Sequence 1: | NP_001036269.2 | Gene: | Myo10A / 32028 | FlyBaseID: | FBgn0263705 | Length: | 3145 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_061198.2 | Gene: | MYO5C / 55930 | HGNCID: | 7604 | Length: | 1742 | Species: | Homo sapiens |
Alignment Length: | 1041 | Identity: | 336/1041 - (32%) |
---|---|---|---|
Similarity: | 525/1041 - (50%) | Gaps: | 149/1041 - (14%) |
- Green bases have known domain annotations that are detailed below.
Fly 156 GVEDMTLLDDLHEASLLWNLRLRY-DKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLG 219
Fly 220 SLPPHLFAIGAAAHAALP---SPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQI 281
Fly 282 LEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQYLLEKSRIVTQAPGERNYHV 345
Fly 346 FYELLGGLSETERSKYGLLEADKYFYLNQGATDCASG---RVDWESLQGAMQVLGVSEGEREGIV 407
Fly 408 RVLAAVLHLGNVYFHRRQLRHGQEGVEVG-SDAEIKWAAHLLHISADGLHRALTSRTTEARAERL 471
Fly 472 HTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENSFEQ 536
Fly 537 LCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNF 601
Fly 602 PRATDLSFLEKCHYNHALSE--LYARPRIGAQEFGVTHYAGQVWYCVDGFLDKNRDALRGDVLEL 664
Fly 665 LASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKP------------RTPTVAARFADSLQ 717
Fly 718 QLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVER 782
Fly 783 YRHLLPSPLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLREALHRALESGRTERLRRAA 847
Fly 848 VSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQR--------------------------- 885
Fly 886 -YERLRKGALTAQRLWRGRQARRRVQQLRSDHRR---RQEAREAAQRAREAREAKQAVLERSQLS 946
Fly 947 YLDIPAELAFIYSKLQGWSPP-HGDRHLVKVLGTV----PGPPSSAVQLPEDLGQFSF------- 999
Fly 1000 ----------GKFSSVYCNGLRLQPRREPITAPL-------------LTRAASRD---------- 1031
Fly 1032 ---------QDFQDALAVFKLILRWSNDKALEGAKEKLLADYIVH-KALSSRGLRDEILVQLCNQ 1086
Fly 1087 V 1087 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Myo10A | NP_001036269.2 | MYSc | 156..836 | CDD:214580 | 263/702 (37%) |
MYSc_Myo15 | 169..828 | CDD:276838 | 255/681 (37%) | ||
MyTH4 | 1014..1171 | CDD:295320 | 22/107 (21%) | ||
MyTH4 | 2704..2810 | CDD:279165 | |||
B41 | 2823..3033 | CDD:214604 | |||
FERM_B-lobe | 2920..3025 | CDD:271216 | |||
FERM_C_MyoXV | 3029..3138 | CDD:270022 | |||
MYO5C | NP_061198.2 | Myosin_N | 12..48 | CDD:280832 | |
MYSc | 62..752 | CDD:214580 | 265/705 (38%) | ||
MYSc_Myo5 | 81..741 | CDD:276831 | 255/681 (37%) | ||
Actin-binding. /evidence=ECO:0000255|PROSITE-ProRule:PRU00782 | 632..654 | 9/21 (43%) | |||
IQ | 810..828 | CDD:197470 | 0/17 (0%) | ||
COG1340 | 890..1150 | CDD:224259 | 34/190 (18%) | ||
P-loop_NTPase | <910..>1163 | CDD:304359 | 28/167 (17%) | ||
GBP_C | <927..1030 | CDD:303769 | 12/102 (12%) | ||
coiled coil | 997..1010 | CDD:293879 | 1/12 (8%) | ||
coiled coil | 1019..1030 | CDD:293879 | 2/10 (20%) | ||
Rab5-bind | 1020..1345 | CDD:286404 | 16/57 (28%) | ||
DUF3585 | 1160..1326 | CDD:304905 | |||
Myo5c_CBD | 1369..1736 | CDD:271260 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000014 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100101 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |