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Protein Alignment Myo10A and myo6

DIOPT Version :10

Sequence 1:	NP_001036269.2	Gene:	Myo10A / 32028	FlyBaseID:	FBgn0263705	Length:	3145	Species:	Drosophila melanogaster
Sequence 2:	XP_031758531.1	Gene:	myo6 / 493193	XenbaseID:	XB-GENE-1012303	Length:	1300	Species:	Xenopus tropicalis

Alignment Length:	980	Identity:	311/980 - (31%)
Similarity:	457/980 - (46%)	Gaps:	185/980 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 QTFALQPGEGSLRARQDLGSSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYK 199
            :|| |.|......|.:|. |..|||...|..|:||:||.|:::||.|..|||:..:||||||||.
Frog    39 KTF-LAPINQVFPAEEDT-SKHVEDNCSLMYLNEATLLHNIQVRYSKDKIYTYVANILIAVNPYF 101

  Fly   200 MFPDAYGLEVAKQYAGRPLGSLPPHLFAIGAAAH---AALPSPQVVVISGESGSGKTESTKLVMQ 261
            ..|..|..|..|||.|:.||:||||::||...|.   ..|...|.:::|||||:||||:||.|::
Frog   102 DVPKLYTSEQIKQYHGKSLGTLPPHVYAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLR 166

  Fly   262 YLAAVVPGGGSASAVITEQILEAAPLLEAFGNARTARNDNSSRFGKYLEVYF-KSGAIVGAKITQ 325
            ||......|..    |.|:|:||.|||||||||:|.||:|||||||::|::| :..::||..::.
Frog   167 YLTESYGSGQD----IDERIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKNSVVGGFVSH 227

  Fly   326 YLLEKSRIVTQAPGERNYHVFYELLGGLSETERSKYGLLEADKYFYLNQGATD-CASGRVDWESL 389
            ||||||||..|...|||||:||.|..|..|..|.|..|...|.:.|||:|.|. .||...|.:.|
Frog   228 YLLEKSRICVQGQDERNYHIFYRLCAGAPEDIRQKLFLCSPDTFRYLNRGCTRYFASKDTDKQIL 292

  Fly   390 QG-------------------------------AMQVLGVSEGEREGIVRVLAAVLHLGNVYFHR 423
            |.                               ||:.:|:.:.|:..:.||:|.||||||:.|..
Frog   293 QNRKSPEEDEYLKHGALKDPLLDDHGDFNRMCIAMKKIGLDDTEKLDLFRVVAGVLHLGNIDFEE 357

  Fly   424 RQLRHGQEGVEVGSDAEIKWAAHLLHISADGLHRALTSR---TTE--ARAERLHTPLGIDQALDA 483
            .....|...:...|...::..|.||.:..|.|..:||||   ||.  .:...:..||.:.||.:|
Frog   358 AGSTSGGCTLRKKSSESLQCCAKLLGLDQDDLQVSLTSRVMLTTAGGTKGTVIKVPLKVQQAENA 422

  Fly   484 RDAFAKALYAGLFNWLVSRINSIVQKGGTHDAHRISILDIFGFEDLAENSFEQLCINYANENLQL 548
            |||.|||:|:.||:.:|:|:|....  ....:..|.:|||.|||....|||||.||||.||.||.
Frog   423 RDALAKAIYSHLFDHVVNRVNQCFP--FERSSFFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQ 485

  Fly   549 YFNKHVFKLEQAEYARERLEWTPLAWDDNLPVIHLLAKKPVGICHLLDDESNFPRATDLSFLEKC 613
            :||:.:.|.||..|.:|.|....:.:.||...|.|:..|.|||..:||:|:..|:.||..|....
Frog   486 FFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPTDQHFTSAV 550

  Fly   614 HYNH---------ALSELYARPRIGAQE-FGVTHYAGQVWYCVDGFLDKNRDALRGDVLELLASS 668
            |..|         ..|:|.....|...| |.|.|:||.|.|....|::||.|||...:..|:..|
Frog   551 HQKHKNHFRLTIPRKSKLAVHRNIRDDEGFIVRHFAGAVCYETTQFVEKNNDALHMSLESLICES 615

  Fly   669 RLPLVGELTKQLRAQRDAGKTLPKGSNGRFVTMKPRTPTVAARFADSLQQLLQSMGRCHPWFVRC 733
            :...|.||.:.....:|..:...|.|   |:       :|..:|...|..||:.:......|:||
Frog   616 KDKFVRELFESANNHKDLKQKTGKLS---FI-------SVGNKFKTQLNLLLEKLRSTGSSFIRC 670

  Fly   734 IKPNQEKHALRMDMPCVLQQLRYLGMLDTIQIRQRGYPVRLRFQHFVERYRHLLPSPLARGTPYR 798
            ||||.:..:.:.:...:|.||:..||:..:.:.|.|:|.|..|......|:..:|:.::|..| |
Frog   671 IKPNLKMTSHQFEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPAKMSRLDP-R 734

  Fly   799 ELCRALLEAMPRTGVEGPDYQLGATRVFLR-------EALHRALESGRTERLRR----------- 845
            ..|:||.:|:   |:...||:.|.|:||.|       :.:.::......|.:||
Frog   735 LFCKALFKAL---GLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELIRRVNHWLICSRWK 796

  Fly   846 ---------------------AAVSVQRHVR-------------GM------------------- 857
                                 |.:.:|:.:|             ||
Frog   797 KVQWCALCVIKLKNKIQYRASACIKMQKTIRMWLCRKKHKPRIDGMVKVQTLKKRLDKFNEVVNA 861

  Fly   858 ------------------------------LVRRQLARR-----QAAATRLQARWRGQRAQQRYE 887
                                          :.|.|:.|.     :::...|.:..:.::.::..|
Frog   862 LKEGKAEMSKQVKDLELSIDALLSKIKNTIMTREQIEREYDNLVKSSGQLLNSLQKRKKEEEEAE 926

  Fly   888 RLRKGALTAQRLWRGRQARRRVQQLR--SDHRRRQEAREAAQRAREAREAKQAVLERSQLSYLDI 950
            ||.|   ..:.:.|.|:.|...::||  .::.||.:|...|:|.:|..|.|:...|..::. .::
Frog   927 RLHK---IQEEMERERKRREAEEELRRKEENERRLKAEIEAKRKQEEEERKKREEEEKRIQ-AEV 987

  Fly   951 PAELA 955
            ..:||
Frog   988 EMQLA 992

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.