|
Fly 147 RARQDLGSSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAK 211
||.:| ||||||.|::|||.::|.||:.|:::.||||:.||||::||||||| :.||.::..
Zfish 1828 RAEED----GVEDMTQLEELHEGAVLLNLKKRFERNLIYTYIGSILVSVNPYKMF-NIYGTDMVL 1887
Fly 212 QYAGRPLGSLPPHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSA 273
|:.|..||..|||||||..|::..: ...|.::|||||||||||:||||::||||: ..
Zfish 1888 QHKGHALGENPPHLFAIANASYTKMMDAKENQCIIISGESGSGKTETTKLVLRYLAAI-----HH 1947
Fly 274 SAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYFKSGAIVGAKITQYLLEKSRIVTQAP 338
...||:|||||.||||:||||:|.|||||||||||:|::.:.|.|.||..:||||||||||.||.
Zfish 1948 KQNITQQILEATPLLESFGNAKTVRNDNSSRFGKYMEIFMEEGVISGAITSQYLLEKSRIVFQAK 2012
Fly 339 GERNYHVFYELLGGLSETERSKYGLLEADKYFYLNQGATDCA----SGRVDWESLQGAMQVLGVS 399
.|||||:|||:|.||...::..:.|.:|:.|:|||||. ||. |...|:..|..||::|..|
Zfish 2013 DERNYHIFYEMLAGLPSQQKQSFYLQDAETYYYLNQGG-DCVIVGKSDGEDFRRLLSAMEILHFS 2076
Fly 400 EGEREGIVRVLAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTT 464
..::.||.|||:::||||||:|.|.: ...||...|.|..||:..|.||.||.:||.:::|.:.|
Zfish 2077 AEDQSGIFRVLSSILHLGNVFFERYE-TESQEVASVVSAQEIRVVAELLQISPEGLQKSITFKVT 2140
Fly 465 EARAERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDL 529
|...|:::|||.::.|:|||||.||.||:.||:||..|||..|.. .::|..||||||:|||||
Zfish 2141 ETMREKIYTPLTVESAIDARDAVAKILYSLLFSWLTDRINKQVYP--RNEALSISILDIYGFEDL 2203
Fly 530 AENSFEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHL 594
..|||||||||||||.||.:||:.:||.||.||.||::.|..:.:.||...|.|:|.||.||..:
Zfish 2204 TFNSFEQLCINYANEYLQFFFNRVIFKEEQDEYNREQIIWEEVPFSDNQACIDLIAAKPHGILRI 2268
Fly 595 LDDESNFPRATDLSFLEKCHYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRG 659
|||:|.||:|||.:||:||||:|..:.||::|::...||.:.||||:|.|.|..|||||.|.:|.
Zfish 2269 LDDQSGFPQATDHTFLQKCHYHHGNNPLYSKPKMPLPEFTIKHYAGKVSYQVHKFLDKNYDQVRQ 2333
Fly 660 DVLELLASSRLPLV-------GELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQ 717
|||:|...|:..:| .|...|.|:|.....| ||.:.:..||||:|..||.
Zfish 2334 DVLDLFIQSKNKMVAYLFMNYAEALNQQRSQIGKNST---------VTRRHQASTVAAKFQQSLL 2389
Fly 718 QLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVER 782
:|::.|.|.:|:|||||||||.|.....||..|..||.|.|:|:|::||:.|||:|:.|..|:.|
Zfish 2390 ELIEKMERANPYFVRCIKPNQNKEPAVFDMELVSAQLCYSGILETVRIRREGYPIRMPFDVFLFR 2454
Fly 783 YRHLL----PSPLARGTPYRELCRALLEAM--PRTGVEGPDYQLGATRVFLREALHRALESGRTE 841
|:.|| |.| |.| |.|..:|..: .|.|. :|:|.|::|::|.::..|||.| :
Zfish 2455 YKSLLGLKQPPP-ANG----ENCVIMLRKLCPVRPGA----FQVGVTKLFMKEEIYFLLESKR-D 2509
Fly 842 RLRR-AAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQA 905
|:|. ||:::||:.|...||::....:....||||..||...::||.::|...:..:.|......
Zfish 2510 RVRHVAALTLQRYTRMFFVRKRYTAFRMKIIRLQAHCRGFLTRKRYVKMRVSLVKFRSLVHMYVD 2574
Fly 906 RRRVQQLRSDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDIPAELAFIYSKLQGWSPPHGD 970
|:|..:||.:.||:.|.. ||..|...:|:.|: .:::|.|||||..:.....|....|.|
Zfish 2575 RKRYIRLRYEARRKAEEE---QRRIEMELSKREVV---NVTHLVIPAELGALLQAAAGGRELHSD 2633
Fly 971 RHLVKVLGTVPGPP---SSAVQLPEDLGQFSFGKFSSVYCNGLRLQPRREPITAPLLTRAASRDQ 1032
.|..|..|. .:.:.||.|:..::..|...::.. :|:...:||||.|.....|.
Zfish 2634 -----CLALVQAPTVQVETQLTLPLDINNYTISKLVQIHFK----EPKFGMLTAPLKTPLTHVDD 2689
Fly 1033 DF-QDALAVFKLILRWSNDKALEGAKEKLLADYIVHKALSSRGLRDEILVQLCNQVHGLPPNSGE 1096
|. .:||.||.:|||:..|..|.||:|.|..:||:.|.|::..||||||.|:.||| ...||...
Zfish 2690 DLTHEALDVFVMILRFMGDPHLNGAQENLFGNYIIQKGLTNLNLRDEILCQIANQV-WRNPNPDN 2753
Fly 1097 ATRLWQLLGQCLCCFQPSAAFSKYLMRFVDDEAPESLRPLLLRQLLRQQGGGTSSGAVGAGACRS 1161
:.|.|.||..||..|.|||...|||::||.|.|....:.:...:|:: .......|....|:
Zfish 2754 SERGWLLLLACLSAFAPSAKVEKYLLKFVSDHAYNEFKAVGQHKLIQ----AMQKSLYGPETART 2814
Fly 1162 FVPAWLEWRAWTRGCDMALPLTLPDEASQTVAVDSWTSCEEAAALAVSSLGV--ASRGWTLVLDD 1224
:..:.|||.|..:..:|.|.:...|..|....|.||||.||.|...:...|| |.:|.::::.:
Zfish 2815 YPLSLLEWTANRKKANMVLQVHCFDGTSFLCPVHSWTSGEELAGDILQHRGVTEAWKGCSVIMKE 2879
Fly 1225 GQQLTDSCGLDYVMDLIAEKELCPAFPAPRSDLLRSGAKFARTTLPDAVKRPAVPPPAPPTSSGK 1289
..|..:..|.||||||||:.||...||..:|..:.|.....||
Zfish 2880 HGQWAELAGHDYVMDLIADMELMRNFPKQKSYFIISAESPTRT---------------------- 2922
Fly 1290 EDVPRERRSSRELLSRSSALNERYFEREPSPGP---GQGSSTGQAKSRSKSLDDLLAGDIVPVPT 1351
.|:.|. |.| ..:
Zfish 2923 ---------------------------RPNAGLALFGSG-----------------------FDS 2937
Fly 1352 DCDSQEPLHTLGLSESRLNDRYHSAERLAPVGKDTGPRYQKSQHAGRRSHAASHGSHSSKYADKA 1416
|.|| :|.|.::.| ||...|..
Zfish 2938 DDDS-----SLLLPQTML---------------------------------------SSSLPDSD 2958
Fly 1417 EYATRSSAMSDTSEAPSLASHVRRVRVPSQASDVDQFLDDLFSPVLDGSLDELSDARSLAASIRG 1481
.| .|.|.||.||||: ...:|::||.||.|||.....:...:.|:::.::|
Zfish 2959 GY--YSHAESDFSEAPT-------------QKGMDRYLDSLFDPVLSDGNGDFEKSSSMSSRMKG 3008
Fly 1482 -GSYEQENEAESEIDDLDDYINDIFQPIPLVQNLEKLTSKDQLAAIIKGGGVASKPEERDEESEI 1545
|....|| |.:...|..|
Zfish 3009 AGGIGGEN-----------------------------------------GDLEKPPSGR------ 3026
Fly 1546 EDLDDYINELFEPIPVAEGLDKLTSKEHLAVSIRGGGSTDSNGADPLLHQLMQLPGETESGPALY 1610
|...||.. ||.|:| .:.|.|...|
Zfish 3027 --------------PYPPGLQP--------------------GAVPVL----PVMGGTMMPP--- 3050
Fly 1611 QQQVQRAFLQSAMAQNLQIQQQLLAQNQALQTLLSQQAAAAAANNSTSPPPAPPILSSLSISPPP 1675
....|:.::...||:||. |..||: |..
Zfish 3051 ------------------------IPMPAMPSVPHAQASAAV-------PSVPPM-------PAM 3077
Fly 1676 PQSPMRMKATRSSLVVMESLQPPPPPPPPPMPPPLECKDPSETRHFLDPYGRAKTVRIGKWRWPP 1740
|..| .|.::.|.|..|..|..|.:...||:
Zfish 3078 PSMP-----------AMPAMLPLPALPNVPPMPDMSGVDPA------------------------ 3107
Fly 1741 PQDEPQFQTEEDFFAFKMRQHQRKTTPQ-----AQHHQMTSNGGMMESGPGARGASATAIEWEEF 1800
.:.|||:....| || ||| ..|.|::.:.:
Zfish 3108 ----------------VLAQHQQAIINQQAIILAQ--QMT--------------MQAMALQQQMY 3140
Fly 1801 -EIESPTPPPMSGQLMRSSIRLETTTTTTTSAVNNRDRDRETQDVG----QPMQSVVTTKLAKKS 1860
.:..| ..:|:.::...:.:.| .||:| :|.......|.:::.
Zfish 3141 NSVHHP-----HSELLPAARSSQYSPT--------------KQDIGPVSYKPAPVSPPQKSSQRH 3186
Fly 1861 FEIGADRPPPGSVGKLKLSSEMRQRLEQVTAGHSVRSTVSTKSEQRAPAKLEDTRKLMLQQQLGG 1925
:......||||.|.:..:|: .|.:...|:::..: |..|..|.|
Zfish 3187 YSPPRREPPPGEVVRATVSN-----TEYLEPSHNIKDII--KQYQTNPVK--------------- 3229
Fly 1926 LFASVSGGNSGPGGVVDSHATVRTQIERMEGKLSPPPAPPSGGWPGVLLPPAPSVPAPPPPIRPP 1990
Zfish 3230 ----------------------------------------------------------------- 3229
Fly 1991 SMAPPAPPPAPQSPPTARSPEPEPDYRTSSSQVVKEHVPAFIQRQERDTFGAVRQQQMISSHHLH 2055
||..|..::...::.|:|..: :..::|:.:.|..|:::
Zfish 3230 ----PAEIPRREAKVFSKKPDPHDE----AMMILKDQMSAPPQQRK------------------- 3267
Fly 2056 LEDHSASSSPAVAAWEQAERERSRSRSRSRDREDYSESVWDRAEVEGPASGSGSEKEREKRERER 2120
Zfish 3268 ----------------------------------------------------------------- 3267
Fly 2121 ERLYEIRQVERERESHKVYQPAPPRVIQASMDTTGGHRREDRTGGLATFRTHMAQKYEHERKRKS 2185
|.|.|.|| ::.| ::.
Zfish 3268 ----------------KTYTPVPP--------SSSG--------------------------KEF 3282
Fly 2186 SASSGMREELDSMHMTTPPPV-IVPAPVPPPSSTSPGLGVV-SGVLMGSGSGGSTACLTYNRVPW 2248
|...|..:.:.|:.....||| .|....|.|:..|..|.|. ..:........|....||..|||
Zfish 3283 SYDGGPMKPVKSITTKRSPPVPAVSQRFPAPAPVSRDLPVEDENIQTQLHKRSSEEHYTYTNVPW 3347
Fly 2249 KLRVRKEVFQPHEPIGPPVALDLLFAQVLGDVFGVTPCLRITPQEKSSALNMLHGHGVSVD-TLS 2312
|:.:|||||.|.:....|:.|||||.|::.|.|. ..|:|||.:|:....::...|.:... |:.
Zfish 3348 KIYLRKEVFYPKDSFNHPLILDLLFKQIVHDTFS-EACIRITTEERQKMKSIFAEHSIDASATIQ 3411
Fly 2313 NRNGSGAGGGGNGGQVRALVKRHLVDMARD-WPLYFARLFAVQGAPLYPDVSIMGVSHSG---LY 2373
:.| ||:.:|..|:| |.:||:|||...|: :...|.::.|||.| |.
Zfish 3412 DEN----------------VKKKVVVAAKDTWDIYFSRLFPASGS-VGTGVQVLSVSHRGIKLLK 3459
Fly 2374 LARRDA---DYLIVVQAISFGEIQSAVTLPRPAALQLNLRNGKHLALHAARAAAIQSMVTTFVQE 2435
:.|..| ||..|::..|:.:|. .||:|....|:.||.|.| |.|.:|:|..:::|:..|:.|
Zfish 3460 MVRSSAVAPDYFRVLRPYSYTDIM-FVTIPSKNMLEFNLNNEK-LILFSAKAPQVKTMIDYFITE 3522
Fly 2436 FRKSQSKASTLSSGARAAAQTLN------VPLERLESRQAHAQRNEHGVDGGSRQN--------- 2485
.:|.......:.:........|: :.|:::| |:|.|....
Zfish 3523 LKKDSDYVVAVRNYITDDRTLLSFHKGDIIRLQKME-----------GLDAGQYYGCIVKKKVIL 3576
Fly 2486 -EQLQQSELHHHLQQQQQQQQQQQHHQQQQQQQQLEDAMEEQHMATDHQQQQQQQLGQQQGQQQR 2549
|:|::.......:......:......:..|.....|.: ::..|.:::.:.:.|:.
Zfish 3577 LEELKRDTPDFGWKFGAIHGRSGVFPVEFVQPVAAPDFI---NIPVDKKEEPKNKQGRV------ 3632
Fly 2550 FLKQQSYLHSARKSNAGQQPSSLTNGQVHHQEQMLQQQQQQSQSLPHH------DLDANYLQDES 2608
.::|....:..:....|..::.::.....|:....: |:|...|||
Zfish 3633 ------------AASAAVAVAVGSAAAAHELDRTIEVASPVSEYTEAYTDSTDMDIDERILQD-- 3683
Fly 2609 NGGTPPSVTKYSLLQFAMQHFRNDQLRDADRHHER--HQSAANRSYAELVKWQGHAIRLPLLRLP 2671
.:|::::||.::||..|.::....::: .:|...|..:|:||:....|:..|:...
Zfish 3684 --------VQYNMVEFAKKYFRGAQRKNGGDSYKKKSKKSKEPRDPSEMVKFSKSPIQESLIEFT 3740
Fly 2672 ND-LAPLALECFDCILRYCGDIPLDPDLTEVKCVYTVLMHCHKYLALRDEVYCQLMKQTTANRSP 2735
:: |..:|.|.|..|:::.||.|:... .|...:.|:|....:|..:|||.|||:::|.|.|.|.
Zfish 3741 DENLNKVAAEIFLAIMKFMGDYPMKGQ-AEQDVISTILRLSGEYGLMRDEAYCQVLRQITGNTSS 3804
Fly 2736 CPDSSQRAWRLLSILAAYFGCSDALRPYLMEHLTSAASDRRRSCHGTAAVCLTNLRKTARCGGRK 2800
..:|.||.||||.|..||:.||:.|:|||:::|....:.......|.|..|..|||||.:.|||.
Zfish 3805 KTESCQRGWRLLYIFTAYYKCSEVLKPYLLKYLQDVCASPGVHFQGIAKACEQNLRKTFQYGGRI 3869
Fly 2801 NVPSVEEVTAVSAGRSARRQIYRLPGGAERVVNTRCSTVVADVIAELCALLGVESEAEQQEFSLY 2865
..|:..|:.|:.||||::||::.||||.||.:..:..:|..|.|.|||..:|:.......|::::
Zfish 3870 EHPNGMELKAMLAGRSSKRQLFLLPGGIERHLKIKTCSVALDAIEELCYEMGLHKLEALDEYAVF 3934
Fly 2866 CIVQGDAFTMPLAADEYILDVTTELLKSGQPFYLIFCRSVWHFALKREPAPMPLYVEVLFNQVAP 2930
.:........||...|||||:|||.......:.|.|.|.:|...||.: ..|.|.:.:|||.|
Zfish 3935 VVTNRGQNVRPLNKREYILDITTEAEHVDSNYSLWFRRVIWTQPLKFD---NELGVTMHYNQVYP 3996
Fly 2931 DYLEGLLLELPGNGVPVPEMVRDMARIAALLHRAADLSHVPAMKEIKFLLPKPALGIREIRPAQW 2995
|||:|||..|| .|....:.::.:|::|||.|||.|..::|.:.|::..:|....|:: |..||
Zfish 3997 DYLKGLLTVLP-QGKASEQQLQQVAKLAALQHRAKDSLYLPTIHEVQEYIPTQLSGLQ--RAQQW 4058
Fly 2996 VGLVQSAWPQVANLSPGQVKAQFLNVLATWPLFGSSFFAVKRIWAEEGPHVEDNHSPMWRDLILA 3060
:.:......||..|||.|.|||||.:::.:|:||||||.: :..::|.:....:||
Zfish 4059 LNMATQHMQQVQPLSPHQAKAQFLGLVSAFPMFGSSFFYI----------LSSSNSAVDTPCVLA 4113
Fly 3061 LNRRGVLFLDPNTHETLQHWSFMEVISTRKVRSEDGAL--FLDMKVGNLMQQRVIRVQTEQAHEI 3123
:|:.|:.||...|||.:..:...||.|||..|...|:. ::::.:|:||.||:.::|.||:.|:
Zfish 4114 VNQNGLNFLSKETHEPMVKFPLKEVQSTRTQRPTAGSSYPYVEIMLGDLMSQRITQLQLEQSLEL 4178
Fly 3124 SRLVRQYITMAQISQRDKR 3142
.|:|..::... :|.|:||
Zfish 4179 CRVVAMHMENL-LSVREKR 4196
| 
