|:||.|:|..:|||
Zfish 498 KPLNILALIDEESHFPKGTDATMLNKLSQEHKGNKLYISSRGDHRIHFGVQHFAGLVYYDCEGFL 562
Fly 651 DKNRDALRGDVLELLASSRLPLVGELTKQ---LRAQRDAGK-----TLPKGSNGRFVTMKPRTPT 707
:||||.:..|:|||:..|...|:.::.:: :.:.:::.| ..||.|..:....:.:..|
Zfish 563 EKNRDTVSMDILELIRKSSNKLLKQIFEKEINVNSVKNSNKMNKAVMTPKNSLRQVNESRRQIST 627
Fly 708 VAARFADSLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPV 772
::.:|..||..|::::..|.|:|:||.|||.:|..:..:....:|||||.|||:||:||:.|||:
Zfish 628 LSGQFRQSLDSLMKALSLCQPFFIRCFKPNDKKLPMVFNRELCMQQLRYSGMLETIRIRKLGYPI 692
Fly 773 RLRFQHFVERYRHLLPS--------PLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLRE 829
|..|:.|:.|||.||.| |.|:.. ..:||.|:: :..|:::|.|:||||.
Zfish 693 RHTFKDFLHRYRALLKSIDCDPNTEPAAKCC--AAICRTLIK-------DEEDWKIGKTKVFLRG 748
Fly 830 ALHRALESGRTERLRRAAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGAL 894
.....||..|.:.|.|.|:.:||.:.....|:....::.||..||..|||.:.::.:..:::|
Zfish 749 HHDTYLELERAQELYRKALIIQRVMLAHKDRKNFINKRKAALVLQKNWRGYKEKRDFCTVKQG-- 811
Fly 895 TAQRLWRGRQARRRVQQLRSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYS 959
..|| ||:.|.::|..::.||:.| |::.::|
Zfish 812 -FARL----QAKVRSRKLHEEYMRRRAA---------------AIVLQTQ--------------- 841
Fly 960 KLQGWSPPHGDRHLVKVLGTVPGPPSSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPLL 1024
|..||
Zfish 842 ------------------------------------------------------------TRGLL 846
Fly 1025 TRAASRDQDFQDALAVFKLILRWSNDKALEGAKEKLLADYIVHKALSSRGLRDEILVQLCNQVHG 1089
.| |.|:..||.: ||:|
Zfish 847 AR------------------------KELKSKKEAV------------------ILLQ------- 862
Fly 1090 LPPNSGEATRLWQLLGQCLCCFQPSAAFSKYLMRFVDDEAPESLRPLLLRQLLRQQGGGTSSGAV 1154
Zfish 863 ----------------------------------------------------------------- 862
Fly 1155 GAGACRSFVPAWLEWRAWTRGCDMALPLTLPDEASQTVAVDSWTSCEEAAALAVSSLGVASRGWT 1219
|.|||
Zfish 863 ----------------AQTRG-------------------------------------------- 867
Fly 1220 LVLDDGQQLTDSCGLDYVMDLIAEKELCPAFPAPRSDLLRSGAKFARTTLPDAVKRPAVPPPAPP 1284
|:|.|.|
Zfish 868 --------------------LLARKSL-------------------------------------- 874
Fly 1285 TSSGKEDVPRERRSSRELLSRSSALNERYFEREPSPGPGQGSSTGQAKSRSKSLDDLLAGDIVPV 1349
:|..|.|.|: ::.|...:|.|.::
Zfish 875 ----------KRMKSEEFLT----------------------------AQEKQAQELAALEL--- 898
Fly 1350 PTDCDSQEPLHTLGLSESRLNDRYHSAERLAPVGKDTGPRYQKSQHAGRRSHAASHGSHSSKYAD 1414
:.||.:.....|..|
Zfish 899 ----------------QQRLEELLRKNEETA---------------------------------- 913
Fly 1415 KAEYATRSSAMSDTSEAPSLASHVRRVRVPSQASDVDQFLDDLFSPVLDGSLDELSDARSLAASI 1479
.||.::.::.::::|: .|..:|
Zfish 914 -----------------------------KSQNNEDEEMVENIFN--------------FLPTAI 935
Fly 1480 RGGSYEQENEAESEIDDLDDYINDIFQPIPLVQNLEKLTSKDQLAAIIKGGGVASKPEE------ 1538
.| ||..|....:: |:..| .||...:.:.:.:....|.|.||.
Zfish 936 AG----QEGPAPEGFEE--------FEAEP-----AKLEEVELIESPVVETKVMSIPESSEDHQV 983
Fly 1539 RDEESEIEDLDDYINELFEPIPVAEGLDKLTSKEHLAVSIRGGGSTDS----NGADPLLHQ---- 1595
::||.|.|| |::....|..: |.. |.||.| ....|||:.
Zfish 984 KEEEEEEED-DEFSFSKFASL-------------HFQ-----GASTHSYIQQRLRQPLLYHEDEG 1029
Fly 1596 -----------LMQLPGETESGPALYQQQVQRAFLQSAMAQNLQIQQQLLAQNQA---------- 1639
:::..|:. |...|::| ||||..: |:.|.|.||
Zfish 1030 DTLACLTVWWIILRFMGDL---PEPKQERV------SAMADPI---QRNLGQRQARRLSNLVGLD 1082
Fly 1640 ---LQTLLSQQAAAAAANNSTSPPPAPPILSSLSISPPPPQSPMRMKATRSSLVVMESLQPPPPP 1701
|:..:.||.......:|..|...| ...|:| :|:|.:...||:....|....
Zfish 1083 QKFLRKKMKQQKGGGKRKHSAIPEEEP---------EEEPKS--QMEAVQEEQVVLFGEGPTFDR 1136
Fly 1702 PPPPMPPPLECKDPSETRHFLDPYGRAKTVRIGKWRWPPPQDEPQFQTEEDFFAFKMRQHQRKTT 1766
|..|: |..|.:..|...: |..:||...|..:
Zfish 1137 PMTPL----------EKLHIIVGYAIVR---------PDIRDEIYCQICK--------------- 1167
Fly 1767 PQAQHHQMTSNGGMMESGPGARGASATAIEWEEFEIESPTPPPMSGQLMRSSIRLETTTTTTTSA 1831
|:|.|
Zfish 1168 ------QLTGN------------------------------------------------------ 1172
Fly 1832 VNNRDRDRETQDVGQPMQSVV------TTKLAK--KSFEIGADRPPPGSVGKLKLSSEMRQRLEQ 1888
::|::.:.|..:.|:. |.:|.| :||. ..|..:.|:...:||
Zfish 1173 -----KNRKSVNRGWILLSICLGIFSPTERLTKYLQSFI---------RCGPSEYSAYCAERL-- 1221
Fly 1889 VTAGHSVRSTVSTKSEQRAPAKLEDTRKLMLQQQLGGLFASVSGGNSGPGGVVDSHATVRTQIER 1953
|.|::.......|..:| || |..|..|.||. :..
Zfish 1222 -------RRTLANGERNEPPCWVE------LQ----------SVENKNPIGVA---------VGL 1254
Fly 1954 MEGKLSPPPAPPSGGWPGVLLPPAPSVPAPPPPIRPPSMAPPAPPPAPQSPPTARSPEPEPDYRT 2018
|:|: .:.| |..|.....:..|
Zfish 1255 MDGR-------------NISL-------------------------------TVDSASTSAEVCT 1275
Fly 2019 SSSQVVKEHVPAFIQRQERDTFGAVRQQQMISSHHLHLEDHSASSSPAVAAWEQAERERSRSRSR 2083
:.|| ....:|:||......|.
Zfish 1276 AISQ----------NTNLQDSFGFSLYAAMY---------------------------------- 1296
Fly 2084 SRDREDYSESVWDRAEVEGPASGSGSEKEREKRERERERLYEIRQVERERESHKVYQPAPPRVIQ 2148
|.:| :.||||: .::.
Zfish 1297 --------EKMW--------SLGSGSQ----------------------------------HILD 1311
Fly 2149 ASMDTTGGHRREDRTGGLATFRTHMAQKYEHERKRKSSASSGMREELDSMHMTTPPPVIVPAPVP 2213
| ....|.|.||:. |||
Zfish 1312 A------------------------VSMCEQEEKRQG------REE------------------- 1327
Fly 2214 PPSSTSPGLGVVSGVLMGSGSGGSTACLTYNRVPWKLRVRKEVFQP-HEPIGPPVALDLLFAQVL 2277
...||:|..|||:|.| |:.....::.:|::.|::
Zfish 1328 ------------------------------QHAPWRLYFRKEIFTPWHDCSSDQISTELIYRQII 1362
Fly 2278 -----GDVFG------------------------------VTPCLRITPQEKSS------ALNML 2301
|:... |..|:.:|..|..| .:|..
Zfish 1363 HGLKNGEYLSDKEDDYVQLAAKHYYVQHGSESSLEIAQKIVRDCMNMTIIENKSLVKLVQLVNSA 1427
Fly 2302 HGHGVSVDTLSNRNGSGAGGGGNGGQVRALVKRHLVDMARD-WPLYFARLFAVQ--GAPLYP-DV 2362
|..|..::| |....: ||...|:.|:. ||::|::|:..| ..|..| |.
Zfish 1428 HTQGPYINT-------------NTPVYK--VKSETVEYAQQKWPIHFSKLYEAQVISGPSVPQDQ 1477
Fly 2363 SIMGVSHSGLYLA-RRDADYLIV-------VQAISFGEIQSAVTLPRPAAL-QLNLRNGKHLALH 2418
.::.|:..|::.. ..:.::|.: ::.:|.......|.|..|..: :|.:..||.|.
Zfish 1478 FVVVVNWKGVFFQDETEGEFLQLSYPEVSRIEIVSEDRSGGLVCLTTPKGMYELKIVKGKELV-- 1540
Fly 2419 AARAAAIQSMVTTFVQEFRKSQSKASTLSSGARAAAQTLNVPLERLESRQAHA----QRNEHGVD 2479
.:|..|:...::....|..:...:|....|| |..|:... :..|:.::
Zfish 1541 --------ELVNMFISGLKERSMYAVAIQDLSRQEDPTL------LSYRRGDVLYIIKDGEYSLE 1591
Fly 2480 GG--SRQNEQLQQS---ELHHHLQQQQQQQQQQQHHQQQQQQQQLEDAMEEQHMATDHQQQQQQQ 2539
.| ..:||:..|: .| ||::...|.|...::....
Zfish 1592 EGWIKARNERTSQTGAVSL---------------------------DAIQILPMLTRPTEETLNL 1629
Fly 2540 LGQQQGQQQRFLKQQSYLHSARKSNAGQQPSSLTNGQVHHQEQMLQQQQQQSQSLPHHDLDANYL 2604
|. |..||:.:. .| :|.|:::.|.....|
Zfish 1630 LN---------------LSPARRKSV--MP-------------VLPQKEELSTERVAH------- 1657
Fly 2605 QDESNGGTPPSVTKYSLLQFAMQHFRNDQLRDADRHHERHQSAANRSYAELVKWQGHAIRLPLLR 2669
..::.|..|..||......|.:....:.:|. ....::.||:|
Zfish 1658 -------------------MTLKEFSFDYFRDPVNEGRRGKGGKEKLWAN----SKEPLKQPLIR 1699
Fly 2670 L---PNDLAPLALECFDCILRYCGDIPLDPDLTEVKCVYTVLMHCHKYLALRDEVYCQLMKQTTA 2731
. .::|..||.:.|..||:|.||.|:....|.:.....:......::.||||:|||:|||.|.
Zfish 1700 NLQGNSELCHLASDSFTAILKYMGDYPVKHVRTPIDLTNQIFGPATAHVELRDEIYCQIMKQMTN 1764
Fly 2732 NRSPCPDSSQRAWRLLSILAAYFGCSDALRPYLMEHLTSAASDRRRSCHGTAAVCLTNLRKTARC 2796
||:.. |.:|.|:||.:....|..|..|..:....|.| |.....|:.||..::.....
Zfish 1765 NRNGL--SMERGWQLLWLCCGLFPPSQLLLRHAQRFLES------RPREPLASACLQRMQAMLSI 1821
Fly 2797 GGRKNVPSVEEVTAVSAGRSARRQIY---RLPGGAERVVNTRCSTVVADVIAELCALLGVESEAE 2858
.|||..|...||.|: ::...||: ..|.....:.....:|.:.|:...:...|.:.|
Zfish 1822 EGRKLPPHQVEVDAI---QNNSTQIFHKVHFPNDTSEIFEVTTTTRIKDLCRNIAKDLRLSS--- 1880
Fly 2859 QQEFSLYCIVQGDAFTMPLAADEYILD---VTTELLKSGQ----------PFYLIFCRSVWHFAL 2910
.:.:||: |:.......:.::||..| ..|::.|.|: |:.::|.|.:|...:
Zfish 1881 PEGYSLF--VKTSTKVESMNSEEYFFDNLRQLTDVTKKGKKVREATPTIVPYLVLFMRKLWFNVI 1943
Fly 2911 KREPAPMPLYVEVLFNQVAPDYLEGLLLELPGNGVPVPEMVRDMARIAALLHRAADLSHVPAMKE 2975
..:.....|... |.|..|.||.|. :.| ...||..:..||.| :.|.|.|.
Zfish 1944 PGKDITADLMFH--FPQELPKYLRGY------HSV----SKEDMIALGGLLFR----TRVDADKS 1992
Fly 2976 IKFLLPKPALGIREIRPA---------QWVGLVQSAWPQVANLSPGQVKAQFLNVLATWPLFGSS 3031
...::|:. ::|:.|| .|...:.:::.:.|.:|..:.|.|||..::.||.||.:
Zfish 1993 QFVMIPRM---LKELVPADQQKIMTAEDWKKHIINSYNKQAGMSVDEAKLQFLKTVSPWPTFGCA 2054
Fly 3032 FFAVKRIWAEEGPHVEDNHSPMWRDLILALNRRGVLFLDPNTHETLQHWSFMEVISTRKVRSEDG 3096
||.||:...:..|.| ::::::::|:..::..|.|.|....|.::.|. ..|
Zfish 2055 FFEVKQTSEKNYPSV----------IMISISKQGISLINSKTKEVLAAHLFSKITSW-----SSG 2104
Fly 3097 ALFLDMKVGNLMQQRVIRVQTEQAHEISRLVRQY 3130
:.:..|.:|||:|...:..:|.|.::||.|:..|
Zfish 2105 STYFHMTIGNLVQGNTLLCETSQGYKISDLLSSY 2138
| 
