Protein Alignment Myo10A and myo1ea

DIOPT Version :10

• Sequence 1: NP_001036269.2
• Gene: Myo10A / 32028
• FlyBaseID: FBgn0263705
• Length: 3145
• Species: Drosophila melanogaster
• Sequence 2: XP_005168983.2
• Gene: myo1ea / 555285
• ZFINID: ZDB-GENE-030131-5127
• Length: 1117
• Species: Danio rerio
• Alignment Length: 832
• Identity: 273/832 - (32%)
• Similarity: 421/832 - (50%)
• Gaps: 119/832 - (14%)

  Fly   155 SGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLG 219
            |||:||.||..::|.:::.||:.||....|:|:.|.:||:|||:|..| .:|.:..:.|.|....
Zfish    19 SGVDDMVLLSKINEDAIVENLKKRYMDDYIFTYIGPVLISVNPFKQMP-YFGEKEIEMYQGAAQY 82

  Fly   220 SLPPHLFAIGAAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAVVPGGGSASAVITEQI 281
            ..|||::|:....:..:   ...|.|:||||||:|||.:.|.:|.|::. |.|||.....:.:.|
Zfish    83 ENPPHIYALADNMYRNMMIDRENQCVIISGESGAGKTVAAKYIMGYISK-VSGGGPRVQHVKDII 146

  Fly   282 LEAAPLLEAFGNARTARNDNSSRFGKYLEVYFKSGAIV-GAKITQYLLEKSRIVTQAPGERNYHV 345
            |::.|||||||||:|.||:||||||||.|:.|.||... |.||:.:||||||:|.:.||||::|:
Zfish   147 LQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSSGGEPDGGKISNFLLEKSRVVMRNPGERSFHI 211

  Fly   346 FYELLGGLSETERSKYGLLEADKYFYLNQGAT---DCASGRVDWESLQGAMQVLGVSEGEREGIV 407
            ||:|:.|.|..::|..|:...|.|.||||..:   |..:.:.|::....||.|:|:|..:|..::
Zfish   212 FYQLIEGASGDQKSSLGITSLDYYTYLNQSGSYKVDDINDKHDFQETLHAMDVIGISGIDRTMVL 276

  Fly   408 RVLAAVLHLGNVYFHRRQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSRTTE----ARA 468
            :::|.:|||||:.|     |.......|.:|..:.:.|.||.|..:.|...||||..:    .::
Zfish   277 QIVAGILHLGNINF-----REAGNYAAVENDEFLAFPAFLLGIDQERLKEKLTSRKMDGKWGGKS 336

  Fly   469 ERLHTPLGIDQALDARDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENS 533
            |.:...|.::||...|||.:|||::.:|::||..||..:.|  .|....|.:|||:|||...:|.
Zfish   337 ESIDVTLNVEQACFTRDALSKALHSRVFDYLVESINKAMVK--EHQELNIGVLDIYGFEIFQKNG 399

  Fly   534 FEQLCINYANENLQLYFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKK--PVGICHLLD 596
            |||.|||:.||.||..|.:...|.||.||.:|.:.||.:.:.:|..|..|:..|  |.||..:||
Zfish   400 FEQFCINFVNEKLQQIFIELTLKAEQDEYVQEGIRWTQIEYFNNKIVCDLIESKINPPGIMSILD 464

  Fly   597 DESNFPRA----TDLSFLEKC--------HYNHALSELYARPRIGAQEFGVTHYAGQVWYCVDGF 649
            |......|    .|.:.|:|.        |:|.           ..|.|.:.||||:|.|..:||
Zfish   465 DVCATMHAKGEGADQTMLQKLRMQINNHEHFNS-----------WNQGFIIHHYAGKVSYDAEGF 518

  Fly   650 LDKNRDALRGDVLELLASSRLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFAD 714
            .::|||.|..|::||:.||.:..:..|             .|:..|..   .|.|..|..::...
Zfish   519 CERNRDVLFTDLIELMQSSEIAFIRAL-------------FPENLNAE---KKGRPTTAGSKIKK 567

  Fly   715 SLQQLLQSMGRCHPWFVRCIKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHF 779
            ....|:.::.:|.|.::||||||:.|.....:...|..|:.|||:.:.|::|:.||..|..|:.|
Zfish   568 QANDLVSTLMKCTPHYIRCIKPNETKKPKDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFRKF 632

  Fly   780 VERYRHLLPS--PLARGTPYRELCRALLEAMPRTGVEGPDYQLGATRVFLR--EALHRALESGRT 840
            :.||..|...  |..||    :..:.:|..:....::...||||.|::|::  |:|. .||..|.
Zfish   633 LNRYAILTKESWPTWRG----DEKQGVLHLLRSVNMDQDQYQLGHTKIFIKAPESLF-LLEETRE 692

  Fly   841 ERLRRAAVSVQRHVRGMLVRRQLARRQAAATRLQARWRGQRAQQRYERLRKGALTAQRLWRGRQA 905
            .:.                       ...|..:|..||...|:::|.::|:   .|..|...::.
Zfish   693 RKF-----------------------DGYARTIQTAWRKYCARKKYVQMRE---EASDLLLNKKE 731

  Fly   906 RRRVQQLRS--------DHRRRQEAREAAQRAREAREAKQAVLERSQLSYLD 949
            |||....|:        |.|               .|.:|.|.:|.::.:.|
Zfish   732 RRRHSLNRNFVGDYLGMDDR---------------PELRQFVGKREKIDFAD 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo10A	NP_001036269.2	MYSc_Myo15	169..828	CDD:276838	240/685 (35%)
		PTZ00121	<828..>943	CDD:173412	23/124 (19%)
		MyTH4	1014..1171	CDD:470587
		Ubl1_cv_Nsp3_N-like	1178..>1245	CDD:475130
		MyTH4	2704..2810	CDD:459939
		FERM_B-lobe	2920..3025	CDD:271216
		FERM_C_MyoXV	3029..3138	CDD:270022
myo1ea	XP_005168983.2	None